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Redox Stoichiometry at the Single-Residue Level Using Mass Spectrometry Reveals Dynamic Methionine Sulfoxide Speciation in Actin and Calmodulin during Brain Aging.

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Title: Redox Stoichiometry at the Single-Residue Level Using Mass Spectrometry Reveals Dynamic Methionine Sulfoxide Speciation in Actin and Calmodulin during Brain Aging.
Authors: Hwang J; Center for Proteomics and Bioinformatics, Department of Nutrition, School of Medicine, Case Western Reserve University, Cleveland, Ohio 44106, United States., Clore MF; Center for Proteomics and Bioinformatics, Department of Nutrition, School of Medicine, Case Western Reserve University, Cleveland, Ohio 44106, United States., Blasco Tavares Pereira Lopes F; Center for Proteomics and Bioinformatics, Department of Nutrition, School of Medicine, Case Western Reserve University, Cleveland, Ohio 44106, United States., Ayati M; Department of Computer Science, University of Texas Rio Grande Valley, Edinburg, Texas 78539, United States., Schlatzer D; Center for Proteomics and Bioinformatics, Department of Nutrition, School of Medicine, Case Western Reserve University, Cleveland, Ohio 44106, United States., Qi X; Center for Mitochondrial Research and Therapeutics, Case Western Reserve University, Cleveland, Ohio 44106, United States.; Department of Physiology & Biophysics, School of Medicine, Case Western Reserve University, Cleveland, Ohio 44106, United States., Wang R; Center for Mitochondrial Research and Therapeutics, Case Western Reserve University, Cleveland, Ohio 44106, United States.; Department of Physiology & Biophysics, School of Medicine, Case Western Reserve University, Cleveland, Ohio 44106, United States., Koyuturk M; Department of Computer and Data Sciences, Case School of Engineering, Case Western Reserve University, Cleveland, Ohio 44106, United States., Chance MR; Center for Proteomics and Bioinformatics, Department of Nutrition, School of Medicine, Case Western Reserve University, Cleveland, Ohio 44106, United States.
Source: Journal of proteome research [J Proteome Res] 2026 Feb 06; Vol. 25 (2), pp. 765-774. Date of Electronic Publication: 2025 Dec 22.
Publication Type: Journal Article
Journal Info: Publisher: American Chemical Society Country of Publication: United States NLM ID: 101128775 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1535-3907 (Electronic) Linking ISSN: 15353893 NLM ISO Abbreviation: J Proteome Res Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Redox Stoichiometry at the Single-Residue Level Using Mass Spectrometry Reveals Dynamic Methionine Sulfoxide Speciation in Actin and Calmodulin during Brain Aging.
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  Data: <searchLink fieldCode="AU" term="%22Hwang+J%22">Hwang J</searchLink>; Center for Proteomics and Bioinformatics, Department of Nutrition, School of Medicine, Case Western Reserve University, Cleveland, Ohio 44106, United States.<br /><searchLink fieldCode="AU" term="%22Clore+MF%22">Clore MF</searchLink>; Center for Proteomics and Bioinformatics, Department of Nutrition, School of Medicine, Case Western Reserve University, Cleveland, Ohio 44106, United States.<br /><searchLink fieldCode="AU" term="%22Blasco+Tavares+Pereira+Lopes+F%22">Blasco Tavares Pereira Lopes F</searchLink>; Center for Proteomics and Bioinformatics, Department of Nutrition, School of Medicine, Case Western Reserve University, Cleveland, Ohio 44106, United States.<br /><searchLink fieldCode="AU" term="%22Ayati+M%22">Ayati M</searchLink>; Department of Computer Science, University of Texas Rio Grande Valley, Edinburg, Texas 78539, United States.<br /><searchLink fieldCode="AU" term="%22Schlatzer+D%22">Schlatzer D</searchLink>; Center for Proteomics and Bioinformatics, Department of Nutrition, School of Medicine, Case Western Reserve University, Cleveland, Ohio 44106, United States.<br /><searchLink fieldCode="AU" term="%22Qi+X%22">Qi X</searchLink>; Center for Mitochondrial Research and Therapeutics, Case Western Reserve University, Cleveland, Ohio 44106, United States.; Department of Physiology & Biophysics, School of Medicine, Case Western Reserve University, Cleveland, Ohio 44106, United States.<br /><searchLink fieldCode="AU" term="%22Wang+R%22">Wang R</searchLink>; Center for Mitochondrial Research and Therapeutics, Case Western Reserve University, Cleveland, Ohio 44106, United States.; Department of Physiology & Biophysics, School of Medicine, Case Western Reserve University, Cleveland, Ohio 44106, United States.<br /><searchLink fieldCode="AU" term="%22Koyuturk+M%22">Koyuturk M</searchLink>; Department of Computer and Data Sciences, Case School of Engineering, Case Western Reserve University, Cleveland, Ohio 44106, United States.<br /><searchLink fieldCode="AU" term="%22Chance+MR%22">Chance MR</searchLink>; Center for Proteomics and Bioinformatics, Department of Nutrition, School of Medicine, Case Western Reserve University, Cleveland, Ohio 44106, United States.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22American+Chemical+Society%22">American Chemical Society </searchLink><i>Country of Publication: </i>United States <i>NLM ID: </i>101128775 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1535-3907 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2215353893%22">15353893 </searchLink><i>NLM ISO Abbreviation: </i>J Proteome Res <i>Subsets: </i>MEDLINE
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        Value: 10.1021/acs.jproteome.5c00715
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        Text: English
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      – TitleFull: Redox Stoichiometry at the Single-Residue Level Using Mass Spectrometry Reveals Dynamic Methionine Sulfoxide Speciation in Actin and Calmodulin during Brain Aging.
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              Text: 2026 Feb 06
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