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From intravenous to subcutaneous pertuzumab/trastuzumab in breast cancer: Clinical and pharmacoeconomic drivers and barriers to switching.

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Title: From intravenous to subcutaneous pertuzumab/trastuzumab in breast cancer: Clinical and pharmacoeconomic drivers and barriers to switching.
Authors: Gaudio M; IRCCS Humanitas Research Hospital, Rozzano, Milan, Italy.; Department of Biomedical Sciences, Humanitas University, Pieve Emanuele, Milan, Italy., Floreani A; Department of Biomedical Sciences, Humanitas University, Pieve Emanuele, Milan, Italy., Schivardi G; Medical Oncology Department, ASST Spedali Civili of Brescia, Brescia, Italy., Alaimo D; Medical Oncology Unit, Fondazione IRCCS Policlinico San Matteo, Pavia, Italy.; Department of Internal Medicine and Medical Therapy, University of Pavia, Pavia, Italy., Basilico V; Medical Oncology Unit, Istituto Clinico Mater Domini Humanitas, Castellanza, Varese, Italy., Lorenzetti I; Medical Oncology Unit, Istituto Clinico Mater Domini Humanitas, Castellanza, Varese, Italy., Crepaldi C; Medical Oncology Unit, Istituto Clinico Mater Domini Humanitas, Castellanza, Varese, Italy., Tinterri B; IRCCS Humanitas Research Hospital, Rozzano, Milan, Italy.; Department of Biomedical Sciences, Humanitas University, Pieve Emanuele, Milan, Italy., Panzardi A; IRCCS Humanitas Research Hospital, Rozzano, Milan, Italy.; Department of Biomedical Sciences, Humanitas University, Pieve Emanuele, Milan, Italy., Strada D; IRCCS Humanitas Research Hospital, Rozzano, Milan, Italy., Saltalamacchia G; IRCCS Humanitas Research Hospital, Rozzano, Milan, Italy., Jacobs F; IRCCS Humanitas Research Hospital, Rozzano, Milan, Italy.; Department of Biomedical Sciences, Humanitas University, Pieve Emanuele, Milan, Italy., Benvenuti C; IRCCS Humanitas Research Hospital, Rozzano, Milan, Italy.; Department of Biomedical Sciences, Humanitas University, Pieve Emanuele, Milan, Italy., Gerosa R; IRCCS Humanitas Research Hospital, Rozzano, Milan, Italy.; Department of Biomedical Sciences, Humanitas University, Pieve Emanuele, Milan, Italy., Canzian J; IRCCS Humanitas Research Hospital, Rozzano, Milan, Italy.; Department of Biomedical Sciences, Humanitas University, Pieve Emanuele, Milan, Italy., Rodà G; Medical Oncology Unit, Istituto Clinico Mater Domini Humanitas, Castellanza, Varese, Italy., La Verde N; Department of Oncology, Luigi Sacco University Hospital, ASST Fatebenefratelli Sacco, Milan, Italy., Pedersini R; Medical Oncology Department, ASST Spedali Civili of Brescia, Brescia, Italy., Conforti F; Department of Biomedical Sciences, Humanitas University, Pieve Emanuele, Milan, Italy.; Division of Medical Oncology, Humanitas Gavazzeni, Bergamo, Italy., Rizzo G; Medical Oncology Unit, Fondazione IRCCS Policlinico San Matteo, Pavia, Italy.; Department of Internal Medicine and Medical Therapy, University of Pavia, Pavia, Italy., Torrisi R; IRCCS Humanitas Research Hospital, Rozzano, Milan, Italy., Santoro A; IRCCS Humanitas Research Hospital, Rozzano, Milan, Italy.; Department of Biomedical Sciences, Humanitas University, Pieve Emanuele, Milan, Italy., Cortesi PA; Research Centre on Public Health (CESP), University of Milano Bicocca, Villa Serena, Monza, Italy.; Laboratory of Public Health, IRCCS Istituto Auxologico Italiano, Milan, Italy., De Sanctis R; IRCCS Humanitas Research Hospital, Rozzano, Milan, Italy.; Department of Biomedical Sciences, Humanitas University, Pieve Emanuele, Milan, Italy., Zambelli A; Department of Oncology, ASST Papa Giovanni XXIII, Bergamo, Italy.; Department of Medicine and Surgery, University of Milano-Bicocca, Milan, Italy.
Source: Tumori [Tumori] 2026 Feb; Vol. 112 (1), pp. 22-31. Date of Electronic Publication: 2025 Dec 14.
Publication Type: Journal Article; Multicenter Study; Observational Study
Journal Info: Publisher: Sage Publications Country of Publication: United States NLM ID: 0111356 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2038-2529 (Electronic) Linking ISSN: 03008916 NLM ISO Abbreviation: Tumori Subsets: MEDLINE
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  Data: From intravenous to subcutaneous pertuzumab/trastuzumab in breast cancer: Clinical and pharmacoeconomic drivers and barriers to switching.
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  Data: <searchLink fieldCode="AU" term="%22Gaudio+M%22">Gaudio M</searchLink>; IRCCS Humanitas Research Hospital, Rozzano, Milan, Italy.; Department of Biomedical Sciences, Humanitas University, Pieve Emanuele, Milan, Italy.<br /><searchLink fieldCode="AU" term="%22Floreani+A%22">Floreani A</searchLink>; Department of Biomedical Sciences, Humanitas University, Pieve Emanuele, Milan, Italy.<br /><searchLink fieldCode="AU" term="%22Schivardi+G%22">Schivardi G</searchLink>; Medical Oncology Department, ASST Spedali Civili of Brescia, Brescia, Italy.<br /><searchLink fieldCode="AU" term="%22Alaimo+D%22">Alaimo D</searchLink>; Medical Oncology Unit, Fondazione IRCCS Policlinico San Matteo, Pavia, Italy.; Department of Internal Medicine and Medical Therapy, University of Pavia, Pavia, Italy.<br /><searchLink fieldCode="AU" term="%22Basilico+V%22">Basilico V</searchLink>; Medical Oncology Unit, Istituto Clinico Mater Domini Humanitas, Castellanza, Varese, Italy.<br /><searchLink fieldCode="AU" term="%22Lorenzetti+I%22">Lorenzetti I</searchLink>; Medical Oncology Unit, Istituto Clinico Mater Domini Humanitas, Castellanza, Varese, Italy.<br /><searchLink fieldCode="AU" term="%22Crepaldi+C%22">Crepaldi C</searchLink>; Medical Oncology Unit, Istituto Clinico Mater Domini Humanitas, Castellanza, Varese, Italy.<br /><searchLink fieldCode="AU" term="%22Tinterri+B%22">Tinterri B</searchLink>; IRCCS Humanitas Research Hospital, Rozzano, Milan, Italy.; Department of Biomedical Sciences, Humanitas University, Pieve Emanuele, Milan, Italy.<br /><searchLink fieldCode="AU" term="%22Panzardi+A%22">Panzardi A</searchLink>; IRCCS Humanitas Research Hospital, Rozzano, Milan, Italy.; Department of Biomedical Sciences, Humanitas University, Pieve Emanuele, Milan, Italy.<br /><searchLink fieldCode="AU" term="%22Strada+D%22">Strada D</searchLink>; IRCCS Humanitas Research Hospital, Rozzano, Milan, Italy.<br /><searchLink fieldCode="AU" term="%22Saltalamacchia+G%22">Saltalamacchia G</searchLink>; IRCCS Humanitas Research Hospital, Rozzano, Milan, Italy.<br /><searchLink fieldCode="AU" term="%22Jacobs+F%22">Jacobs F</searchLink>; IRCCS Humanitas Research Hospital, Rozzano, Milan, Italy.; Department of Biomedical Sciences, Humanitas University, Pieve Emanuele, Milan, Italy.<br /><searchLink fieldCode="AU" term="%22Benvenuti+C%22">Benvenuti C</searchLink>; IRCCS Humanitas Research Hospital, Rozzano, Milan, Italy.; Department of Biomedical Sciences, Humanitas University, Pieve Emanuele, Milan, Italy.<br /><searchLink fieldCode="AU" term="%22Gerosa+R%22">Gerosa R</searchLink>; IRCCS Humanitas Research Hospital, Rozzano, Milan, Italy.; Department of Biomedical Sciences, Humanitas University, Pieve Emanuele, Milan, Italy.<br /><searchLink fieldCode="AU" term="%22Canzian+J%22">Canzian J</searchLink>; IRCCS Humanitas Research Hospital, Rozzano, Milan, Italy.; Department of Biomedical Sciences, Humanitas University, Pieve Emanuele, Milan, Italy.<br /><searchLink fieldCode="AU" term="%22Rodà+G%22">Rodà G</searchLink>; Medical Oncology Unit, Istituto Clinico Mater Domini Humanitas, Castellanza, Varese, Italy.<br /><searchLink fieldCode="AU" term="%22La+Verde+N%22">La Verde N</searchLink>; Department of Oncology, Luigi Sacco University Hospital, ASST Fatebenefratelli Sacco, Milan, Italy.<br /><searchLink fieldCode="AU" term="%22Pedersini+R%22">Pedersini R</searchLink>; Medical Oncology Department, ASST Spedali Civili of Brescia, Brescia, Italy.<br /><searchLink fieldCode="AU" term="%22Conforti+F%22">Conforti F</searchLink>; Department of Biomedical Sciences, Humanitas University, Pieve Emanuele, Milan, Italy.; Division of Medical Oncology, Humanitas Gavazzeni, Bergamo, Italy.<br /><searchLink fieldCode="AU" term="%22Rizzo+G%22">Rizzo G</searchLink>; Medical Oncology Unit, Fondazione IRCCS Policlinico San Matteo, Pavia, Italy.; Department of Internal Medicine and Medical Therapy, University of Pavia, Pavia, Italy.<br /><searchLink fieldCode="AU" term="%22Torrisi+R%22">Torrisi R</searchLink>; IRCCS Humanitas Research Hospital, Rozzano, Milan, Italy.<br /><searchLink fieldCode="AU" term="%22Santoro+A%22">Santoro A</searchLink>; IRCCS Humanitas Research Hospital, Rozzano, Milan, Italy.; Department of Biomedical Sciences, Humanitas University, Pieve Emanuele, Milan, Italy.<br /><searchLink fieldCode="AU" term="%22Cortesi+PA%22">Cortesi PA</searchLink>; Research Centre on Public Health (CESP), University of Milano Bicocca, Villa Serena, Monza, Italy.; Laboratory of Public Health, IRCCS Istituto Auxologico Italiano, Milan, Italy.<br /><searchLink fieldCode="AU" term="%22De+Sanctis+R%22">De Sanctis R</searchLink>; IRCCS Humanitas Research Hospital, Rozzano, Milan, Italy.; Department of Biomedical Sciences, Humanitas University, Pieve Emanuele, Milan, Italy.<br /><searchLink fieldCode="AU" term="%22Zambelli+A%22">Zambelli A</searchLink>; Department of Oncology, ASST Papa Giovanni XXIII, Bergamo, Italy.; Department of Medicine and Surgery, University of Milano-Bicocca, Milan, Italy.
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  Data: <searchLink fieldCode="JN" term="%220111356%22">Tumori</searchLink> [Tumori] 2026 Feb; Vol. 112 (1), pp. 22-31. <i>Date of Electronic Publication: </i>2025 Dec 14.
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