Hepatectomy Plus Chemotherapy or Chemotherapy Alone for Resectable Liver and Unresectable Lung Metastases from Colorectal Adenocarcinoma (LUNA): A Randomized Phase II Trial.
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| Title: | Hepatectomy Plus Chemotherapy or Chemotherapy Alone for Resectable Liver and Unresectable Lung Metastases from Colorectal Adenocarcinoma (LUNA): A Randomized Phase II Trial. |
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| Authors: | Folkert IW; Department of Surgical Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX, USA., Mehran R; Department of Thoracic Surgery, The University of Texas MD Anderson Cancer Center, Houston, TX, USA., Sun R; Department of Biostatistics, The University of Texas MD Anderson Cancer Center, Houston, TX, USA., Morris VK; Department of Gastrointestinal Medical Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX, USA., Overman MJ; Department of Gastrointestinal Medical Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX, USA., Kee B; Department of Gastrointestinal Medical Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX, USA., Antonoff MB; Department of Thoracic Surgery, The University of Texas MD Anderson Cancer Center, Houston, TX, USA., Tzeng CW; Department of Surgical Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX, USA., Dasari A; Department of Gastrointestinal Medical Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX, USA., Tran Cao H; Department of Surgical Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX, USA., Parseghian CM; Department of Gastrointestinal Medical Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX, USA., Vilar E; Department of Gastrointestinal Medical Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX, USA., Willis J; Department of Gastrointestinal Medical Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX, USA., Newhook TE; Department of Surgical Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX, USA., Hofstetter W; Department of Thoracic Surgery, The University of Texas MD Anderson Cancer Center, Houston, TX, USA., Kopetz SE; Department of Gastrointestinal Medical Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX, USA., Vauthey JN; Department of Surgical Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX, USA., Chun YS; Department of Surgical Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX, USA. yschun@mdanderson.org. |
| Source: | Annals of surgical oncology [Ann Surg Oncol] 2026 Apr; Vol. 33 (4), pp. 2899-2907. Date of Electronic Publication: 2025 Dec 10. |
| Publication Type: | Journal Article; Clinical Trial, Phase II; Randomized Controlled Trial |
| Journal Info: | Publisher: Springer Country of Publication: United States NLM ID: 9420840 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1534-4681 (Electronic) Linking ISSN: 10689265 NLM ISO Abbreviation: Ann Surg Oncol Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
| FullText | Text: Availability: 0 |
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| Header | DbId: mdl DbLabel: MEDLINE Ultimate An: 41369813 AccessLevel: 2 PubType: Academic Journal PubTypeId: academicJournal PreciseRelevancyScore: 0 |
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| Items | – Name: Title Label: Title Group: Ti Data: Hepatectomy Plus Chemotherapy or Chemotherapy Alone for Resectable Liver and Unresectable Lung Metastases from Colorectal Adenocarcinoma (LUNA): A Randomized Phase II Trial. – Name: Author Label: Authors Group: Au Data: <searchLink fieldCode="AU" term="%22Folkert+IW%22">Folkert IW</searchLink>; Department of Surgical Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX, USA.<br /><searchLink fieldCode="AU" term="%22Mehran+R%22">Mehran R</searchLink>; Department of Thoracic Surgery, The University of Texas MD Anderson Cancer Center, Houston, TX, USA.<br /><searchLink fieldCode="AU" term="%22Sun+R%22">Sun R</searchLink>; Department of Biostatistics, The University of Texas MD Anderson Cancer Center, Houston, TX, USA.<br /><searchLink fieldCode="AU" term="%22Morris+VK%22">Morris VK</searchLink>; Department of Gastrointestinal Medical Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX, USA.<br /><searchLink fieldCode="AU" term="%22Overman+MJ%22">Overman MJ</searchLink>; Department of Gastrointestinal Medical Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX, USA.<br /><searchLink fieldCode="AU" term="%22Kee+B%22">Kee B</searchLink>; Department of Gastrointestinal Medical Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX, USA.<br /><searchLink fieldCode="AU" term="%22Antonoff+MB%22">Antonoff MB</searchLink>; Department of Thoracic Surgery, The University of Texas MD Anderson Cancer Center, Houston, TX, USA.<br /><searchLink fieldCode="AU" term="%22Tzeng+CW%22">Tzeng CW</searchLink>; Department of Surgical Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX, USA.<br /><searchLink fieldCode="AU" term="%22Dasari+A%22">Dasari A</searchLink>; Department of Gastrointestinal Medical Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX, USA.<br /><searchLink fieldCode="AU" term="%22Tran+Cao+H%22">Tran Cao H</searchLink>; Department of Surgical Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX, USA.<br /><searchLink fieldCode="AU" term="%22Parseghian+CM%22">Parseghian CM</searchLink>; Department of Gastrointestinal Medical Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX, USA.<br /><searchLink fieldCode="AU" term="%22Vilar+E%22">Vilar E</searchLink>; Department of Gastrointestinal Medical Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX, USA.<br /><searchLink fieldCode="AU" term="%22Willis+J%22">Willis J</searchLink>; Department of Gastrointestinal Medical Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX, USA.<br /><searchLink fieldCode="AU" term="%22Newhook+TE%22">Newhook TE</searchLink>; Department of Surgical Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX, USA.<br /><searchLink fieldCode="AU" term="%22Hofstetter+W%22">Hofstetter W</searchLink>; Department of Thoracic Surgery, The University of Texas MD Anderson Cancer Center, Houston, TX, USA.<br /><searchLink fieldCode="AU" term="%22Kopetz+SE%22">Kopetz SE</searchLink>; Department of Gastrointestinal Medical Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX, USA.<br /><searchLink fieldCode="AU" term="%22Vauthey+JN%22">Vauthey JN</searchLink>; Department of Surgical Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX, USA.<br /><searchLink fieldCode="AU" term="%22Chun+YS%22">Chun YS</searchLink>; Department of Surgical Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX, USA. yschun@mdanderson.org. – Name: TitleSource Label: Source Group: Src Data: <searchLink fieldCode="JN" term="%229420840%22">Annals of surgical oncology</searchLink> [Ann Surg Oncol] 2026 Apr; Vol. 33 (4), pp. 2899-2907. <i>Date of Electronic Publication: </i>2025 Dec 10. – Name: TypePub Label: Publication Type Group: TypPub Data: Journal Article; Clinical Trial, Phase II; Randomized Controlled Trial – Name: TitleSource Label: Journal Info Group: Src Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Springer%22">Springer </searchLink><i>Country of Publication: </i>United States <i>NLM ID: </i>9420840 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1534-4681 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2210689265%22">10689265 </searchLink><i>NLM ISO Abbreviation: </i>Ann Surg Oncol <i>Subsets: </i>MEDLINE |
| PLink | https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=mdl&AN=41369813 |
| RecordInfo | BibRecord: BibEntity: Identifiers: – Type: doi Value: 10.1245/s10434-025-18854-w Languages: – Code: eng Text: English PhysicalDescription: Pagination: StartPage: 2899 Titles: – TitleFull: Hepatectomy Plus Chemotherapy or Chemotherapy Alone for Resectable Liver and Unresectable Lung Metastases from Colorectal Adenocarcinoma (LUNA): A Randomized Phase II Trial. Type: main BibRelationships: HasContributorRelationships: – PersonEntity: Name: NameFull: Folkert IW – PersonEntity: Name: NameFull: Mehran R – PersonEntity: Name: NameFull: Sun R – PersonEntity: Name: NameFull: Morris VK – PersonEntity: Name: NameFull: Overman MJ – PersonEntity: Name: NameFull: Kee B – PersonEntity: Name: NameFull: Antonoff MB – PersonEntity: Name: NameFull: Tzeng CW – PersonEntity: Name: NameFull: Dasari A – PersonEntity: Name: NameFull: Tran Cao H – PersonEntity: Name: NameFull: Parseghian CM – PersonEntity: Name: NameFull: Vilar E – PersonEntity: Name: NameFull: Willis J – PersonEntity: Name: NameFull: Newhook TE – PersonEntity: Name: NameFull: Hofstetter W – PersonEntity: Name: NameFull: Kopetz SE – PersonEntity: Name: NameFull: Vauthey JN – PersonEntity: Name: NameFull: Chun YS IsPartOfRelationships: – BibEntity: Dates: – D: 01 M: 04 Text: 2026 Apr Type: published Y: 2026 Identifiers: – Type: issn-electronic Value: 1534-4681 Numbering: – Type: volume Value: 33 – Type: issue Value: 4 Titles: – TitleFull: Annals of surgical oncology Type: main |
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