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Efficacy and Safety of Once-Weekly Lonapegsomatropin in Adults With Growth Hormone Deficiency: foresiGHt Trial Results.

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Title: Efficacy and Safety of Once-Weekly Lonapegsomatropin in Adults With Growth Hormone Deficiency: foresiGHt Trial Results.
Authors: Biller BMK; Neuroendocrine and Pituitary Tumor Clinical Center, Massachusetts General Hospital and Harvard Medical School, Boston, MA 02114, USA., Gilis-Januszewska A; Department of Endocrinology, Jagiellonian University, Medical College, 30-688 Kraków, Poland., Doknic M; University Clinical Center of Serbia, Medical Faculty University, 11000 Belgrade, Serbia., Pico AM; Clinical Medicine, Alicante Institute for Health and Biomedical Research (ISABIAL), 03202 Elche, Alicante, Spain., Fleseriu M; Department of Medicine and Neurological Surgery, Pituitary Center, Oregon Health and Science University, Portland, OR 97239, USA., Raverot G; Department of Endocrinology, Hospices Civils de Lyon, 69 500 Lyon Cedex 03, France., Isidori AM; Department of Experimental Medicine, Sapienza University of Rome, 00185 Rome, Italy., Takahashi Y; Nara Medical University, Department of Diabetes and Endocrinology, Kashihara, Nara 634-8521, Japan., Garcia JM; Department of Medicine, University of Washington/GRECC, Puget Sound VA, Seattle, WA 98108, USA., Silverstein JM; Division of Endocrinology, Metabolism & Lipid Research, Washington University School of Medicine, St Louis, MO 63110, USA., Bancos I; Division of Endocrinology, Diabetes, Metabolism and Nutrition, Mayo Clinic, Rochester, MN 55902, USA., Fukuoka H; Division of Diabetes and Endocrinology, Kobe University Hospital, Kobe 650-0017, Japan., Huang E; Endocrine and Rare Disease Medical Sciences, Ascendis Pharma, Inc., Palo Alto, CA 94304, USA., Kang J; Endocrine and Rare Disease Medical Sciences, Ascendis Pharma, Inc., Palo Alto, CA 94304, USA., Komirenko AS; Endocrine and Rare Disease Medical Sciences, Ascendis Pharma, Inc., Palo Alto, CA 94304, USA., Domrzalski L; Endocrine and Rare Disease Medical Sciences, Ascendis Pharma, Inc., Palo Alto, CA 94304, USA., Shu AD; Endocrine and Rare Disease Medical Sciences, Ascendis Pharma, Inc., Palo Alto, CA 94304, USA., Beckert M; Endocrine and Rare Disease Medical Sciences, Ascendis Pharma A/S, 2900 Hellerup, Denmark., Yuen KCJ; Department of Neuroendocrinology and Neurosurgery, Barrow Neurological Institute, University of Arizona College of Medicine and Creighton University School of Medicine, Phoenix, AZ 85013, USA.
Source: The Journal of clinical endocrinology and metabolism [J Clin Endocrinol Metab] 2026 May 19; Vol. 111 (6), pp. 1640-1650.
Publication Type: Journal Article; Randomized Controlled Trial; Multicenter Study
Journal Info: Publisher: Oxford University Press Country of Publication: United States NLM ID: 0375362 Publication Model: Print Cited Medium: Internet ISSN: 1945-7197 (Electronic) Linking ISSN: 0021972X NLM ISO Abbreviation: J Clin Endocrinol Metab Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Efficacy and Safety of Once-Weekly Lonapegsomatropin in Adults With Growth Hormone Deficiency: foresiGHt Trial Results.
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  Data: <searchLink fieldCode="AU" term="%22Biller+BMK%22">Biller BMK</searchLink>; Neuroendocrine and Pituitary Tumor Clinical Center, Massachusetts General Hospital and Harvard Medical School, Boston, MA 02114, USA.<br /><searchLink fieldCode="AU" term="%22Gilis-Januszewska+A%22">Gilis-Januszewska A</searchLink>; Department of Endocrinology, Jagiellonian University, Medical College, 30-688 Kraków, Poland.<br /><searchLink fieldCode="AU" term="%22Doknic+M%22">Doknic M</searchLink>; University Clinical Center of Serbia, Medical Faculty University, 11000 Belgrade, Serbia.<br /><searchLink fieldCode="AU" term="%22Pico+AM%22">Pico AM</searchLink>; Clinical Medicine, Alicante Institute for Health and Biomedical Research (ISABIAL), 03202 Elche, Alicante, Spain.<br /><searchLink fieldCode="AU" term="%22Fleseriu+M%22">Fleseriu M</searchLink>; Department of Medicine and Neurological Surgery, Pituitary Center, Oregon Health and Science University, Portland, OR 97239, USA.<br /><searchLink fieldCode="AU" term="%22Raverot+G%22">Raverot G</searchLink>; Department of Endocrinology, Hospices Civils de Lyon, 69 500 Lyon Cedex 03, France.<br /><searchLink fieldCode="AU" term="%22Isidori+AM%22">Isidori AM</searchLink>; Department of Experimental Medicine, Sapienza University of Rome, 00185 Rome, Italy.<br /><searchLink fieldCode="AU" term="%22Takahashi+Y%22">Takahashi Y</searchLink>; Nara Medical University, Department of Diabetes and Endocrinology, Kashihara, Nara 634-8521, Japan.<br /><searchLink fieldCode="AU" term="%22Garcia+JM%22">Garcia JM</searchLink>; Department of Medicine, University of Washington/GRECC, Puget Sound VA, Seattle, WA 98108, USA.<br /><searchLink fieldCode="AU" term="%22Silverstein+JM%22">Silverstein JM</searchLink>; Division of Endocrinology, Metabolism & Lipid Research, Washington University School of Medicine, St Louis, MO 63110, USA.<br /><searchLink fieldCode="AU" term="%22Bancos+I%22">Bancos I</searchLink>; Division of Endocrinology, Diabetes, Metabolism and Nutrition, Mayo Clinic, Rochester, MN 55902, USA.<br /><searchLink fieldCode="AU" term="%22Fukuoka+H%22">Fukuoka H</searchLink>; Division of Diabetes and Endocrinology, Kobe University Hospital, Kobe 650-0017, Japan.<br /><searchLink fieldCode="AU" term="%22Huang+E%22">Huang E</searchLink>; Endocrine and Rare Disease Medical Sciences, Ascendis Pharma, Inc., Palo Alto, CA 94304, USA.<br /><searchLink fieldCode="AU" term="%22Kang+J%22">Kang J</searchLink>; Endocrine and Rare Disease Medical Sciences, Ascendis Pharma, Inc., Palo Alto, CA 94304, USA.<br /><searchLink fieldCode="AU" term="%22Komirenko+AS%22">Komirenko AS</searchLink>; Endocrine and Rare Disease Medical Sciences, Ascendis Pharma, Inc., Palo Alto, CA 94304, USA.<br /><searchLink fieldCode="AU" term="%22Domrzalski+L%22">Domrzalski L</searchLink>; Endocrine and Rare Disease Medical Sciences, Ascendis Pharma, Inc., Palo Alto, CA 94304, USA.<br /><searchLink fieldCode="AU" term="%22Shu+AD%22">Shu AD</searchLink>; Endocrine and Rare Disease Medical Sciences, Ascendis Pharma, Inc., Palo Alto, CA 94304, USA.<br /><searchLink fieldCode="AU" term="%22Beckert+M%22">Beckert M</searchLink>; Endocrine and Rare Disease Medical Sciences, Ascendis Pharma A/S, 2900 Hellerup, Denmark.<br /><searchLink fieldCode="AU" term="%22Yuen+KCJ%22">Yuen KCJ</searchLink>; Department of Neuroendocrinology and Neurosurgery, Barrow Neurological Institute, University of Arizona College of Medicine and Creighton University School of Medicine, Phoenix, AZ 85013, USA.
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  Data: <searchLink fieldCode="JN" term="%220375362%22">The Journal of clinical endocrinology and metabolism</searchLink> [J Clin Endocrinol Metab] 2026 May 19; Vol. 111 (6), pp. 1640-1650.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Oxford+University+Press%22">Oxford University Press </searchLink><i>Country of Publication: </i>United States <i>NLM ID: </i>0375362 <i>Publication Model: </i>Print <i>Cited Medium: </i>Internet <i>ISSN: </i>1945-7197 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%220021972X%22">0021972X </searchLink><i>NLM ISO Abbreviation: </i>J Clin Endocrinol Metab <i>Subsets: </i>MEDLINE
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