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The production of the chemokine CCL2 by corneal sensory neurons initiates anti-viral immunity at the cornea and trigeminal ganglion.

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Title: The production of the chemokine CCL2 by corneal sensory neurons initiates anti-viral immunity at the cornea and trigeminal ganglion.
Authors: Yun H; School of Medicine, Department of Ophthalmology, University of Pittsburgh, Pittsburgh, PA, USA. Electronic address: hoy17@pitt.edu., Moghbeli K; Center for Systems Immunology and Department of Immunology, University of Pittsburgh, Pittsburgh, PA, USA., Gerges PH; Center for Systems Immunology and Department of Immunology, University of Pittsburgh, Pittsburgh, PA, USA., Cisney RN; School of Medicine, Department of Ophthalmology, University of Pittsburgh, Pittsburgh, PA, USA; Department of Microbiology and Immunology, University of Pittsburgh, Pittsburgh, PA, USA., Yoshida M; School of Medicine, Department of Ophthalmology, University of Pittsburgh, Pittsburgh, PA, USA., Hawse WF; Department of Microbiology and Immunology, University of Pittsburgh, Pittsburgh, PA, USA., MacDonald WA; Department of Pediatrics, University of Pittsburgh, Pittsburgh, PA, USA., Bhuiyan SA; Department of Neurology, Brigham and Women's Hospital and Harvard Medical School, Boston, MA 02115, USA., Renthal W; Department of Neurology, Brigham and Women's Hospital and Harvard Medical School, Boston, MA 02115, USA., Sullivan CJ; Department of Neurobiology, University of Pittsburgh, Pittsburgh, PA, USA., Das J; Center for Systems Immunology and Department of Immunology, University of Pittsburgh, Pittsburgh, PA, USA., Kaplan DH; Department of Dermatology, University of Pittsburgh, Pittsburgh, PA, USA., Singh H; Center for Systems Immunology and Department of Immunology, University of Pittsburgh, Pittsburgh, PA, USA., Davis BM; Department of Neurobiology, University of Pittsburgh, Pittsburgh, PA, USA. Electronic address: bmd16@pitt.edu., St Leger AJ; School of Medicine, Department of Ophthalmology, University of Pittsburgh, Pittsburgh, PA, USA; Department of Microbiology and Immunology, University of Pittsburgh, Pittsburgh, PA, USA. Electronic address: anthony.stleger@pitt.edu.
Source: Cell reports [Cell Rep] 2026 Jan 27; Vol. 45 (1), pp. 116693. Date of Electronic Publication: 2025 Dec 16.
Publication Type: Journal Article
Journal Info: Publisher: Cell Press Country of Publication: United States NLM ID: 101573691 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2211-1247 (Electronic) NLM ISO Abbreviation: Cell Rep Subsets: MEDLINE
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  Data: <searchLink fieldCode="AU" term="%22Yun+H%22">Yun H</searchLink>; School of Medicine, Department of Ophthalmology, University of Pittsburgh, Pittsburgh, PA, USA. Electronic address: hoy17@pitt.edu.<br /><searchLink fieldCode="AU" term="%22Moghbeli+K%22">Moghbeli K</searchLink>; Center for Systems Immunology and Department of Immunology, University of Pittsburgh, Pittsburgh, PA, USA.<br /><searchLink fieldCode="AU" term="%22Gerges+PH%22">Gerges PH</searchLink>; Center for Systems Immunology and Department of Immunology, University of Pittsburgh, Pittsburgh, PA, USA.<br /><searchLink fieldCode="AU" term="%22Cisney+RN%22">Cisney RN</searchLink>; School of Medicine, Department of Ophthalmology, University of Pittsburgh, Pittsburgh, PA, USA; Department of Microbiology and Immunology, University of Pittsburgh, Pittsburgh, PA, USA.<br /><searchLink fieldCode="AU" term="%22Yoshida+M%22">Yoshida M</searchLink>; School of Medicine, Department of Ophthalmology, University of Pittsburgh, Pittsburgh, PA, USA.<br /><searchLink fieldCode="AU" term="%22Hawse+WF%22">Hawse WF</searchLink>; Department of Microbiology and Immunology, University of Pittsburgh, Pittsburgh, PA, USA.<br /><searchLink fieldCode="AU" term="%22MacDonald+WA%22">MacDonald WA</searchLink>; Department of Pediatrics, University of Pittsburgh, Pittsburgh, PA, USA.<br /><searchLink fieldCode="AU" term="%22Bhuiyan+SA%22">Bhuiyan SA</searchLink>; Department of Neurology, Brigham and Women's Hospital and Harvard Medical School, Boston, MA 02115, USA.<br /><searchLink fieldCode="AU" term="%22Renthal+W%22">Renthal W</searchLink>; Department of Neurology, Brigham and Women's Hospital and Harvard Medical School, Boston, MA 02115, USA.<br /><searchLink fieldCode="AU" term="%22Sullivan+CJ%22">Sullivan CJ</searchLink>; Department of Neurobiology, University of Pittsburgh, Pittsburgh, PA, USA.<br /><searchLink fieldCode="AU" term="%22Das+J%22">Das J</searchLink>; Center for Systems Immunology and Department of Immunology, University of Pittsburgh, Pittsburgh, PA, USA.<br /><searchLink fieldCode="AU" term="%22Kaplan+DH%22">Kaplan DH</searchLink>; Department of Dermatology, University of Pittsburgh, Pittsburgh, PA, USA.<br /><searchLink fieldCode="AU" term="%22Singh+H%22">Singh H</searchLink>; Center for Systems Immunology and Department of Immunology, University of Pittsburgh, Pittsburgh, PA, USA.<br /><searchLink fieldCode="AU" term="%22Davis+BM%22">Davis BM</searchLink>; Department of Neurobiology, University of Pittsburgh, Pittsburgh, PA, USA. Electronic address: bmd16@pitt.edu.<br /><searchLink fieldCode="AU" term="%22St+Leger+AJ%22">St Leger AJ</searchLink>; School of Medicine, Department of Ophthalmology, University of Pittsburgh, Pittsburgh, PA, USA; Department of Microbiology and Immunology, University of Pittsburgh, Pittsburgh, PA, USA. Electronic address: anthony.stleger@pitt.edu.
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  Data: <searchLink fieldCode="JN" term="%22101573691%22">Cell reports</searchLink> [Cell Rep] 2026 Jan 27; Vol. 45 (1), pp. 116693. <i>Date of Electronic Publication: </i>2025 Dec 16.
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