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Vincristine-induced brain toxicity is reduced with prevention of peripheral axon degeneration in Sarm1 knockout mice.

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Title: Vincristine-induced brain toxicity is reduced with prevention of peripheral axon degeneration in Sarm1 knockout mice.
Authors: Yeung J; Mouse Imaging Centre, Hospital for Sick Children, 25 Orde Street, Toronto, ON, M5T 3H7, Canada. jonas.yeung@sickkids.ca.; Translational Medicine, Hospital for Sick Children Research Institute, Toronto, ON, Canada. jonas.yeung@sickkids.ca.; Department of Medical Biophysics, University of Toronto, Toronto, ON, Canada. jonas.yeung@sickkids.ca., Hsu P; Neuroscience and Mental Health, Hospital for Sick Children Research Institute, Toronto, ON, Canada., Mak J; Neuroscience and Mental Health, Hospital for Sick Children Research Institute, Toronto, ON, Canada.; Department of Physiology, University of Toronto, Toronto, ON, Canada., Darbandi A; Nanoscale Biomedical Imaging Facility, Hospital for Sick Children, Toronto, ON, Canada., Wheeler AL; Neuroscience and Mental Health, Hospital for Sick Children Research Institute, Toronto, ON, Canada.; Department of Physiology, University of Toronto, Toronto, ON, Canada., Weksberg R; Department of Pediatrics, University of Toronto, Toronto, ON, Canada.; Institutes of Medical Science, University of Toronto, Toronto, ON, Canada., Guger SL; Department of Psychology, Hospital for Sick Children, Toronto, ON, Canada., Schachar RJ; Institutes of Medical Science, University of Toronto, Toronto, ON, Canada.; Department of Psychiatry (Emeritus), University of Toronto, Toronto, ON, Canada., Ito S; Translational Medicine, Hospital for Sick Children Research Institute, Toronto, ON, Canada.; Clinical Pharmacology and Toxicology, Hospital for Sick Children, Toronto, ON, Canada.; Department of Pharmacology and Toxicology, University of Toronto, Toronto, ON, Canada., Hitzler J; Department of Pediatrics, University of Toronto, Toronto, ON, Canada.; Institutes of Medical Science, University of Toronto, Toronto, ON, Canada.; Division of Haematology/Oncology, Hospital for Sick Children, Toronto, ON, Canada., Nieman BJ; Mouse Imaging Centre, Hospital for Sick Children, 25 Orde Street, Toronto, ON, M5T 3H7, Canada.; Translational Medicine, Hospital for Sick Children Research Institute, Toronto, ON, Canada.; Department of Medical Biophysics, University of Toronto, Toronto, ON, Canada.
Source: Acta neuropathologica communications [Acta Neuropathol Commun] 2025 Dec 19; Vol. 13 (1), pp. 254. Date of Electronic Publication: 2025 Dec 19.
Publication Type: Journal Article
Journal Info: Publisher: BioMed Central Country of Publication: England NLM ID: 101610673 Publication Model: Electronic Cited Medium: Internet ISSN: 2051-5960 (Electronic) Linking ISSN: 20515960 NLM ISO Abbreviation: Acta Neuropathol Commun Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Vincristine-induced brain toxicity is reduced with prevention of peripheral axon degeneration in Sarm1 knockout mice.
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  Data: <searchLink fieldCode="AU" term="%22Yeung+J%22">Yeung J</searchLink>; Mouse Imaging Centre, Hospital for Sick Children, 25 Orde Street, Toronto, ON, M5T 3H7, Canada. jonas.yeung@sickkids.ca.; Translational Medicine, Hospital for Sick Children Research Institute, Toronto, ON, Canada. jonas.yeung@sickkids.ca.; Department of Medical Biophysics, University of Toronto, Toronto, ON, Canada. jonas.yeung@sickkids.ca.<br /><searchLink fieldCode="AU" term="%22Hsu+P%22">Hsu P</searchLink>; Neuroscience and Mental Health, Hospital for Sick Children Research Institute, Toronto, ON, Canada.<br /><searchLink fieldCode="AU" term="%22Mak+J%22">Mak J</searchLink>; Neuroscience and Mental Health, Hospital for Sick Children Research Institute, Toronto, ON, Canada.; Department of Physiology, University of Toronto, Toronto, ON, Canada.<br /><searchLink fieldCode="AU" term="%22Darbandi+A%22">Darbandi A</searchLink>; Nanoscale Biomedical Imaging Facility, Hospital for Sick Children, Toronto, ON, Canada.<br /><searchLink fieldCode="AU" term="%22Wheeler+AL%22">Wheeler AL</searchLink>; Neuroscience and Mental Health, Hospital for Sick Children Research Institute, Toronto, ON, Canada.; Department of Physiology, University of Toronto, Toronto, ON, Canada.<br /><searchLink fieldCode="AU" term="%22Weksberg+R%22">Weksberg R</searchLink>; Department of Pediatrics, University of Toronto, Toronto, ON, Canada.; Institutes of Medical Science, University of Toronto, Toronto, ON, Canada.<br /><searchLink fieldCode="AU" term="%22Guger+SL%22">Guger SL</searchLink>; Department of Psychology, Hospital for Sick Children, Toronto, ON, Canada.<br /><searchLink fieldCode="AU" term="%22Schachar+RJ%22">Schachar RJ</searchLink>; Institutes of Medical Science, University of Toronto, Toronto, ON, Canada.; Department of Psychiatry (Emeritus), University of Toronto, Toronto, ON, Canada.<br /><searchLink fieldCode="AU" term="%22Ito+S%22">Ito S</searchLink>; Translational Medicine, Hospital for Sick Children Research Institute, Toronto, ON, Canada.; Clinical Pharmacology and Toxicology, Hospital for Sick Children, Toronto, ON, Canada.; Department of Pharmacology and Toxicology, University of Toronto, Toronto, ON, Canada.<br /><searchLink fieldCode="AU" term="%22Hitzler+J%22">Hitzler J</searchLink>; Department of Pediatrics, University of Toronto, Toronto, ON, Canada.; Institutes of Medical Science, University of Toronto, Toronto, ON, Canada.; Division of Haematology/Oncology, Hospital for Sick Children, Toronto, ON, Canada.<br /><searchLink fieldCode="AU" term="%22Nieman+BJ%22">Nieman BJ</searchLink>; Mouse Imaging Centre, Hospital for Sick Children, 25 Orde Street, Toronto, ON, M5T 3H7, Canada.; Translational Medicine, Hospital for Sick Children Research Institute, Toronto, ON, Canada.; Department of Medical Biophysics, University of Toronto, Toronto, ON, Canada.
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  Data: <searchLink fieldCode="JN" term="%22101610673%22">Acta neuropathologica communications</searchLink> [Acta Neuropathol Commun] 2025 Dec 19; Vol. 13 (1), pp. 254. <i>Date of Electronic Publication: </i>2025 Dec 19.
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              Text: 2025 Dec 19
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