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Next-Generation Vaccines for Co-Circulating PEDV and TGEV: Integrating Nucleic Acid Platforms, Mucosal Delivery, and AI-Driven Antigen Design.

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Title: Next-Generation Vaccines for Co-Circulating PEDV and TGEV: Integrating Nucleic Acid Platforms, Mucosal Delivery, and AI-Driven Antigen Design.
Authors: Hu X; College of Veterinary Medicine, Jilin Agricultural University, Changchun, 130118, Jilin, China, jlau.edu.cn.; Changchun Veterinary Research Institute, Chinese Academy of Agricultural Sciences, State Key Laboratory of Pathogen and Biosecurity, Key Laboratory of Jilin Province for Zoonosis Prevention and Control, Changchun, 130000, China, caas.cn., Wang Z; Key Laboratory of Special Animal Epidemic Disease, Ministry of Agriculture, Jilin Provincial International Cooperation Key Laboratory for Science and Technology Innovation of Special Animal and Plants, Institute of Special Institute of Special Animal and Plant Sciences, Chinese Academy of Agricultural Sciences, Changchun, 130112, China, caas.cn., Wang S; Changchun Veterinary Research Institute, Chinese Academy of Agricultural Sciences, State Key Laboratory of Pathogen and Biosecurity, Key Laboratory of Jilin Province for Zoonosis Prevention and Control, Changchun, 130000, China, caas.cn., Sun H; College of Veterinary Medicine, Jilin Agricultural University, Changchun, 130118, Jilin, China, jlau.edu.cn.; Changchun Veterinary Research Institute, Chinese Academy of Agricultural Sciences, State Key Laboratory of Pathogen and Biosecurity, Key Laboratory of Jilin Province for Zoonosis Prevention and Control, Changchun, 130000, China, caas.cn., Feng N; Changchun Veterinary Research Institute, Chinese Academy of Agricultural Sciences, State Key Laboratory of Pathogen and Biosecurity, Key Laboratory of Jilin Province for Zoonosis Prevention and Control, Changchun, 130000, China, caas.cn., Li E; Center for Infectious Medicine and Vaccine Research, School of Basic Medicine and Clinical Pharmacy, China Pharmaceutical University, Nanjing, 211198, China, cpu.edu.cn.; Innovation Center for Nucleic Acid Medicine, Institute for Innovative Drug Development and Life Sciences, Wuxi, 214000, China., Xia X; Changchun Veterinary Research Institute, Chinese Academy of Agricultural Sciences, State Key Laboratory of Pathogen and Biosecurity, Key Laboratory of Jilin Province for Zoonosis Prevention and Control, Changchun, 130000, China, caas.cn., Hu G; College of Veterinary Medicine, Jilin Agricultural University, Changchun, 130118, Jilin, China, jlau.edu.cn., Yan F; Changchun Veterinary Research Institute, Chinese Academy of Agricultural Sciences, State Key Laboratory of Pathogen and Biosecurity, Key Laboratory of Jilin Province for Zoonosis Prevention and Control, Changchun, 130000, China, caas.cn., Li B; College of Veterinary Medicine, Jilin Agricultural University, Changchun, 130118, Jilin, China, jlau.edu.cn.; Changchun Veterinary Research Institute, Chinese Academy of Agricultural Sciences, State Key Laboratory of Pathogen and Biosecurity, Key Laboratory of Jilin Province for Zoonosis Prevention and Control, Changchun, 130000, China, caas.cn.; Key Laboratory of Special Animal Epidemic Disease, Ministry of Agriculture, Jilin Provincial International Cooperation Key Laboratory for Science and Technology Innovation of Special Animal and Plants, Institute of Special Institute of Special Animal and Plant Sciences, Chinese Academy of Agricultural Sciences, Changchun, 130112, China, caas.cn.; Center for Infectious Medicine and Vaccine Research, School of Basic Medicine and Clinical Pharmacy, China Pharmaceutical University, Nanjing, 211198, China, cpu.edu.cn.; Innovation Center for Nucleic Acid Medicine, Institute for Innovative Drug Development and Life Sciences, Wuxi, 214000, China.
Source: Transboundary and emerging diseases [Transbound Emerg Dis] 2025 Dec 04; Vol. 2025, pp. 2014296. Date of Electronic Publication: 2025 Dec 04 (Print Publication: 2025).
Publication Type: Journal Article; Review
Journal Info: Publisher: Blackwell Verlag Country of Publication: Germany NLM ID: 101319538 Publication Model: eCollection Cited Medium: Internet ISSN: 1865-1682 (Electronic) Linking ISSN: 18651674 NLM ISO Abbreviation: Transbound Emerg Dis Subsets: MEDLINE
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  Data: Next-Generation Vaccines for Co-Circulating PEDV and TGEV: Integrating Nucleic Acid Platforms, Mucosal Delivery, and AI-Driven Antigen Design.
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  Data: <searchLink fieldCode="AU" term="%22Hu+X%22">Hu X</searchLink>; College of Veterinary Medicine, Jilin Agricultural University, Changchun, 130118, Jilin, China, jlau.edu.cn.; Changchun Veterinary Research Institute, Chinese Academy of Agricultural Sciences, State Key Laboratory of Pathogen and Biosecurity, Key Laboratory of Jilin Province for Zoonosis Prevention and Control, Changchun, 130000, China, caas.cn.<br /><searchLink fieldCode="AU" term="%22Wang+Z%22">Wang Z</searchLink>; Key Laboratory of Special Animal Epidemic Disease, Ministry of Agriculture, Jilin Provincial International Cooperation Key Laboratory for Science and Technology Innovation of Special Animal and Plants, Institute of Special Institute of Special Animal and Plant Sciences, Chinese Academy of Agricultural Sciences, Changchun, 130112, China, caas.cn.<br /><searchLink fieldCode="AU" term="%22Wang+S%22">Wang S</searchLink>; Changchun Veterinary Research Institute, Chinese Academy of Agricultural Sciences, State Key Laboratory of Pathogen and Biosecurity, Key Laboratory of Jilin Province for Zoonosis Prevention and Control, Changchun, 130000, China, caas.cn.<br /><searchLink fieldCode="AU" term="%22Sun+H%22">Sun H</searchLink>; College of Veterinary Medicine, Jilin Agricultural University, Changchun, 130118, Jilin, China, jlau.edu.cn.; Changchun Veterinary Research Institute, Chinese Academy of Agricultural Sciences, State Key Laboratory of Pathogen and Biosecurity, Key Laboratory of Jilin Province for Zoonosis Prevention and Control, Changchun, 130000, China, caas.cn.<br /><searchLink fieldCode="AU" term="%22Feng+N%22">Feng N</searchLink>; Changchun Veterinary Research Institute, Chinese Academy of Agricultural Sciences, State Key Laboratory of Pathogen and Biosecurity, Key Laboratory of Jilin Province for Zoonosis Prevention and Control, Changchun, 130000, China, caas.cn.<br /><searchLink fieldCode="AU" term="%22Li+E%22">Li E</searchLink>; Center for Infectious Medicine and Vaccine Research, School of Basic Medicine and Clinical Pharmacy, China Pharmaceutical University, Nanjing, 211198, China, cpu.edu.cn.; Innovation Center for Nucleic Acid Medicine, Institute for Innovative Drug Development and Life Sciences, Wuxi, 214000, China.<br /><searchLink fieldCode="AU" term="%22Xia+X%22">Xia X</searchLink>; Changchun Veterinary Research Institute, Chinese Academy of Agricultural Sciences, State Key Laboratory of Pathogen and Biosecurity, Key Laboratory of Jilin Province for Zoonosis Prevention and Control, Changchun, 130000, China, caas.cn.<br /><searchLink fieldCode="AU" term="%22Hu+G%22">Hu G</searchLink>; College of Veterinary Medicine, Jilin Agricultural University, Changchun, 130118, Jilin, China, jlau.edu.cn.<br /><searchLink fieldCode="AU" term="%22Yan+F%22">Yan F</searchLink>; Changchun Veterinary Research Institute, Chinese Academy of Agricultural Sciences, State Key Laboratory of Pathogen and Biosecurity, Key Laboratory of Jilin Province for Zoonosis Prevention and Control, Changchun, 130000, China, caas.cn.<br /><searchLink fieldCode="AU" term="%22Li+B%22">Li B</searchLink>; College of Veterinary Medicine, Jilin Agricultural University, Changchun, 130118, Jilin, China, jlau.edu.cn.; Changchun Veterinary Research Institute, Chinese Academy of Agricultural Sciences, State Key Laboratory of Pathogen and Biosecurity, Key Laboratory of Jilin Province for Zoonosis Prevention and Control, Changchun, 130000, China, caas.cn.; Key Laboratory of Special Animal Epidemic Disease, Ministry of Agriculture, Jilin Provincial International Cooperation Key Laboratory for Science and Technology Innovation of Special Animal and Plants, Institute of Special Institute of Special Animal and Plant Sciences, Chinese Academy of Agricultural Sciences, Changchun, 130112, China, caas.cn.; Center for Infectious Medicine and Vaccine Research, School of Basic Medicine and Clinical Pharmacy, China Pharmaceutical University, Nanjing, 211198, China, cpu.edu.cn.; Innovation Center for Nucleic Acid Medicine, Institute for Innovative Drug Development and Life Sciences, Wuxi, 214000, China.
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      – TitleFull: Next-Generation Vaccines for Co-Circulating PEDV and TGEV: Integrating Nucleic Acid Platforms, Mucosal Delivery, and AI-Driven Antigen Design.
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