Stable remission of depression after antidepressant treatment: prevalence and related sociodemographic and clinical characteristics in a longitudinal, real-world cohort.

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Title: Stable remission of depression after antidepressant treatment: prevalence and related sociodemographic and clinical characteristics in a longitudinal, real-world cohort.
Authors: Bot M; Department of Psychiatry, Amsterdam University Medical Center, Vrije Universiteit Amsterdam, Amsterdam Public Health, Mental Health Program, De Boelelaan 1117, 1081 HV, Amsterdam, the Netherlands. Electronic address: m.bot1@amsterdamumc.nl., Ligthart SA; Department of Primary and Community Care, Radboud university medical center Research Institute for Medical Innovation, Geert Grooteplein Zuid 10, 6525 GA, Nijmegen, the Netherlands., Burger H; Department of Primary and Long-term Care, University Medical Center Groningen, University of Groningen, Hanzeplein 1, 9713 GZ, Groningen, the Netherlands., Grootendorst-van Mil NH; Department of Psychiatry, Erasmus MC University Medical Center, Dr. Molewaterplein 40, 3015 GD, Rotterdam, the Netherlands., Arnold IA; Department of Public Health and Primary Care, Leiden University Medical Centre, Albinusdreef 2, 2333 ZG, Leiden, the Netherlands., van Belkum SM; Department of Psychiatry, Research School of Behavioral and Cognitive Neurosciences (BCN), Interdisciplinary Center Psychopathology of Emotion Regulation (ICPE), University Medical Center Groningen, University of Groningen, Hanzeplein 1, 9713 GZ, Groningen, the Netherlands., Bet PM; Department of Clinical Pharmacology and Pharmacy, Amsterdam University Medical Center, Vrije Universiteit Amsterdam, De Boelelaan 1117, 1081 HV, Amsterdam, the Netherlands; Personalized Medicine Programme, Amsterdam Public Health Research Institute, Amsterdam, the Netherlands; Amsterdam Neuroscience, Amsterdam, the Netherlands., Birkenhager TK; Department of Psychiatry, Erasmus MC University Medical Center, Dr. Molewaterplein 40, 3015 GD, Rotterdam, the Netherlands., Göttgens W; Department of Primary and Community Care, Radboud university medical center Research Institute for Medical Innovation, Geert Grooteplein Zuid 10, 6525 GA, Nijmegen, the Netherlands., Hugtenburg JG; Department of Clinical Pharmacology and Pharmacy, Amsterdam University Medical Center, Vrije Universiteit Amsterdam, De Boelelaan 1117, 1081 HV, Amsterdam, the Netherlands., Maarsingh OR; Department of General Practice, Amsterdam University Medical Center, Amsterdam Public Health, De Boelelaan 1117, 1081 HV, Amsterdam, the Netherlands., Ruhé HG; Department of Psychiatry, Radboudumc, Radboud University, Geert Grooteplein Zuid 10, 6525 GA, Nijmegen, the Netherlands., Spijker J; Pro Persona Mental Health Care, Pro Persona Research, Depression Expertise Center, Nijmeegsebaan 61, 6525 DX, Nijmegen, the Netherlands., Vinkers CH; Department of Psychiatry, Amsterdam University Medical Center, Vrije Universiteit Amsterdam, Amsterdam Public Health, Mental Health Program, De Boelelaan 1117, 1081 HV, Amsterdam, the Netherlands; Amsterdam Neuroscience, Amsterdam, the Netherlands., Penninx BWJH; Department of Psychiatry, Amsterdam University Medical Center, Vrije Universiteit Amsterdam, Amsterdam Public Health, Mental Health Program, De Boelelaan 1117, 1081 HV, Amsterdam, the Netherlands; Amsterdam Neuroscience, Amsterdam, the Netherlands.
Source: Journal of affective disorders [J Affect Disord] 2026 Apr 01; Vol. 398, pp. 121011. Date of Electronic Publication: 2025 Dec 20.
Publication Type: Journal Article; Observational Study
Journal Info: Publisher: Elsevier/North-Holland Biomedical Press Country of Publication: Netherlands NLM ID: 7906073 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1573-2517 (Electronic) Linking ISSN: 01650327 NLM ISO Abbreviation: J Affect Disord Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: <searchLink fieldCode="AU" term="%22Bot+M%22">Bot M</searchLink>; Department of Psychiatry, Amsterdam University Medical Center, Vrije Universiteit Amsterdam, Amsterdam Public Health, Mental Health Program, De Boelelaan 1117, 1081 HV, Amsterdam, the Netherlands. Electronic address: m.bot1@amsterdamumc.nl.<br /><searchLink fieldCode="AU" term="%22Ligthart+SA%22">Ligthart SA</searchLink>; Department of Primary and Community Care, Radboud university medical center Research Institute for Medical Innovation, Geert Grooteplein Zuid 10, 6525 GA, Nijmegen, the Netherlands.<br /><searchLink fieldCode="AU" term="%22Burger+H%22">Burger H</searchLink>; Department of Primary and Long-term Care, University Medical Center Groningen, University of Groningen, Hanzeplein 1, 9713 GZ, Groningen, the Netherlands.<br /><searchLink fieldCode="AU" term="%22Grootendorst-van+Mil+NH%22">Grootendorst-van Mil NH</searchLink>; Department of Psychiatry, Erasmus MC University Medical Center, Dr. Molewaterplein 40, 3015 GD, Rotterdam, the Netherlands.<br /><searchLink fieldCode="AU" term="%22Arnold+IA%22">Arnold IA</searchLink>; Department of Public Health and Primary Care, Leiden University Medical Centre, Albinusdreef 2, 2333 ZG, Leiden, the Netherlands.<br /><searchLink fieldCode="AU" term="%22van+Belkum+SM%22">van Belkum SM</searchLink>; Department of Psychiatry, Research School of Behavioral and Cognitive Neurosciences (BCN), Interdisciplinary Center Psychopathology of Emotion Regulation (ICPE), University Medical Center Groningen, University of Groningen, Hanzeplein 1, 9713 GZ, Groningen, the Netherlands.<br /><searchLink fieldCode="AU" term="%22Bet+PM%22">Bet PM</searchLink>; Department of Clinical Pharmacology and Pharmacy, Amsterdam University Medical Center, Vrije Universiteit Amsterdam, De Boelelaan 1117, 1081 HV, Amsterdam, the Netherlands; Personalized Medicine Programme, Amsterdam Public Health Research Institute, Amsterdam, the Netherlands; Amsterdam Neuroscience, Amsterdam, the Netherlands.<br /><searchLink fieldCode="AU" term="%22Birkenhager+TK%22">Birkenhager TK</searchLink>; Department of Psychiatry, Erasmus MC University Medical Center, Dr. Molewaterplein 40, 3015 GD, Rotterdam, the Netherlands.<br /><searchLink fieldCode="AU" term="%22Göttgens+W%22">Göttgens W</searchLink>; Department of Primary and Community Care, Radboud university medical center Research Institute for Medical Innovation, Geert Grooteplein Zuid 10, 6525 GA, Nijmegen, the Netherlands.<br /><searchLink fieldCode="AU" term="%22Hugtenburg+JG%22">Hugtenburg JG</searchLink>; Department of Clinical Pharmacology and Pharmacy, Amsterdam University Medical Center, Vrije Universiteit Amsterdam, De Boelelaan 1117, 1081 HV, Amsterdam, the Netherlands.<br /><searchLink fieldCode="AU" term="%22Maarsingh+OR%22">Maarsingh OR</searchLink>; Department of General Practice, Amsterdam University Medical Center, Amsterdam Public Health, De Boelelaan 1117, 1081 HV, Amsterdam, the Netherlands.<br /><searchLink fieldCode="AU" term="%22Ruhé+HG%22">Ruhé HG</searchLink>; Department of Psychiatry, Radboudumc, Radboud University, Geert Grooteplein Zuid 10, 6525 GA, Nijmegen, the Netherlands.<br /><searchLink fieldCode="AU" term="%22Spijker+J%22">Spijker J</searchLink>; Pro Persona Mental Health Care, Pro Persona Research, Depression Expertise Center, Nijmeegsebaan 61, 6525 DX, Nijmegen, the Netherlands.<br /><searchLink fieldCode="AU" term="%22Vinkers+CH%22">Vinkers CH</searchLink>; Department of Psychiatry, Amsterdam University Medical Center, Vrije Universiteit Amsterdam, Amsterdam Public Health, Mental Health Program, De Boelelaan 1117, 1081 HV, Amsterdam, the Netherlands; Amsterdam Neuroscience, Amsterdam, the Netherlands.<br /><searchLink fieldCode="AU" term="%22Penninx+BWJH%22">Penninx BWJH</searchLink>; Department of Psychiatry, Amsterdam University Medical Center, Vrije Universiteit Amsterdam, Amsterdam Public Health, Mental Health Program, De Boelelaan 1117, 1081 HV, Amsterdam, the Netherlands; Amsterdam Neuroscience, Amsterdam, the Netherlands.
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        Value: 10.1016/j.jad.2025.121011
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