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Pharmacodynamics of vicadrostat for aldosterone synthase inhibition in patients with CKD.

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Title: Pharmacodynamics of vicadrostat for aldosterone synthase inhibition in patients with CKD.
Authors: Gashaw IA; Experimental Medicine Cardiovascular, Renal and Metabolic, Boehringer Ingelheim Pharma GmbH & Co. KG, 55216 Ingelheim am Rhein, Germany., Tuttle KR; Providence Medical Research Center, Providence Inland Northwest Health, Spokane, WA 99204, United States.; Division of Nephrology and Kidney Research Institute, University of Washington, Seattle, WA 98195, United States., Monroy Kuhn M; Experimental Medicine Biomarker Platforms, Boehringer Ingelheim Pharma GmbH & Co. KG, 88397 Biberach a. d. Riss, Germany., Pleiner S; Experimental Medicine Biomarker Platforms, Boehringer Ingelheim Pharma GmbH & Co. KG, 88397 Biberach a. d. Riss, Germany., Delic D; Experimental Medicine Biomarker Platforms, Boehringer Ingelheim Pharma GmbH & Co. KG, 88397 Biberach a. d. Riss, Germany.; Vth Department of Medicine, University Medical Center Mannheim, Heidelberg University, 68167 Heidelberg, Germany., Cronin L; Global Clinical Development Cardiovascular, Renal and Metabolic, Boehringer Ingelheim Pharmaceuticals, Inc., Ridgefield, CT 06877, United States., Shah SV; Global Clinical Development Cardiovascular, Renal and Metabolic, Boehringer Ingelheim Pharmaceuticals, Inc., Ridgefield, CT 06877, United States., Rossing P; Department of Clinical and Translational Research, Steno Diabetes Center Copenhagen, 2730 Herlev, Denmark.; Department of Clinical Medicine, University of Copenhagen, 2200 Copenhagen, Denmark.
Source: European journal of endocrinology [Eur J Endocrinol] 2026 Jan 06; Vol. 194 (1), pp. 46-57.
Publication Type: Journal Article; Randomized Controlled Trial; Clinical Trial, Phase II
Journal Info: Publisher: Oxford University Press Country of Publication: England NLM ID: 9423848 Publication Model: Print Cited Medium: Internet ISSN: 1479-683X (Electronic) Linking ISSN: 08044643 NLM ISO Abbreviation: Eur J Endocrinol Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Pharmacodynamics of vicadrostat for aldosterone synthase inhibition in patients with CKD.
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  Data: <searchLink fieldCode="AU" term="%22Gashaw+IA%22">Gashaw IA</searchLink>; Experimental Medicine Cardiovascular, Renal and Metabolic, Boehringer Ingelheim Pharma GmbH & Co. KG, 55216 Ingelheim am Rhein, Germany.<br /><searchLink fieldCode="AU" term="%22Tuttle+KR%22">Tuttle KR</searchLink>; Providence Medical Research Center, Providence Inland Northwest Health, Spokane, WA 99204, United States.; Division of Nephrology and Kidney Research Institute, University of Washington, Seattle, WA 98195, United States.<br /><searchLink fieldCode="AU" term="%22Monroy+Kuhn+M%22">Monroy Kuhn M</searchLink>; Experimental Medicine Biomarker Platforms, Boehringer Ingelheim Pharma GmbH & Co. KG, 88397 Biberach a. d. Riss, Germany.<br /><searchLink fieldCode="AU" term="%22Pleiner+S%22">Pleiner S</searchLink>; Experimental Medicine Biomarker Platforms, Boehringer Ingelheim Pharma GmbH & Co. KG, 88397 Biberach a. d. Riss, Germany.<br /><searchLink fieldCode="AU" term="%22Delic+D%22">Delic D</searchLink>; Experimental Medicine Biomarker Platforms, Boehringer Ingelheim Pharma GmbH & Co. KG, 88397 Biberach a. d. Riss, Germany.; Vth Department of Medicine, University Medical Center Mannheim, Heidelberg University, 68167 Heidelberg, Germany.<br /><searchLink fieldCode="AU" term="%22Cronin+L%22">Cronin L</searchLink>; Global Clinical Development Cardiovascular, Renal and Metabolic, Boehringer Ingelheim Pharmaceuticals, Inc., Ridgefield, CT 06877, United States.<br /><searchLink fieldCode="AU" term="%22Shah+SV%22">Shah SV</searchLink>; Global Clinical Development Cardiovascular, Renal and Metabolic, Boehringer Ingelheim Pharmaceuticals, Inc., Ridgefield, CT 06877, United States.<br /><searchLink fieldCode="AU" term="%22Rossing+P%22">Rossing P</searchLink>; Department of Clinical and Translational Research, Steno Diabetes Center Copenhagen, 2730 Herlev, Denmark.; Department of Clinical Medicine, University of Copenhagen, 2200 Copenhagen, Denmark.
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  Data: <searchLink fieldCode="JN" term="%229423848%22">European journal of endocrinology</searchLink> [Eur J Endocrinol] 2026 Jan 06; Vol. 194 (1), pp. 46-57.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Oxford+University+Press%22">Oxford University Press </searchLink><i>Country of Publication: </i>England <i>NLM ID: </i>9423848 <i>Publication Model: </i>Print <i>Cited Medium: </i>Internet <i>ISSN: </i>1479-683X (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2208044643%22">08044643 </searchLink><i>NLM ISO Abbreviation: </i>Eur J Endocrinol <i>Subsets: </i>MEDLINE
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        Value: 10.1093/ejendo/lvaf265
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        Text: English
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      – TitleFull: Pharmacodynamics of vicadrostat for aldosterone synthase inhibition in patients with CKD.
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              Text: 2026 Jan 06
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