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Efficacy of cefiderocol in murine models of ventilator-associated pneumonia caused by carbapenem-resistant non-fermenting Gram-negative bacilli, with pharmacokinetic evaluation.

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Title: Efficacy of cefiderocol in murine models of ventilator-associated pneumonia caused by carbapenem-resistant non-fermenting Gram-negative bacilli, with pharmacokinetic evaluation.
Authors: Ota K; Department of Laboratory Medicine, Nagasaki University Graduate School of Biomedical Sciences, Nagasaki, Japan.; Department of Laboratory Medicine, Nagasaki University Hospital, Nagasaki, Japan., Kaku N; Department of Laboratory Medicine, Nagasaki University Graduate School of Biomedical Sciences, Nagasaki, Japan.; Department of Laboratory Medicine, Nagasaki University Hospital, Nagasaki, Japan., Mitsumoto-Kaseida F; Department of Laboratory Medicine, Nagasaki University Graduate School of Biomedical Sciences, Nagasaki, Japan.; Department of Laboratory Medicine, Nagasaki University Hospital, Nagasaki, Japan., Uno N; Department of Medical Virology, Nagasaki University Graduate School of Biomedical Sciences, Nagasaki, Japan., Kosai K; Department of Laboratory Medicine, Nagasaki University Graduate School of Biomedical Sciences, Nagasaki, Japan.; Department of Laboratory Medicine, Nagasaki University Hospital, Nagasaki, Japan., Takazono T; Department of Infectious Diseases, Nagasaki University Graduate School of Biomedical Sciences, Nagasaki, Japan.; Department of Respiratory Medicine, Nagasaki University Graduate School of Biomedical Sciences, Nagasaki, Japan., Hasegawa H; Department of Laboratory Medicine, Nagasaki University Graduate School of Biomedical Sciences, Nagasaki, Japan.; Department of Laboratory Medicine, Nagasaki University Hospital, Nagasaki, Japan., Sakamoto K; Department of Microbiology and Immunology, Graduate School of Medicine, Yamaguchi University, Yamaguchi, Japan., Morinaga Y; Department of Microbiology, Faculty of Medicine, Academic Assembly, University of Toyama, Toyama, Japan., Izumikawa K; Department of Infectious Diseases, Nagasaki University Graduate School of Biomedical Sciences, Nagasaki, Japan., Mukae H; Department of Respiratory Medicine, Nagasaki University Graduate School of Biomedical Sciences, Nagasaki, Japan., Mikamo H; Department of Clinical Infectious Diseases, Aichi Medical University Graduate School of Medicine, Aichi, Japan., Yanagihara K; Department of Laboratory Medicine, Nagasaki University Graduate School of Biomedical Sciences, Nagasaki, Japan.; Department of Laboratory Medicine, Nagasaki University Hospital, Nagasaki, Japan.
Source: Microbiology spectrum [Microbiol Spectr] 2026 Feb 03; Vol. 14 (2), pp. e0256825. Date of Electronic Publication: 2025 Dec 23.
Publication Type: Journal Article
Journal Info: Publisher: ASM Press Country of Publication: United States NLM ID: 101634614 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2165-0497 (Electronic) Linking ISSN: 21650497 NLM ISO Abbreviation: Microbiol Spectr Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Efficacy of cefiderocol in murine models of ventilator-associated pneumonia caused by carbapenem-resistant non-fermenting Gram-negative bacilli, with pharmacokinetic evaluation.
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  Data: <searchLink fieldCode="AU" term="%22Ota+K%22">Ota K</searchLink>; Department of Laboratory Medicine, Nagasaki University Graduate School of Biomedical Sciences, Nagasaki, Japan.; Department of Laboratory Medicine, Nagasaki University Hospital, Nagasaki, Japan.<br /><searchLink fieldCode="AU" term="%22Kaku+N%22">Kaku N</searchLink>; Department of Laboratory Medicine, Nagasaki University Graduate School of Biomedical Sciences, Nagasaki, Japan.; Department of Laboratory Medicine, Nagasaki University Hospital, Nagasaki, Japan.<br /><searchLink fieldCode="AU" term="%22Mitsumoto-Kaseida+F%22">Mitsumoto-Kaseida F</searchLink>; Department of Laboratory Medicine, Nagasaki University Graduate School of Biomedical Sciences, Nagasaki, Japan.; Department of Laboratory Medicine, Nagasaki University Hospital, Nagasaki, Japan.<br /><searchLink fieldCode="AU" term="%22Uno+N%22">Uno N</searchLink>; Department of Medical Virology, Nagasaki University Graduate School of Biomedical Sciences, Nagasaki, Japan.<br /><searchLink fieldCode="AU" term="%22Kosai+K%22">Kosai K</searchLink>; Department of Laboratory Medicine, Nagasaki University Graduate School of Biomedical Sciences, Nagasaki, Japan.; Department of Laboratory Medicine, Nagasaki University Hospital, Nagasaki, Japan.<br /><searchLink fieldCode="AU" term="%22Takazono+T%22">Takazono T</searchLink>; Department of Infectious Diseases, Nagasaki University Graduate School of Biomedical Sciences, Nagasaki, Japan.; Department of Respiratory Medicine, Nagasaki University Graduate School of Biomedical Sciences, Nagasaki, Japan.<br /><searchLink fieldCode="AU" term="%22Hasegawa+H%22">Hasegawa H</searchLink>; Department of Laboratory Medicine, Nagasaki University Graduate School of Biomedical Sciences, Nagasaki, Japan.; Department of Laboratory Medicine, Nagasaki University Hospital, Nagasaki, Japan.<br /><searchLink fieldCode="AU" term="%22Sakamoto+K%22">Sakamoto K</searchLink>; Department of Microbiology and Immunology, Graduate School of Medicine, Yamaguchi University, Yamaguchi, Japan.<br /><searchLink fieldCode="AU" term="%22Morinaga+Y%22">Morinaga Y</searchLink>; Department of Microbiology, Faculty of Medicine, Academic Assembly, University of Toyama, Toyama, Japan.<br /><searchLink fieldCode="AU" term="%22Izumikawa+K%22">Izumikawa K</searchLink>; Department of Infectious Diseases, Nagasaki University Graduate School of Biomedical Sciences, Nagasaki, Japan.<br /><searchLink fieldCode="AU" term="%22Mukae+H%22">Mukae H</searchLink>; Department of Respiratory Medicine, Nagasaki University Graduate School of Biomedical Sciences, Nagasaki, Japan.<br /><searchLink fieldCode="AU" term="%22Mikamo+H%22">Mikamo H</searchLink>; Department of Clinical Infectious Diseases, Aichi Medical University Graduate School of Medicine, Aichi, Japan.<br /><searchLink fieldCode="AU" term="%22Yanagihara+K%22">Yanagihara K</searchLink>; Department of Laboratory Medicine, Nagasaki University Graduate School of Biomedical Sciences, Nagasaki, Japan.; Department of Laboratory Medicine, Nagasaki University Hospital, Nagasaki, Japan.
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  Data: <searchLink fieldCode="JN" term="%22101634614%22">Microbiology spectrum</searchLink> [Microbiol Spectr] 2026 Feb 03; Vol. 14 (2), pp. e0256825. <i>Date of Electronic Publication: </i>2025 Dec 23.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22ASM+Press%22">ASM Press </searchLink><i>Country of Publication: </i>United States <i>NLM ID: </i>101634614 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>2165-0497 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2221650497%22">21650497 </searchLink><i>NLM ISO Abbreviation: </i>Microbiol Spectr <i>Subsets: </i>MEDLINE
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              Text: 2026 Feb 03
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