Biomimetic fractal topography enhances podocyte maturation in vitro.
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| Title: | Biomimetic fractal topography enhances podocyte maturation in vitro. |
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| Authors: | Liu C; Institute of Biomedical Engineering, University of Toronto, Toronto, ON, Canada.; Toronto General Hospital Research Institute, University Health Network, Toronto, ON, Canada., Aggarwal P; Department of Pediatrics, Medical College of Wisconsin, Milwaukee, WI, USA., Wagner KT; Toronto General Hospital Research Institute, University Health Network, Toronto, ON, Canada.; Department of Chemical Engineering and Applied Chemistry, University of Toronto, Toronto, ON, Canada., Landau S; Institute of Biomedical Engineering, University of Toronto, Toronto, ON, Canada.; Toronto General Hospital Research Institute, University Health Network, Toronto, ON, Canada., Cui T; Department of Mechanical and Industrial Engineering, University of Toronto, Toronto, ON, Canada., Song X; Department of Chemical Engineering and Applied Chemistry, University of Toronto, Toronto, ON, Canada., Shamaei L; Department of Mechanical Engineering, University of Alberta, Toronto, ON, Canada., Rafatian N; Institute of Biomedical Engineering, University of Toronto, Toronto, ON, Canada., Zhao Y; Toronto General Hospital Research Institute, University Health Network, Toronto, ON, Canada.; Acceleration Consortium, University of Toronto, Toronto, Canada., Rodriguez-Ramirez S; Department of Medicine, Division of Nephrology, University Health Network, Toronto, ON, Canada.; Ajmera Transplant Centre, University Health Network, Toronto, ON, Canada., Morton K; BioAnalytical Micro-Nano Devices section, National Research Council Canada, Toronto, ON, Canada.; Centre for Research and Applications in Fluidic Technologies, Toronto, ON, Canada., Virlee E; Department of Pediatrics, Medical College of Wisconsin, Milwaukee, WI, USA., Li CY; Department of Chemical Engineering and Applied Chemistry, University of Toronto, Toronto, ON, Canada., Bannerman D; Toronto General Hospital Research Institute, University Health Network, Toronto, ON, Canada.; Department of Chemical Engineering and Applied Chemistry, University of Toronto, Toronto, ON, Canada., Pascual-Gil S; Toronto General Hospital Research Institute, University Health Network, Toronto, ON, Canada., Okhovatian S; Institute of Biomedical Engineering, University of Toronto, Toronto, ON, Canada.; Toronto General Hospital Research Institute, University Health Network, Toronto, ON, Canada., Radisic A; Institute of Biomedical Engineering, University of Toronto, Toronto, ON, Canada., Clotet-Freixas S; Toronto General Hospital Research Institute, University Health Network, Toronto, ON, Canada.; Ajmera Transplant Centre, University Health Network, Toronto, ON, Canada.; Division of Nephrology, McMaster University and St. Joseph's Healthcare, Hamilton, ON, Canada., Veres T; Department of Mechanical and Industrial Engineering, University of Toronto, Toronto, ON, Canada.; BioAnalytical Micro-Nano Devices section, National Research Council Canada, Toronto, ON, Canada.; Centre for Research and Applications in Fluidic Technologies, Toronto, ON, Canada., Sadrzadeh M; Department of Mechanical Engineering, University of Alberta, Toronto, ON, Canada., Filleter T; Department of Mechanical and Industrial Engineering, University of Toronto, Toronto, ON, Canada., Broeckel U; Department of Pediatrics, Medical College of Wisconsin, Milwaukee, WI, USA., Konvalinka A; Toronto General Hospital Research Institute, University Health Network, Toronto, ON, Canada.; Department of Medicine, Division of Nephrology, University Health Network, Toronto, ON, Canada.; Ajmera Transplant Centre, University Health Network, Toronto, ON, Canada.; Institute of Medical Science, University of Toronto, Toronto, ON, Canada.; Department of Laboratory Medicine and Pathobiology, University of Toronto, Toronto, ON, Canada., Radisic M; Institute of Biomedical Engineering, University of Toronto, Toronto, ON, Canada. m.radisic@utoronto.ca.; Toronto General Hospital Research Institute, University Health Network, Toronto, ON, Canada. m.radisic@utoronto.ca.; Department of Chemical Engineering and Applied Chemistry, University of Toronto, Toronto, ON, Canada. m.radisic@utoronto.ca.; Acceleration Consortium, University of Toronto, Toronto, Canada. m.radisic@utoronto.ca.; Centre for Research and Applications in Fluidic Technologies, Toronto, ON, Canada. m.radisic@utoronto.ca.; Institute of Medical Science, University of Toronto, Toronto, ON, Canada. m.radisic@utoronto.ca.; The Heart and Stroke/Richard Lewar Center of Excellence, University of Toronto, Toronto, ON, Canada. m.radisic@utoronto.ca.; Terrence Donnelly Centre for Cellular and Biomolecular Research, University of Toronto, Toronto, ON, Canada. m.radisic@utoronto.ca. |
| Source: | Nature communications [Nat Commun] 2025 Dec 15; Vol. 16 (1), pp. 11116. Date of Electronic Publication: 2025 Dec 15. |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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| ISSN: | 2041-1723 |
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| DOI: | 10.1038/s41467-025-66037-8 |
