Integrated genomic analysis and CRISPRi implicates EGFR in Alzheimer's disease risk.
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| Title: | Integrated genomic analysis and CRISPRi implicates EGFR in Alzheimer's disease risk. |
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| Authors: | Leung YY; Penn Neurodegeneration Genomics Center, Department of Pathology and Laboratory Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA USA., Kuksa PP; Penn Neurodegeneration Genomics Center, Department of Pathology and Laboratory Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA USA., Carter L; Penn Neurodegeneration Genomics Center, Department of Pathology and Laboratory Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA USA., Cifello J; Penn Neurodegeneration Genomics Center, Department of Pathology and Laboratory Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA USA., Greenfest-Allen E; Penn Neurodegeneration Genomics Center, Department of Pathology and Laboratory Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA USA., Valladares O; Penn Neurodegeneration Genomics Center, Department of Pathology and Laboratory Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA USA., Boateng L; Penn Neurodegeneration Genomics Center, Department of Pathology and Laboratory Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA USA., Laub S; Penn Neurodegeneration Genomics Center, Department of Pathology and Laboratory Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA USA., Tulina N; Penn Neurodegeneration Genomics Center, Department of Pathology and Laboratory Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA USA., Moura S; John P. Hussman Institute for Human Genomics, University of Miami Miller School of Medicine, Miami, FL USA., Ramirez A; John P. Hussman Institute for Human Genomics, University of Miami Miller School of Medicine, Miami, FL USA., Celis K; John P. Hussman Institute for Human Genomics, University of Miami Miller School of Medicine, Miami, FL USA., Jin F; Department of Genetics and Genome Sciences, School of Medicine, Case Western Reserve University, Cleveland, OH USA., Feng R; Center for Statistical Genetics, The Gertrude H. Sergievsky Center, Columbia University, New York, NY USA.; Department of Neurology, Columbia University, New York, NY USA., Wang G; Center for Statistical Genetics, The Gertrude H. Sergievsky Center, Columbia University, New York, NY USA.; Department of Neurology, Columbia University, New York, NY USA., De Jager P; Center for Statistical Genetics, The Gertrude H. Sergievsky Center, Columbia University, New York, NY USA.; Department of Neurology, Columbia University, New York, NY USA., Vance JM; John P. Hussman Institute for Human Genomics, University of Miami Miller School of Medicine, Miami, FL USA., Wang L; John P. Hussman Institute for Human Genomics, University of Miami Miller School of Medicine, Miami, FL USA., Grant SFA; Penn Neurodegeneration Genomics Center, Department of Pathology and Laboratory Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA USA.; Center for Spatial and Functional Genomics, The Children's Hospital of Philadelphia, Philadelphia, PA USA.; Divisions of Human Genetics and Endocrinology & Diabetes, The Children's Hospital of Philadelphia, Philadelphia, PA USA.; Department of Genetics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA USA.; Department of Pediatrics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA USA., Schellenberg GD; Penn Neurodegeneration Genomics Center, Department of Pathology and Laboratory Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA USA., Chesi A; Penn Neurodegeneration Genomics Center, Department of Pathology and Laboratory Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA USA.; Center for Spatial and Functional Genomics, The Children's Hospital of Philadelphia, Philadelphia, PA USA., Wang LS; Penn Neurodegeneration Genomics Center, Department of Pathology and Laboratory Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA USA. |
| Source: | NPJ dementia [NPJ Dement] 2025; Vol. 1 (1), pp. 42. Date of Electronic Publication: 2025 Dec 16. |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: Nature Publishing Group UK Country of Publication: England NLM ID: 9918993995206676 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 3005-1940 (Electronic) Linking ISSN: 30051940 NLM ISO Abbreviation: NPJ Dement Subsets: PubMed not MEDLINE |
| Database: | MEDLINE Ultimate |
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