Efficacy of isoniazid in paediatric tuberculosis: an individual participant data meta-analysis.
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| Title: | Efficacy of isoniazid in paediatric tuberculosis: an individual participant data meta-analysis. |
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| Authors: | Béranger A; Department of Bioengineering and Therapeutic Sciences, University of California San Francisco, San Francisco, CA, USA.; UCSF Center for Tuberculosis, University of California San Francisco, San Francisco, CA, USA.; Université Paris Cité, INSERM, UMR1343, Pharmacologie et Evaluation des Thérapeutiques chez l'Enfant et la Femme Enceinte, Paris, France.; Réanimation et Soins Intensifs Polyvalents Pédiatriques - SMUR Pédiatrique, AP-HP.Centre - Université de Paris Cité, Hôpital Necker Enfants Malades, Paris, France.; A. Béranger and B.P. Solans are equal contributors to this work and designated as co-first authors., Solans BP; Department of Bioengineering and Therapeutic Sciences, University of California San Francisco, San Francisco, CA, USA.; UCSF Center for Tuberculosis, University of California San Francisco, San Francisco, CA, USA.; A. Béranger and B.P. Solans are equal contributors to this work and designated as co-first authors., Miyakawa R; Department of Bioengineering and Therapeutic Sciences, University of California San Francisco, San Francisco, CA, USA.; UCSF Center for Tuberculosis, University of California San Francisco, San Francisco, CA, USA., McIlleron H; Division of Clinical Pharmacology, Department of Medicine, University of Cape Town, Cape Town, South Africa., Tarning J; Mahidol-Oxford Tropical Medicine Research Unit, Faculty of Tropical Medicine, Mahidol University, Bangkok, Thailand.; Centre for Tropical Medicine and Global Health, Nuffield Department of Medicine, University of Oxford, Oxford, UK., Shah I; Pediatric DR-TB Center of Excellence (State), Department of Pediatric Infectious Diseases, B.J. Wadia Hospital for Children, Mumbai, India., Aruldhas BW; Department of Pharmacology and Clinical Pharmacology, Christian Medical College, Vellore, India., Mathew BS; Department of Pharmacology and Clinical Pharmacology, Christian Medical College, Vellore, India., Kwara A; Department of Medicine, College of Medicine, University of Florida, Gainesville, FL, USA., Peloquin CA; Department of Pharmacotherapy and Translational Research, College of Pharmacy, University of Florida, Gainesville, FL, USA., Mukherjee A; Department of Pediatrics, All India Institute of Medical Sciences, Ansari Nagar, India., Lodha R; Department of Pediatrics, All India Institute of Medical Sciences, Ansari Nagar, India., Denti P; Division of Clinical Pharmacology, Department of Medicine, University of Cape Town, Cape Town, South Africa., Capparelli EV; Skaggs School of Pharmacy and Pharmaceutical Sciences, University of California San Diego, La Jolla, CA, USA.; Pediatrics Department, Rady Children's Hospital San Diego, University of California San Diego, La Jolla, CA, USA., Kiser JJ; Department of Pharmaceutical Sciences, Skaggs School of Pharmacy and Pharmaceutical Sciences, University of Colorado Anschutz, Aurora, CO, USA., Bekker A; Family Centre for Research with Ubuntu, Department of Paediatric and Child Health, Stellenbosch University, Cape Town, South Africa., Chabala C; Department of Paediatrics and Child Health, School of Medicine, University of Zambia, Lusaka, Zambia.; University Teaching Hospital, Children's Hospital, Lusaka, Zambia., Choo L; Medical Research Council Clinical Trials Unit, University College London, London, UK., Turkova A; Medical Research Council Clinical Trials Unit, University College London, London, UK., Gafar F; Unit of PharmacoTherapy, -Epidemiology and -Economics, Groningen Research Institute of Pharmacy, University of Groningen, Groningen, The Netherlands.; Department of Biomedical Sciences, Faculty of Medicine, Universitas Padjadjaran, Bandung, Indonesia.; Respiratory Epidemiology and Clinical Research Unit, Centre for Outcomes Research and Evaluation, Research Institute of the McGill University Health Centre, Montreal, QC, Canada.; McGill International TB Centre, McGill University, Montreal, QC, Canada., Ruslami R; Department of Biomedical Sciences, Faculty of Medicine, Universitas Padjadjaran, Bandung, Indonesia.; McGill International TB Centre, McGill University, Montreal, QC, Canada., Nataprawira HM; Division of Pediatric Respirology, Department of Child Health, Hasan Sadikin Hospital, Faculty of Medicine, Universitas Padjadjaran, Bandung, Indonesia., Heysell SK; Division of Infectious Diseases and International Health, University of Virginia, Charlottesville, VA, USA., Thomas TA; Division of Infectious Diseases and International Health, University of Virginia, Charlottesville, VA, USA., Velpandian T; Department of Ocular Pharmacology and Pharmacy, Dr. Rajendra Prasad Centre for Ophthalmic Sciences, All India Institute of Medical Sciences, New Delhi, India., Day JN; Department of Clinical Microbiology and Infection, Royal Devon and Exeter University Hospital NHS Trust, Exeter, UK., Bang ND; Pham Ngoc Thach Hospital for Tuberculosis and Lung Disease, Ho Chi Minh City, Vietnam., Dooley K; Division of Infectious Diseases, Vanderbilt University Medical Center, Nashville, TN, USA., Savic RM; Department of Bioengineering and Therapeutic Sciences, University of California San Francisco, San Francisco, CA, USA rada.savic@ucsf.edu.; UCSF Center for Tuberculosis, University of California San Francisco, San Francisco, CA, USA. |
| Source: | The European respiratory journal [Eur Respir J] 2026 Mar 05; Vol. 67 (3). Date of Electronic Publication: 2026 Mar 05 (Print Publication: 2026). |
| Publication Type: | Journal Article; Meta-Analysis |
| Journal Info: | Publisher: European Respiratory Society Country of Publication: England NLM ID: 8803460 Publication Model: Electronic-Print Cited Medium: Internet ISSN: 1399-3003 (Electronic) Linking ISSN: 09031936 NLM ISO Abbreviation: Eur Respir J Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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