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CXCL9 and CXCL10 support the exacerbated humoral response in recovered COVID-19 patients who developed acute respiratory distress syndrome by promoting plasma cell differentiation, whereas CXCL9 also induces CD40L and CXCR3 upregulation on T helper cells.

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Title: CXCL9 and CXCL10 support the exacerbated humoral response in recovered COVID-19 patients who developed acute respiratory distress syndrome by promoting plasma cell differentiation, whereas CXCL9 also induces CD40L and CXCR3 upregulation on T helper cells.
Authors: Quiroga R; Molecular and Translational Immunology Laboratory, Department of Clinical Biochemistry and Immunology, Pharmacy Faculty, University of Concepcion, Concepcion, Chile., Sanhueza S; Molecular and Translational Immunology Laboratory, Department of Clinical Biochemistry and Immunology, Pharmacy Faculty, University of Concepcion, Concepcion, Chile., Sepúlveda C; Molecular and Translational Immunology Laboratory, Department of Clinical Biochemistry and Immunology, Pharmacy Faculty, University of Concepcion, Concepcion, Chile., Antilef B; Molecular and Translational Immunology Laboratory, Department of Clinical Biochemistry and Immunology, Pharmacy Faculty, University of Concepcion, Concepcion, Chile., Muñoz C; Molecular and Translational Immunology Laboratory, Department of Clinical Biochemistry and Immunology, Pharmacy Faculty, University of Concepcion, Concepcion, Chile.; Facultad de Odontología, Universidad San Sebastián, Concepción, Chile., Cabrera C; Molecular and Translational Immunology Laboratory, Department of Clinical Biochemistry and Immunology, Pharmacy Faculty, University of Concepcion, Concepcion, Chile., Fraga M; Molecular and Translational Immunology Laboratory, Department of Clinical Biochemistry and Immunology, Pharmacy Faculty, University of Concepcion, Concepcion, Chile., Llerena F; Molecular and Translational Immunology Laboratory, Department of Clinical Biochemistry and Immunology, Pharmacy Faculty, University of Concepcion, Concepcion, Chile., Lamperti L; Molecular and Translational Immunology Laboratory, Department of Clinical Biochemistry and Immunology, Pharmacy Faculty, University of Concepcion, Concepcion, Chile., Barría MI; Facultad de Medicina, Universidad San Sebastián, Puerto Montt, Chile., Colombo A; Basic and Clinical Oncology Department, Faculty of Medicine, University of Chile, Santiago, Chile.; Pathological Anatomy Service, Clinical Hospital at University of Chile, Santiago, Chile.; Department of Pathological Anatomy, Faculty of Medicine, University of Chile, Santiago, Chile., Labarca G; Molecular and Translational Immunology Laboratory, Department of Clinical Biochemistry and Immunology, Pharmacy Faculty, University of Concepcion, Concepcion, Chile.; Internal Medicine, Complejo Asistencial Dr. Víctor Ríos Ruiz, Los Ángeles, Chile.; Division of Sleep and Circadian Disorders, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, United States., Henríquez-Beltrán M; Translational Research in Respiratory Medicine, Biomedical Research Institute of Lleida (IRBLleida), Hospital Universitari Arnau de Vilanova-Santa Maria, Lleida, Spain.; Escuela de Kinesiología, Facultad de Salud, Universidad Santo Tomás, Los Ángeles, Chile.; Núcleo de Investigación en Ciencias de la Salud, Universidad Adventista de Chile, Chillán, Chile.; Centro de Investigación Biomédica en Red (CIBER) of Respiratory Diseases (CIBERES), Institute of Health Carlos III, Madrid, Spain., Ferrada L; Centro de Microscopía Avanzada Biobío (CMA), University of Concepcion, Concepcion, Chile., Nova-Lamperti E; Molecular and Translational Immunology Laboratory, Department of Clinical Biochemistry and Immunology, Pharmacy Faculty, University of Concepcion, Concepcion, Chile.
Source: Frontiers in immunology [Front Immunol] 2025 Dec 04; Vol. 16, pp. 1684704. Date of Electronic Publication: 2025 Dec 04 (Print Publication: 2025).
Publication Type: Journal Article
Journal Info: Publisher: Frontiers Research Foundation] Country of Publication: Switzerland NLM ID: 101560960 Publication Model: eCollection Cited Medium: Internet ISSN: 1664-3224 (Electronic) Linking ISSN: 16643224 NLM ISO Abbreviation: Front Immunol Subsets: MEDLINE
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  Data: CXCL9 and CXCL10 support the exacerbated humoral response in recovered COVID-19 patients who developed acute respiratory distress syndrome by promoting plasma cell differentiation, whereas CXCL9 also induces CD40L and CXCR3 upregulation on T helper cells.
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  Data: <searchLink fieldCode="AU" term="%22Quiroga+R%22">Quiroga R</searchLink>; Molecular and Translational Immunology Laboratory, Department of Clinical Biochemistry and Immunology, Pharmacy Faculty, University of Concepcion, Concepcion, Chile.<br /><searchLink fieldCode="AU" term="%22Sanhueza+S%22">Sanhueza S</searchLink>; Molecular and Translational Immunology Laboratory, Department of Clinical Biochemistry and Immunology, Pharmacy Faculty, University of Concepcion, Concepcion, Chile.<br /><searchLink fieldCode="AU" term="%22Sepúlveda+C%22">Sepúlveda C</searchLink>; Molecular and Translational Immunology Laboratory, Department of Clinical Biochemistry and Immunology, Pharmacy Faculty, University of Concepcion, Concepcion, Chile.<br /><searchLink fieldCode="AU" term="%22Antilef+B%22">Antilef B</searchLink>; Molecular and Translational Immunology Laboratory, Department of Clinical Biochemistry and Immunology, Pharmacy Faculty, University of Concepcion, Concepcion, Chile.<br /><searchLink fieldCode="AU" term="%22Muñoz+C%22">Muñoz C</searchLink>; Molecular and Translational Immunology Laboratory, Department of Clinical Biochemistry and Immunology, Pharmacy Faculty, University of Concepcion, Concepcion, Chile.; Facultad de Odontología, Universidad San Sebastián, Concepción, Chile.<br /><searchLink fieldCode="AU" term="%22Cabrera+C%22">Cabrera C</searchLink>; Molecular and Translational Immunology Laboratory, Department of Clinical Biochemistry and Immunology, Pharmacy Faculty, University of Concepcion, Concepcion, Chile.<br /><searchLink fieldCode="AU" term="%22Fraga+M%22">Fraga M</searchLink>; Molecular and Translational Immunology Laboratory, Department of Clinical Biochemistry and Immunology, Pharmacy Faculty, University of Concepcion, Concepcion, Chile.<br /><searchLink fieldCode="AU" term="%22Llerena+F%22">Llerena F</searchLink>; Molecular and Translational Immunology Laboratory, Department of Clinical Biochemistry and Immunology, Pharmacy Faculty, University of Concepcion, Concepcion, Chile.<br /><searchLink fieldCode="AU" term="%22Lamperti+L%22">Lamperti L</searchLink>; Molecular and Translational Immunology Laboratory, Department of Clinical Biochemistry and Immunology, Pharmacy Faculty, University of Concepcion, Concepcion, Chile.<br /><searchLink fieldCode="AU" term="%22Barría+MI%22">Barría MI</searchLink>; Facultad de Medicina, Universidad San Sebastián, Puerto Montt, Chile.<br /><searchLink fieldCode="AU" term="%22Colombo+A%22">Colombo A</searchLink>; Basic and Clinical Oncology Department, Faculty of Medicine, University of Chile, Santiago, Chile.; Pathological Anatomy Service, Clinical Hospital at University of Chile, Santiago, Chile.; Department of Pathological Anatomy, Faculty of Medicine, University of Chile, Santiago, Chile.<br /><searchLink fieldCode="AU" term="%22Labarca+G%22">Labarca G</searchLink>; Molecular and Translational Immunology Laboratory, Department of Clinical Biochemistry and Immunology, Pharmacy Faculty, University of Concepcion, Concepcion, Chile.; Internal Medicine, Complejo Asistencial Dr. Víctor Ríos Ruiz, Los Ángeles, Chile.; Division of Sleep and Circadian Disorders, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, United States.<br /><searchLink fieldCode="AU" term="%22Henríquez-Beltrán+M%22">Henríquez-Beltrán M</searchLink>; Translational Research in Respiratory Medicine, Biomedical Research Institute of Lleida (IRBLleida), Hospital Universitari Arnau de Vilanova-Santa Maria, Lleida, Spain.; Escuela de Kinesiología, Facultad de Salud, Universidad Santo Tomás, Los Ángeles, Chile.; Núcleo de Investigación en Ciencias de la Salud, Universidad Adventista de Chile, Chillán, Chile.; Centro de Investigación Biomédica en Red (CIBER) of Respiratory Diseases (CIBERES), Institute of Health Carlos III, Madrid, Spain.<br /><searchLink fieldCode="AU" term="%22Ferrada+L%22">Ferrada L</searchLink>; Centro de Microscopía Avanzada Biobío (CMA), University of Concepcion, Concepcion, Chile.<br /><searchLink fieldCode="AU" term="%22Nova-Lamperti+E%22">Nova-Lamperti E</searchLink>; Molecular and Translational Immunology Laboratory, Department of Clinical Biochemistry and Immunology, Pharmacy Faculty, University of Concepcion, Concepcion, Chile.
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  Data: <searchLink fieldCode="JN" term="%22101560960%22">Frontiers in immunology</searchLink> [Front Immunol] 2025 Dec 04; Vol. 16, pp. 1684704. <i>Date of Electronic Publication: </i>2025 Dec 04 (<i>Print Publication: </i>2025).
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