Effectiveness and safety of prasugrel- versus clopidogrel-based dual antiplatelet therapy for acute ischemic stroke.

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Title: Effectiveness and safety of prasugrel- versus clopidogrel-based dual antiplatelet therapy for acute ischemic stroke.
Authors: Nakashima S; Department of Neurology, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan., Aso S; Department of Health Services Research, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan., Yasunaga H; Department of Clinical Epidemiology and Health Economics, School of Public Health, The University of Tokyo, Tokyo, Japan., Sato K; Unit for Early and Exploratory Development, The University of Tokyo Hospital, Tokyo, Japan; Dementia Inclusion and Therapeutics, The University of Tokyo Hospital, Tokyo, Japan., Niimi Y; Unit for Early and Exploratory Development, The University of Tokyo Hospital, Tokyo, Japan; Dementia Inclusion and Therapeutics, The University of Tokyo Hospital, Tokyo, Japan., Isogai T; Department of Health Services Research, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan; Department of Cardiology, Tokyo Metropolitan Tama Medical Center, Tokyo, Japan., Matsui H; Department of Clinical Epidemiology and Health Economics, School of Public Health, The University of Tokyo, Tokyo, Japan., Fushimi K; Department of Health Policy and Informatics, Institute of Science Tokyo Graduate School, Tokyo, Japan., Toda T; Department of Neurology, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan., Kodama S; Department of Neurology, The University of Iowa Hospitals and Clinics, Iowa, United States. Electronic address: satoshi-kodama@uiowa.edu.
Source: Journal of the neurological sciences [J Neurol Sci] 2026 Jan 15; Vol. 480, pp. 125695. Date of Electronic Publication: 2025 Dec 11.
Publication Type: Journal Article; Comparative Study
Journal Info: Publisher: Elsevier Country of Publication: Netherlands NLM ID: 0375403 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1878-5883 (Electronic) Linking ISSN: 0022510X NLM ISO Abbreviation: J Neurol Sci Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Effectiveness and safety of prasugrel- versus clopidogrel-based dual antiplatelet therapy for acute ischemic stroke.
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  Data: <searchLink fieldCode="AU" term="%22Nakashima+S%22">Nakashima S</searchLink>; Department of Neurology, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan.<br /><searchLink fieldCode="AU" term="%22Aso+S%22">Aso S</searchLink>; Department of Health Services Research, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan.<br /><searchLink fieldCode="AU" term="%22Yasunaga+H%22">Yasunaga H</searchLink>; Department of Clinical Epidemiology and Health Economics, School of Public Health, The University of Tokyo, Tokyo, Japan.<br /><searchLink fieldCode="AU" term="%22Sato+K%22">Sato K</searchLink>; Unit for Early and Exploratory Development, The University of Tokyo Hospital, Tokyo, Japan; Dementia Inclusion and Therapeutics, The University of Tokyo Hospital, Tokyo, Japan.<br /><searchLink fieldCode="AU" term="%22Niimi+Y%22">Niimi Y</searchLink>; Unit for Early and Exploratory Development, The University of Tokyo Hospital, Tokyo, Japan; Dementia Inclusion and Therapeutics, The University of Tokyo Hospital, Tokyo, Japan.<br /><searchLink fieldCode="AU" term="%22Isogai+T%22">Isogai T</searchLink>; Department of Health Services Research, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan; Department of Cardiology, Tokyo Metropolitan Tama Medical Center, Tokyo, Japan.<br /><searchLink fieldCode="AU" term="%22Matsui+H%22">Matsui H</searchLink>; Department of Clinical Epidemiology and Health Economics, School of Public Health, The University of Tokyo, Tokyo, Japan.<br /><searchLink fieldCode="AU" term="%22Fushimi+K%22">Fushimi K</searchLink>; Department of Health Policy and Informatics, Institute of Science Tokyo Graduate School, Tokyo, Japan.<br /><searchLink fieldCode="AU" term="%22Toda+T%22">Toda T</searchLink>; Department of Neurology, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan.<br /><searchLink fieldCode="AU" term="%22Kodama+S%22">Kodama S</searchLink>; Department of Neurology, The University of Iowa Hospitals and Clinics, Iowa, United States. Electronic address: satoshi-kodama@uiowa.edu.
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  Data: <searchLink fieldCode="JN" term="%220375403%22">Journal of the neurological sciences</searchLink> [J Neurol Sci] 2026 Jan 15; Vol. 480, pp. 125695. <i>Date of Electronic Publication: </i>2025 Dec 11.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Elsevier%22">Elsevier </searchLink><i>Country of Publication: </i>Netherlands <i>NLM ID: </i>0375403 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1878-5883 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%220022510X%22">0022510X </searchLink><i>NLM ISO Abbreviation: </i>J Neurol Sci <i>Subsets: </i>MEDLINE
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              Text: 2026 Jan 15
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