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Simultaneous chromatographic quantification of upadacitinib, nilotinib, and tryptophan decoding myeloid leukemia and liver cancer integrated with ELISA and Flow cytometry.

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Title: Simultaneous chromatographic quantification of upadacitinib, nilotinib, and tryptophan decoding myeloid leukemia and liver cancer integrated with ELISA and Flow cytometry.
Authors: Saleh AM; Postgraduate Program, in Pharmaceutical Analytical Chemistry, Faculty of Pharmacy, Cairo University, Kasr El-Aini Street, Cairo 11562, Egypt; Pharmaceutical Chemistry Department, Faculty of Pharmacy, Horus University, Horus, 34518, Egypt; Biosensors Research Lab, Zewail City of Science and Technology, 6(th) October City, Giza, 12578, Egypt., Saleh OA; Medicinal and Pharmaceutical Chemistry Department, Pharmaceutical and Drug Industries Research Institute, National Research Centre, Giza, 12622, Egypt., Hassan RYA; Biosensors Research Lab, Zewail City of Science and Technology, 6(th) October City, Giza, 12578, Egypt; Applied Organic Chemistry Department, National Research Centre (NRC), Dokki, Giza, 12622, Egypt., Abd-Rabou AA; Hormones Department, Medical Research and Clinical Studies Institute, National Research Centre, Dokki, Giza, Egypt., Badawey AM; Pharmaceutical Analytical Chemistry Department, Faculty of Pharmacy, Cairo University, Kasr El-Aini Street, Cairo 11562, Egypt. Electronic address: amr.badawey@pharma.cu.edu.eg., Marzouk HM; Pharmaceutical Analytical Chemistry Department, Faculty of Pharmacy, Cairo University, Kasr El-Aini Street, Cairo 11562, Egypt. Electronic address: hodaallah.marzouk@pharma.cu.edu.eg.
Source: Journal of chromatography. B, Analytical technologies in the biomedical and life sciences [J Chromatogr B Analyt Technol Biomed Life Sci] 2026 Feb 01; Vol. 1270, pp. 124891. Date of Electronic Publication: 2025 Dec 05.
Publication Type: Journal Article
Journal Info: Publisher: Elsevier Country of Publication: Netherlands NLM ID: 101139554 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1873-376X (Electronic) Linking ISSN: 15700232 NLM ISO Abbreviation: J Chromatogr B Analyt Technol Biomed Life Sci Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: <searchLink fieldCode="AU" term="%22Saleh+AM%22">Saleh AM</searchLink>; Postgraduate Program, in Pharmaceutical Analytical Chemistry, Faculty of Pharmacy, Cairo University, Kasr El-Aini Street, Cairo 11562, Egypt; Pharmaceutical Chemistry Department, Faculty of Pharmacy, Horus University, Horus, 34518, Egypt; Biosensors Research Lab, Zewail City of Science and Technology, 6(th) October City, Giza, 12578, Egypt.<br /><searchLink fieldCode="AU" term="%22Saleh+OA%22">Saleh OA</searchLink>; Medicinal and Pharmaceutical Chemistry Department, Pharmaceutical and Drug Industries Research Institute, National Research Centre, Giza, 12622, Egypt.<br /><searchLink fieldCode="AU" term="%22Hassan+RYA%22">Hassan RYA</searchLink>; Biosensors Research Lab, Zewail City of Science and Technology, 6(th) October City, Giza, 12578, Egypt; Applied Organic Chemistry Department, National Research Centre (NRC), Dokki, Giza, 12622, Egypt.<br /><searchLink fieldCode="AU" term="%22Abd-Rabou+AA%22">Abd-Rabou AA</searchLink>; Hormones Department, Medical Research and Clinical Studies Institute, National Research Centre, Dokki, Giza, Egypt.<br /><searchLink fieldCode="AU" term="%22Badawey+AM%22">Badawey AM</searchLink>; Pharmaceutical Analytical Chemistry Department, Faculty of Pharmacy, Cairo University, Kasr El-Aini Street, Cairo 11562, Egypt. Electronic address: amr.badawey@pharma.cu.edu.eg.<br /><searchLink fieldCode="AU" term="%22Marzouk+HM%22">Marzouk HM</searchLink>; Pharmaceutical Analytical Chemistry Department, Faculty of Pharmacy, Cairo University, Kasr El-Aini Street, Cairo 11562, Egypt. Electronic address: hodaallah.marzouk@pharma.cu.edu.eg.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Elsevier%22">Elsevier </searchLink><i>Country of Publication: </i>Netherlands <i>NLM ID: </i>101139554 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1873-376X (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2215700232%22">15700232 </searchLink><i>NLM ISO Abbreviation: </i>J Chromatogr B Analyt Technol Biomed Life Sci <i>Subsets: </i>MEDLINE
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              Text: 2026 Feb 01
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