Development of synovial sarcoma organoids exhibiting ferroptosis resistance despite low malic enzyme 1 expression.
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| Title: | Development of synovial sarcoma organoids exhibiting ferroptosis resistance despite low malic enzyme 1 expression. |
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| Authors: | Wakamatsu T; Department of Musculoskeletal Oncology Service, Osaka International Cancer Institute, 3-1-69 Otemae, Chuo-Ku, Osaka, 541-8567, Japan. evolutionhhh49@yahoo.co.jp.; Department of Orthopaedic Surgery, Osaka University Graduate School of Medicine, 2-2 Yamadaoka, Suita, Osaka, 565-0871, Japan. evolutionhhh49@yahoo.co.jp., Yamada Y; Department of Musculoskeletal Oncology Service, Osaka International Cancer Institute, 3-1-69 Otemae, Chuo-Ku, Osaka, 541-8567, Japan.; Department of Orthopaedic Surgery, Osaka University Graduate School of Medicine, 2-2 Yamadaoka, Suita, Osaka, 565-0871, Japan., Yoshida K; Next-Generation Precision Medicine Research Center, Osaka International Cancer Institute, 3-1-69 Otemae, Chuo-Ku, Osaka, 541-8567, Japan., Matsuoka Y; Next-Generation Precision Medicine Research Center, Osaka International Cancer Institute, 3-1-69 Otemae, Chuo-Ku, Osaka, 541-8567, Japan., Sasagawa S; Molecular Biology Laboratory, Research Institute, Nozaki Tokushukai Hospital, Tanigawa 2-10-50, Daito, Osaka, 574-0074, Japan., Nagamine N; Department of Musculoskeletal Oncology Service, Osaka International Cancer Institute, 3-1-69 Otemae, Chuo-Ku, Osaka, 541-8567, Japan., Shizuma K; Department of Cancer Immunotherapy, Research Center, Osaka International Cancer Institute, 3-1-69 Otemae, Chuo-Ku, Osaka, 541-8567, Japan., Suzuki R; Department of Musculoskeletal Oncology Service, Osaka International Cancer Institute, 3-1-69 Otemae, Chuo-Ku, Osaka, 541-8567, Japan.; Department of Orthopaedic Surgery, Osaka University Graduate School of Medicine, 2-2 Yamadaoka, Suita, Osaka, 565-0871, Japan., Tamiya H; Department of Musculoskeletal Oncology Service, Osaka International Cancer Institute, 3-1-69 Otemae, Chuo-Ku, Osaka, 541-8567, Japan.; Department of Orthopaedic Surgery, Osaka University Graduate School of Medicine, 2-2 Yamadaoka, Suita, Osaka, 565-0871, Japan., Imura Y; Department of Orthopaedic Surgery, Osaka University Graduate School of Medicine, 2-2 Yamadaoka, Suita, Osaka, 565-0871, Japan., Nakai S; Department of Orthopaedic Surgery, Osaka University Graduate School of Medicine, 2-2 Yamadaoka, Suita, Osaka, 565-0871, Japan., Okada S; Department of Orthopaedic Surgery, Osaka University Graduate School of Medicine, 2-2 Yamadaoka, Suita, Osaka, 565-0871, Japan., Yagi T; Department of Musculoskeletal Oncology Service, Osaka International Cancer Institute, 3-1-69 Otemae, Chuo-Ku, Osaka, 541-8567, Japan., Yoshida KI; Department of Diagnostic Pathology and Cytology, Osaka International Cancer Institute, 3-1-69 Otemae, Chuo-Ku, Osaka, 541-8567, Japan., Kakunaga S; Department of Musculoskeletal Oncology Service, Osaka International Cancer Institute, 3-1-69 Otemae, Chuo-Ku, Osaka, 541-8567, Japan.; Department of Orthopaedic Surgery, Osaka University Graduate School of Medicine, 2-2 Yamadaoka, Suita, Osaka, 565-0871, Japan., Yui Y; Sarcoma Treatment Laboratory, Research Institute, Nozaki Tokushukai Hospital, Tanigawa 2-10-50, Daito, Osaka, 574-0074, Japan., Takenaka S; Department of Musculoskeletal Oncology Service, Osaka International Cancer Institute, 3-1-69 Otemae, Chuo-Ku, Osaka, 541-8567, Japan.; Department of Orthopaedic Surgery, Osaka University Graduate School of Medicine, 2-2 Yamadaoka, Suita, Osaka, 565-0871, Japan. |
| Source: | Scientific reports [Sci Rep] 2025 Dec 21; Vol. 16 (1), pp. 2369. Date of Electronic Publication: 2025 Dec 21. |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101563288 Publication Model: Electronic Cited Medium: Internet ISSN: 2045-2322 (Electronic) Linking ISSN: 20452322 NLM ISO Abbreviation: Sci Rep Subsets: MEDLINE; In Process |
| Database: | MEDLINE Ultimate |
| FullText | Text: Availability: 0 |
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| Header | DbId: mdl DbLabel: MEDLINE Ultimate An: 41422105 AccessLevel: 2 PubType: Academic Journal PubTypeId: academicJournal PreciseRelevancyScore: 0 |
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| Items | – Name: Title Label: Title Group: Ti Data: Development of synovial sarcoma organoids exhibiting ferroptosis resistance despite low malic enzyme 1 expression. – Name: Author Label: Authors Group: Au Data: <searchLink fieldCode="AU" term="%22Wakamatsu+T%22">Wakamatsu T</searchLink>; Department of Musculoskeletal Oncology Service, Osaka International Cancer Institute, 3-1-69 Otemae, Chuo-Ku, Osaka, 541-8567, Japan. evolutionhhh49@yahoo.co.jp.; Department of Orthopaedic Surgery, Osaka University Graduate School of Medicine, 2-2 Yamadaoka, Suita, Osaka, 565-0871, Japan. evolutionhhh49@yahoo.co.jp.<br /><searchLink fieldCode="AU" term="%22Yamada+Y%22">Yamada Y</searchLink>; Department of Musculoskeletal Oncology Service, Osaka International Cancer Institute, 3-1-69 Otemae, Chuo-Ku, Osaka, 541-8567, Japan.; Department of Orthopaedic Surgery, Osaka University Graduate School of Medicine, 2-2 Yamadaoka, Suita, Osaka, 565-0871, Japan.<br /><searchLink fieldCode="AU" term="%22Yoshida+K%22">Yoshida K</searchLink>; Next-Generation Precision Medicine Research Center, Osaka International Cancer Institute, 3-1-69 Otemae, Chuo-Ku, Osaka, 541-8567, Japan.<br /><searchLink fieldCode="AU" term="%22Matsuoka+Y%22">Matsuoka Y</searchLink>; Next-Generation Precision Medicine Research Center, Osaka International Cancer Institute, 3-1-69 Otemae, Chuo-Ku, Osaka, 541-8567, Japan.<br /><searchLink fieldCode="AU" term="%22Sasagawa+S%22">Sasagawa S</searchLink>; Molecular Biology Laboratory, Research Institute, Nozaki Tokushukai Hospital, Tanigawa 2-10-50, Daito, Osaka, 574-0074, Japan.<br /><searchLink fieldCode="AU" term="%22Nagamine+N%22">Nagamine N</searchLink>; Department of Musculoskeletal Oncology Service, Osaka International Cancer Institute, 3-1-69 Otemae, Chuo-Ku, Osaka, 541-8567, Japan.<br /><searchLink fieldCode="AU" term="%22Shizuma+K%22">Shizuma K</searchLink>; Department of Cancer Immunotherapy, Research Center, Osaka International Cancer Institute, 3-1-69 Otemae, Chuo-Ku, Osaka, 541-8567, Japan.<br /><searchLink fieldCode="AU" term="%22Suzuki+R%22">Suzuki R</searchLink>; Department of Musculoskeletal Oncology Service, Osaka International Cancer Institute, 3-1-69 Otemae, Chuo-Ku, Osaka, 541-8567, Japan.; Department of Orthopaedic Surgery, Osaka University Graduate School of Medicine, 2-2 Yamadaoka, Suita, Osaka, 565-0871, Japan.<br /><searchLink fieldCode="AU" term="%22Tamiya+H%22">Tamiya H</searchLink>; Department of Musculoskeletal Oncology Service, Osaka International Cancer Institute, 3-1-69 Otemae, Chuo-Ku, Osaka, 541-8567, Japan.; Department of Orthopaedic Surgery, Osaka University Graduate School of Medicine, 2-2 Yamadaoka, Suita, Osaka, 565-0871, Japan.<br /><searchLink fieldCode="AU" term="%22Imura+Y%22">Imura Y</searchLink>; Department of Orthopaedic Surgery, Osaka University Graduate School of Medicine, 2-2 Yamadaoka, Suita, Osaka, 565-0871, Japan.<br /><searchLink fieldCode="AU" term="%22Nakai+S%22">Nakai S</searchLink>; Department of Orthopaedic Surgery, Osaka University Graduate School of Medicine, 2-2 Yamadaoka, Suita, Osaka, 565-0871, Japan.<br /><searchLink fieldCode="AU" term="%22Okada+S%22">Okada S</searchLink>; Department of Orthopaedic Surgery, Osaka University Graduate School of Medicine, 2-2 Yamadaoka, Suita, Osaka, 565-0871, Japan.<br /><searchLink fieldCode="AU" term="%22Yagi+T%22">Yagi T</searchLink>; Department of Musculoskeletal Oncology Service, Osaka International Cancer Institute, 3-1-69 Otemae, Chuo-Ku, Osaka, 541-8567, Japan.<br /><searchLink fieldCode="AU" term="%22Yoshida+KI%22">Yoshida KI</searchLink>; Department of Diagnostic Pathology and Cytology, Osaka International Cancer Institute, 3-1-69 Otemae, Chuo-Ku, Osaka, 541-8567, Japan.<br /><searchLink fieldCode="AU" term="%22Kakunaga+S%22">Kakunaga S</searchLink>; Department of Musculoskeletal Oncology Service, Osaka International Cancer Institute, 3-1-69 Otemae, Chuo-Ku, Osaka, 541-8567, Japan.; Department of Orthopaedic Surgery, Osaka University Graduate School of Medicine, 2-2 Yamadaoka, Suita, Osaka, 565-0871, Japan.<br /><searchLink fieldCode="AU" term="%22Yui+Y%22">Yui Y</searchLink>; Sarcoma Treatment Laboratory, Research Institute, Nozaki Tokushukai Hospital, Tanigawa 2-10-50, Daito, Osaka, 574-0074, Japan.<br /><searchLink fieldCode="AU" term="%22Takenaka+S%22">Takenaka S</searchLink>; Department of Musculoskeletal Oncology Service, Osaka International Cancer Institute, 3-1-69 Otemae, Chuo-Ku, Osaka, 541-8567, Japan.; Department of Orthopaedic Surgery, Osaka University Graduate School of Medicine, 2-2 Yamadaoka, Suita, Osaka, 565-0871, Japan. – Name: TitleSource Label: Source Group: Src Data: <searchLink fieldCode="JN" term="%22101563288%22">Scientific reports</searchLink> [Sci Rep] 2025 Dec 21; Vol. 16 (1), pp. 2369. <i>Date of Electronic Publication: </i>2025 Dec 21. – Name: TypePub Label: Publication Type Group: TypPub Data: Journal Article – Name: TitleSource Label: Journal Info Group: Src Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Nature+Publishing+Group%22">Nature Publishing Group </searchLink><i>Country of Publication: </i>England <i>NLM ID: </i>101563288 <i>Publication Model: </i>Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>2045-2322 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2220452322%22">20452322 </searchLink><i>NLM ISO Abbreviation: </i>Sci Rep <i>Subsets: </i>MEDLINE; In Process |
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| RecordInfo | BibRecord: BibEntity: Identifiers: – Type: doi Value: 10.1038/s41598-025-32030-w Languages: – Code: eng Text: English PhysicalDescription: Pagination: StartPage: 2369 Titles: – TitleFull: Development of synovial sarcoma organoids exhibiting ferroptosis resistance despite low malic enzyme 1 expression. Type: main BibRelationships: HasContributorRelationships: – PersonEntity: Name: NameFull: Wakamatsu T – PersonEntity: Name: NameFull: Yamada Y – PersonEntity: Name: NameFull: Yoshida K – PersonEntity: Name: NameFull: Matsuoka Y – PersonEntity: Name: NameFull: Sasagawa S – PersonEntity: Name: NameFull: Nagamine N – PersonEntity: Name: NameFull: Shizuma K – PersonEntity: Name: NameFull: Suzuki R – PersonEntity: Name: NameFull: Tamiya H – PersonEntity: Name: NameFull: Imura Y – PersonEntity: Name: NameFull: Nakai S – PersonEntity: Name: NameFull: Okada S – PersonEntity: Name: NameFull: Yagi T – PersonEntity: Name: NameFull: Yoshida KI – PersonEntity: Name: NameFull: Kakunaga S – PersonEntity: Name: NameFull: Yui Y – PersonEntity: Name: NameFull: Takenaka S IsPartOfRelationships: – BibEntity: Dates: – D: 21 M: 12 Text: 2025 Dec 21 Type: published Y: 2025 Identifiers: – Type: issn-electronic Value: 2045-2322 Numbering: – Type: volume Value: 16 – Type: issue Value: 1 Titles: – TitleFull: Scientific reports Type: main |
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