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Development and validation of a rapid LC-MS/MS method for methylphenidate, atomoxetine, and their metabolites with application to pediatric pharmacokinetics.

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Title: Development and validation of a rapid LC-MS/MS method for methylphenidate, atomoxetine, and their metabolites with application to pediatric pharmacokinetics.
Authors: Eryavuz Onmaz D; Department of Biochemistry, Bandirma Onyedi Eylul University Faculty of Medicine, Bandirma, Turkey. Electronic address: donmaz@bandirma.edu.tr., Kuz M; Department of Child and Adolescent Psychiatry, Diamind Mental Academy, Konya, Turkey., Cetin FH; Department of Child and Adolescent Psychiatry, Diamind Mental Academy, Konya, Turkey., Ucar HN; Department of Child and Adolescent Psychiatry, Diamind Mental Academy, Konya, Turkey., Turkoglu S; Department of Child and Adolescent Psychiatry, Selcuk University Faculty of Medicine, Konya, Turkey., Coban R; Department of Biochemistry, Selcuk University Faculty of Medicine, Konya, Turkey., Unlu A; Department of Biochemistry, Selcuk University Faculty of Medicine, Konya, Turkey.
Source: Journal of pharmaceutical and biomedical analysis [J Pharm Biomed Anal] 2026 Apr 15; Vol. 271, pp. 117321. Date of Electronic Publication: 2025 Dec 19.
Publication Type: Journal Article; Validation Study
Journal Info: Publisher: Elsevier Science Country of Publication: England NLM ID: 8309336 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1873-264X (Electronic) Linking ISSN: 07317085 NLM ISO Abbreviation: J Pharm Biomed Anal Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Development and validation of a rapid LC-MS/MS method for methylphenidate, atomoxetine, and their metabolites with application to pediatric pharmacokinetics.
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  Data: <searchLink fieldCode="AU" term="%22Eryavuz+Onmaz+D%22">Eryavuz Onmaz D</searchLink>; Department of Biochemistry, Bandirma Onyedi Eylul University Faculty of Medicine, Bandirma, Turkey. Electronic address: donmaz@bandirma.edu.tr.<br /><searchLink fieldCode="AU" term="%22Kuz+M%22">Kuz M</searchLink>; Department of Child and Adolescent Psychiatry, Diamind Mental Academy, Konya, Turkey.<br /><searchLink fieldCode="AU" term="%22Cetin+FH%22">Cetin FH</searchLink>; Department of Child and Adolescent Psychiatry, Diamind Mental Academy, Konya, Turkey.<br /><searchLink fieldCode="AU" term="%22Ucar+HN%22">Ucar HN</searchLink>; Department of Child and Adolescent Psychiatry, Diamind Mental Academy, Konya, Turkey.<br /><searchLink fieldCode="AU" term="%22Turkoglu+S%22">Turkoglu S</searchLink>; Department of Child and Adolescent Psychiatry, Selcuk University Faculty of Medicine, Konya, Turkey.<br /><searchLink fieldCode="AU" term="%22Coban+R%22">Coban R</searchLink>; Department of Biochemistry, Selcuk University Faculty of Medicine, Konya, Turkey.<br /><searchLink fieldCode="AU" term="%22Unlu+A%22">Unlu A</searchLink>; Department of Biochemistry, Selcuk University Faculty of Medicine, Konya, Turkey.
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  Data: <searchLink fieldCode="JN" term="%228309336%22">Journal of pharmaceutical and biomedical analysis</searchLink> [J Pharm Biomed Anal] 2026 Apr 15; Vol. 271, pp. 117321. <i>Date of Electronic Publication: </i>2025 Dec 19.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Elsevier+Science%22">Elsevier Science </searchLink><i>Country of Publication: </i>England <i>NLM ID: </i>8309336 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1873-264X (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2207317085%22">07317085 </searchLink><i>NLM ISO Abbreviation: </i>J Pharm Biomed Anal <i>Subsets: </i>MEDLINE
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        Value: 10.1016/j.jpba.2025.117321
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              Text: 2026 Apr 15
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