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Inhibition of adipocyte lipolysis by vaspin impairs thermoregulation in vivo.

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Title: Inhibition of adipocyte lipolysis by vaspin impairs thermoregulation in vivo.
Authors: Rapöhn I; Helmholtz Institute for Metabolic, Obesity and Vascular Research (HI-MAG) of the Helmholtz Zentrum München at the University of Leipzig and University Hospital Leipzig, Leipzig, Germany., Broghammer H; Helmholtz Institute for Metabolic, Obesity and Vascular Research (HI-MAG) of the Helmholtz Zentrum München at the University of Leipzig and University Hospital Leipzig, Leipzig, Germany., Hoffmann A; Helmholtz Institute for Metabolic, Obesity and Vascular Research (HI-MAG) of the Helmholtz Zentrum München at the University of Leipzig and University Hospital Leipzig, Leipzig, Germany., Möhlis K; Helmholtz Institute for Metabolic, Obesity and Vascular Research (HI-MAG) of the Helmholtz Zentrum München at the University of Leipzig and University Hospital Leipzig, Leipzig, Germany., Moormann A; Helmholtz Institute for Metabolic, Obesity and Vascular Research (HI-MAG) of the Helmholtz Zentrum München at the University of Leipzig and University Hospital Leipzig, Leipzig, Germany., Kaczmarek I; Rudolf Schönheimer Institute of Biochemistry, Medical Faculty, University of Leipzig, Leipzig, Germany., Thor D; Rudolf Schönheimer Institute of Biochemistry, Medical Faculty, University of Leipzig, Leipzig, Germany., Großkopf H; Department Molecular Toxicology, Helmholtz Centre for Environmental Research (UFZ), Leipzig, Germany., Krieg L; Department Molecular Toxicology, Helmholtz Centre for Environmental Research (UFZ), Leipzig, Germany., Karkossa I; Department Molecular Toxicology, Helmholtz Centre for Environmental Research (UFZ), Leipzig, Germany., Schubert K; Department Molecular Toxicology, Helmholtz Centre for Environmental Research (UFZ), Leipzig, Germany.; Cell Biology, Faculty of Environment and Natural Science, Brandenburg University of Technology Cottbus-Senftenberg, Senftenberg, Germany., von Bergen M; Department Molecular Toxicology, Helmholtz Centre for Environmental Research (UFZ), Leipzig, Germany.; Institute of Biochemistry, Faculty of Life Sciences, University of Leipzig, Leipzig, Germany., Krause K; Leipzig University Medical Center, Divisions of Endocrinology and Nephrology, University of Leipzig, Leipzig, Germany.; German Center for Diabetes Research, Neuherberg, Germany., Breitfeld J; Leipzig University Medical Center, Divisions of Endocrinology and Nephrology, University of Leipzig, Leipzig, Germany., Kovacs P; Leipzig University Medical Center, Divisions of Endocrinology and Nephrology, University of Leipzig, Leipzig, Germany., Klöting N; Helmholtz Institute for Metabolic, Obesity and Vascular Research (HI-MAG) of the Helmholtz Zentrum München at the University of Leipzig and University Hospital Leipzig, Leipzig, Germany., Nuwayhid R; Department of Orthopaedic, Trauma and Plastic Surgery, Division of Plastic, Aesthetic and Special Hand Surgery, University Hospital Leipzig, Leipzig, Germany., Langer S; Department of Orthopaedic, Trauma and Plastic Surgery, Division of Plastic, Aesthetic and Special Hand Surgery, University Hospital Leipzig, Leipzig, Germany., Ghosh A; Laboratory of Translational Nutrition Biology, Institute of Food, Nutrition and Health, ETH Zürich, Schwerzenbach, Switzerland., Wolfrum C; Laboratory of Translational Nutrition Biology, Institute of Food, Nutrition and Health, ETH Zürich, Schwerzenbach, Switzerland., Stumvoll M; Helmholtz Institute for Metabolic, Obesity and Vascular Research (HI-MAG) of the Helmholtz Zentrum München at the University of Leipzig and University Hospital Leipzig, Leipzig, Germany.; Leipzig University Medical Center, Divisions of Endocrinology and Nephrology, University of Leipzig, Leipzig, Germany., Blüher M; Helmholtz Institute for Metabolic, Obesity and Vascular Research (HI-MAG) of the Helmholtz Zentrum München at the University of Leipzig and University Hospital Leipzig, Leipzig, Germany.; Leipzig University Medical Center, Divisions of Endocrinology and Nephrology, University of Leipzig, Leipzig, Germany.; German Center for Diabetes Research, Neuherberg, Germany., Heiker JT; Helmholtz Institute for Metabolic, Obesity and Vascular Research (HI-MAG) of the Helmholtz Zentrum München at the University of Leipzig and University Hospital Leipzig, Leipzig, Germany. john.heiker@helmholtz-munich.de.; Institute of Biochemistry, Faculty of Life Sciences, University of Leipzig, Leipzig, Germany. john.heiker@helmholtz-munich.de., Weiner J; Leipzig University Medical Center, Divisions of Endocrinology and Nephrology, University of Leipzig, Leipzig, Germany.
Source: Nature communications [Nat Commun] 2025 Dec 10; Vol. 16 (1), pp. 11075. Date of Electronic Publication: 2025 Dec 10.
Publication Type: Journal Article
Journal Info: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE
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  Data: Inhibition of adipocyte lipolysis by vaspin impairs thermoregulation in vivo.
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  Data: <searchLink fieldCode="AU" term="%22Rapöhn+I%22">Rapöhn I</searchLink>; Helmholtz Institute for Metabolic, Obesity and Vascular Research (HI-MAG) of the Helmholtz Zentrum München at the University of Leipzig and University Hospital Leipzig, Leipzig, Germany.<br /><searchLink fieldCode="AU" term="%22Broghammer+H%22">Broghammer H</searchLink>; Helmholtz Institute for Metabolic, Obesity and Vascular Research (HI-MAG) of the Helmholtz Zentrum München at the University of Leipzig and University Hospital Leipzig, Leipzig, Germany.<br /><searchLink fieldCode="AU" term="%22Hoffmann+A%22">Hoffmann A</searchLink>; Helmholtz Institute for Metabolic, Obesity and Vascular Research (HI-MAG) of the Helmholtz Zentrum München at the University of Leipzig and University Hospital Leipzig, Leipzig, Germany.<br /><searchLink fieldCode="AU" term="%22Möhlis+K%22">Möhlis K</searchLink>; Helmholtz Institute for Metabolic, Obesity and Vascular Research (HI-MAG) of the Helmholtz Zentrum München at the University of Leipzig and University Hospital Leipzig, Leipzig, Germany.<br /><searchLink fieldCode="AU" term="%22Moormann+A%22">Moormann A</searchLink>; Helmholtz Institute for Metabolic, Obesity and Vascular Research (HI-MAG) of the Helmholtz Zentrum München at the University of Leipzig and University Hospital Leipzig, Leipzig, Germany.<br /><searchLink fieldCode="AU" term="%22Kaczmarek+I%22">Kaczmarek I</searchLink>; Rudolf Schönheimer Institute of Biochemistry, Medical Faculty, University of Leipzig, Leipzig, Germany.<br /><searchLink fieldCode="AU" term="%22Thor+D%22">Thor D</searchLink>; Rudolf Schönheimer Institute of Biochemistry, Medical Faculty, University of Leipzig, Leipzig, Germany.<br /><searchLink fieldCode="AU" term="%22Großkopf+H%22">Großkopf H</searchLink>; Department Molecular Toxicology, Helmholtz Centre for Environmental Research (UFZ), Leipzig, Germany.<br /><searchLink fieldCode="AU" term="%22Krieg+L%22">Krieg L</searchLink>; Department Molecular Toxicology, Helmholtz Centre for Environmental Research (UFZ), Leipzig, Germany.<br /><searchLink fieldCode="AU" term="%22Karkossa+I%22">Karkossa I</searchLink>; Department Molecular Toxicology, Helmholtz Centre for Environmental Research (UFZ), Leipzig, Germany.<br /><searchLink fieldCode="AU" term="%22Schubert+K%22">Schubert K</searchLink>; Department Molecular Toxicology, Helmholtz Centre for Environmental Research (UFZ), Leipzig, Germany.; Cell Biology, Faculty of Environment and Natural Science, Brandenburg University of Technology Cottbus-Senftenberg, Senftenberg, Germany.<br /><searchLink fieldCode="AU" term="%22von+Bergen+M%22">von Bergen M</searchLink>; Department Molecular Toxicology, Helmholtz Centre for Environmental Research (UFZ), Leipzig, Germany.; Institute of Biochemistry, Faculty of Life Sciences, University of Leipzig, Leipzig, Germany.<br /><searchLink fieldCode="AU" term="%22Krause+K%22">Krause K</searchLink>; Leipzig University Medical Center, Divisions of Endocrinology and Nephrology, University of Leipzig, Leipzig, Germany.; German Center for Diabetes Research, Neuherberg, Germany.<br /><searchLink fieldCode="AU" term="%22Breitfeld+J%22">Breitfeld J</searchLink>; Leipzig University Medical Center, Divisions of Endocrinology and Nephrology, University of Leipzig, Leipzig, Germany.<br /><searchLink fieldCode="AU" term="%22Kovacs+P%22">Kovacs P</searchLink>; Leipzig University Medical Center, Divisions of Endocrinology and Nephrology, University of Leipzig, Leipzig, Germany.<br /><searchLink fieldCode="AU" term="%22Klöting+N%22">Klöting N</searchLink>; Helmholtz Institute for Metabolic, Obesity and Vascular Research (HI-MAG) of the Helmholtz Zentrum München at the University of Leipzig and University Hospital Leipzig, Leipzig, Germany.<br /><searchLink fieldCode="AU" term="%22Nuwayhid+R%22">Nuwayhid R</searchLink>; Department of Orthopaedic, Trauma and Plastic Surgery, Division of Plastic, Aesthetic and Special Hand Surgery, University Hospital Leipzig, Leipzig, Germany.<br /><searchLink fieldCode="AU" term="%22Langer+S%22">Langer S</searchLink>; Department of Orthopaedic, Trauma and Plastic Surgery, Division of Plastic, Aesthetic and Special Hand Surgery, University Hospital Leipzig, Leipzig, Germany.<br /><searchLink fieldCode="AU" term="%22Ghosh+A%22">Ghosh A</searchLink>; Laboratory of Translational Nutrition Biology, Institute of Food, Nutrition and Health, ETH Zürich, Schwerzenbach, Switzerland.<br /><searchLink fieldCode="AU" term="%22Wolfrum+C%22">Wolfrum C</searchLink>; Laboratory of Translational Nutrition Biology, Institute of Food, Nutrition and Health, ETH Zürich, Schwerzenbach, Switzerland.<br /><searchLink fieldCode="AU" term="%22Stumvoll+M%22">Stumvoll M</searchLink>; Helmholtz Institute for Metabolic, Obesity and Vascular Research (HI-MAG) of the Helmholtz Zentrum München at the University of Leipzig and University Hospital Leipzig, Leipzig, Germany.; Leipzig University Medical Center, Divisions of Endocrinology and Nephrology, University of Leipzig, Leipzig, Germany.<br /><searchLink fieldCode="AU" term="%22Blüher+M%22">Blüher M</searchLink>; Helmholtz Institute for Metabolic, Obesity and Vascular Research (HI-MAG) of the Helmholtz Zentrum München at the University of Leipzig and University Hospital Leipzig, Leipzig, Germany.; Leipzig University Medical Center, Divisions of Endocrinology and Nephrology, University of Leipzig, Leipzig, Germany.; German Center for Diabetes Research, Neuherberg, Germany.<br /><searchLink fieldCode="AU" term="%22Heiker+JT%22">Heiker JT</searchLink>; Helmholtz Institute for Metabolic, Obesity and Vascular Research (HI-MAG) of the Helmholtz Zentrum München at the University of Leipzig and University Hospital Leipzig, Leipzig, Germany. john.heiker@helmholtz-munich.de.; Institute of Biochemistry, Faculty of Life Sciences, University of Leipzig, Leipzig, Germany. john.heiker@helmholtz-munich.de.<br /><searchLink fieldCode="AU" term="%22Weiner+J%22">Weiner J</searchLink>; Leipzig University Medical Center, Divisions of Endocrinology and Nephrology, University of Leipzig, Leipzig, Germany.
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