Risk factors associated to disability in primary headaches: a systematic review to inform future iterations of the Global Burden of Disease Study.

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Title: Risk factors associated to disability in primary headaches: a systematic review to inform future iterations of the Global Burden of Disease Study.
Authors: Raggi A; Neurology, Public Health and Disability Unit, Fondazione IRCCS Istituto Neurologico Carlo Besta, Via Celoria 11, 20133, Milan, Italy. alberto.raggi@istituto-besta.it., Castaldo M; Headache Centre, Department of Medicine and Surgery, University of Parma, Parma, Italy.; Clinical Psychophysiology and Clinical Neuropsychology Labs, University of Parma, Parma, Italy., Chiang CC; Department of Neurology, Mayo Clinic, Rochester, USA., Cho SJ; Department of Neurology, Dongtan Sacred Heart Hospital, Hallym University College of Medicine, Hwaseong, Korea., Chu MK; Department of Neurology, Yonsei University College of Medicine, Seoul, Korea., Della Pietra A; Department Molecular Physiology and Biophysics, Carver College of Medicine, University of Iowa, Iowa City, US., Holland PR; Headache Group, Wolfson Sensory Pain and Regeneration Centre, Institute of Psychiatry, Psychology and Neuroscience, King's College London, London, UK., Husøy AK; Department of Neuroscience and Movement Science, Norwegian University of Science and Technology Trondheim, Trondhei, Norway.; Department of Neurology, St Olavs University Hospital Neurology Clinic, Trondheim, Norway., Labastida-Ramírez A; Division of Neuroscience, Faculty of Biology, Medicine, and Health, University of Manchester, Manchester, UK.; Geoffrey Jefferson Brain Research Centre, Manchester Academic Health Science Centre, Northern Care Alliance NHS Foundation Trust, University of Manchester, Manchester, UK., Lytvyak E; Division of Preventive Medicine, Department of Medicine, University of Alberta, Edmonton, Canada., Messina R; Neurology Unit and Neuroimaging Research Unit, IRCCS San Raffaele Scientific Institute, Milan, Italy.; Vita-Salute San Raffaele University, Milan, Italy., Onan D; Department of Physiotherapy and Rehabilitation, Faculty of Health Sciences, Yozgat Bozok University, Yozgat, Turkey.; Department of Biotechnological and Applied Clinical Sciences, University of L'Aquila, L'Aquila, Italy., Onofri A; Department of Biotechnological and Applied Clinical Sciences, University of L'Aquila, L'Aquila, Italy., Ornello R; Department of Biotechnological and Applied Clinical Sciences, University of L'Aquila, L'Aquila, Italy., Pellesi L; Clinical Pharmacology, Pharmacy and Environmental Medicine, Department of Public Health, University of Southern Denmark, Odense, Denmark., Petrušič I; Laboratory for Advanced Analysis of Neuroimages, Faculty of Physical Chemistry, University of Belgrade, Belgrade, Serbia., Puledda F; Headache Group, Wolfson Sensory Pain and Regeneration Centre, Institute of Psychiatry, Psychology and Neuroscience, King's College London, London, UK.; National Institute for Health Research (NIHR) King's Clinical Research Facility, King's College London, London, UK., Raffaelli B; Department of Neurology, Charité - Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin and Humboldt-Universität zu Berlin, Berlin, Germany., Rubio-Beltrán E; Headache Group, Wolfson Sensory Pain and Regeneration Centre, Institute of Psychiatry, Psychology and Neuroscience, King's College London, London, UK., Ruscheweyh R; Department of Neurology, LMU University Hospital, LMU Munich, Munich, Germany., Scuteri D; Department of Health Sciences, University 'Magna Graecia' of Catanzaro, Catanzaro, Italy., Sebastianelli G; Department of Medico-Surgical Sciences and Biotechnologies, Sapienza University of Rome Polo Pontino, Latina, Italy., Straube S; Division of Preventive Medicine, Department of Medicine, University of Alberta, Edmonton, Canada.; School of Public Health, University of Alberta, Edmonton, Canada., Tana C; Internal Medicine Unit, Eastern Hospital, ASL Taranto, Taranto, Italy., Vuralli D; Department of Neurology and Algology, Neuropsychiatry Center, Neuroscience and Neurotechnology Center of Excellence (NÖROM), Faculty of Medicine Gazi University , Ankara, Turkey., Waliszewska-Prosół M; Department of Neurology, Wroclaw Medical University, Wroclaw, Poland., Wang W; Headache Center, Department of Neurology, Sir Run Run Shaw Hospital, School of Medicine, Zhejiang University, Hangzhou, China., Wells-Gatnik W; Texas Tech University Health Sciences Center, El Paso, USA., Woldeamanuel YW; Circadian-Migraine Lab, Department of Neurology, Mayo Clinic Arizona, Phoenix, USA.; Biobehavioral Pain Lab, Arizona State University, Phoenix, USA.; Datta Meghe Medical College, Nagpur, India.; Ex-Amplify Therapeutics Inc., San Diego, USA.; Advanced Clinical & Research Center, Addis Abeba, Ethiopia., Wu JW; Department of Neurology, Neurological Institute, Taipei Veterans General Hospital, Taipei, Taiwan., Yener SM; Migraine Foundation Australia, Melbourne, Victoria, Australia.; Department of Neurology, Monash Health, Melbourne, Victoria, Australia., Corso B; Neuroscience Institute, National Research Council (CNR), Padova, Italy., Martelletti P; Unitelma Sapienza University of Rome, Rome, Italy.
Source: The journal of headache and pain [J Headache Pain] 2025 Dec 23; Vol. 27 (1), pp. 9. Date of Electronic Publication: 2025 Dec 23.
Publication Type: Journal Article; Systematic Review; Review
Journal Info: Publisher: BioMed Central Country of Publication: England NLM ID: 100940562 Publication Model: Electronic Cited Medium: Internet ISSN: 1129-2377 (Electronic) Linking ISSN: 11292369 NLM ISO Abbreviation: J Headache Pain Subsets: MEDLINE
Database: MEDLINE Ultimate
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PubType: Academic Journal
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  Data: Risk factors associated to disability in primary headaches: a systematic review to inform future iterations of the Global Burden of Disease Study.
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  Data: <searchLink fieldCode="AU" term="%22Raggi+A%22">Raggi A</searchLink>; Neurology, Public Health and Disability Unit, Fondazione IRCCS Istituto Neurologico Carlo Besta, Via Celoria 11, 20133, Milan, Italy. alberto.raggi@istituto-besta.it.<br /><searchLink fieldCode="AU" term="%22Castaldo+M%22">Castaldo M</searchLink>; Headache Centre, Department of Medicine and Surgery, University of Parma, Parma, Italy.; Clinical Psychophysiology and Clinical Neuropsychology Labs, University of Parma, Parma, Italy.<br /><searchLink fieldCode="AU" term="%22Chiang+CC%22">Chiang CC</searchLink>; Department of Neurology, Mayo Clinic, Rochester, USA.<br /><searchLink fieldCode="AU" term="%22Cho+SJ%22">Cho SJ</searchLink>; Department of Neurology, Dongtan Sacred Heart Hospital, Hallym University College of Medicine, Hwaseong, Korea.<br /><searchLink fieldCode="AU" term="%22Chu+MK%22">Chu MK</searchLink>; Department of Neurology, Yonsei University College of Medicine, Seoul, Korea.<br /><searchLink fieldCode="AU" term="%22Della+Pietra+A%22">Della Pietra A</searchLink>; Department Molecular Physiology and Biophysics, Carver College of Medicine, University of Iowa, Iowa City, US.<br /><searchLink fieldCode="AU" term="%22Holland+PR%22">Holland PR</searchLink>; Headache Group, Wolfson Sensory Pain and Regeneration Centre, Institute of Psychiatry, Psychology and Neuroscience, King's College London, London, UK.<br /><searchLink fieldCode="AU" term="%22Husøy+AK%22">Husøy AK</searchLink>; Department of Neuroscience and Movement Science, Norwegian University of Science and Technology Trondheim, Trondhei, Norway.; Department of Neurology, St Olavs University Hospital Neurology Clinic, Trondheim, Norway.<br /><searchLink fieldCode="AU" term="%22Labastida-Ramírez+A%22">Labastida-Ramírez A</searchLink>; Division of Neuroscience, Faculty of Biology, Medicine, and Health, University of Manchester, Manchester, UK.; Geoffrey Jefferson Brain Research Centre, Manchester Academic Health Science Centre, Northern Care Alliance NHS Foundation Trust, University of Manchester, Manchester, UK.<br /><searchLink fieldCode="AU" term="%22Lytvyak+E%22">Lytvyak E</searchLink>; Division of Preventive Medicine, Department of Medicine, University of Alberta, Edmonton, Canada.<br /><searchLink fieldCode="AU" term="%22Messina+R%22">Messina R</searchLink>; Neurology Unit and Neuroimaging Research Unit, IRCCS San Raffaele Scientific Institute, Milan, Italy.; Vita-Salute San Raffaele University, Milan, Italy.<br /><searchLink fieldCode="AU" term="%22Onan+D%22">Onan D</searchLink>; Department of Physiotherapy and Rehabilitation, Faculty of Health Sciences, Yozgat Bozok University, Yozgat, Turkey.; Department of Biotechnological and Applied Clinical Sciences, University of L'Aquila, L'Aquila, Italy.<br /><searchLink fieldCode="AU" term="%22Onofri+A%22">Onofri A</searchLink>; Department of Biotechnological and Applied Clinical Sciences, University of L'Aquila, L'Aquila, Italy.<br /><searchLink fieldCode="AU" term="%22Ornello+R%22">Ornello R</searchLink>; Department of Biotechnological and Applied Clinical Sciences, University of L'Aquila, L'Aquila, Italy.<br /><searchLink fieldCode="AU" term="%22Pellesi+L%22">Pellesi L</searchLink>; Clinical Pharmacology, Pharmacy and Environmental Medicine, Department of Public Health, University of Southern Denmark, Odense, Denmark.<br /><searchLink fieldCode="AU" term="%22Petrušič+I%22">Petrušič I</searchLink>; Laboratory for Advanced Analysis of Neuroimages, Faculty of Physical Chemistry, University of Belgrade, Belgrade, Serbia.<br /><searchLink fieldCode="AU" term="%22Puledda+F%22">Puledda F</searchLink>; Headache Group, Wolfson Sensory Pain and Regeneration Centre, Institute of Psychiatry, Psychology and Neuroscience, King's College London, London, UK.; National Institute for Health Research (NIHR) King's Clinical Research Facility, King's College London, London, UK.<br /><searchLink fieldCode="AU" term="%22Raffaelli+B%22">Raffaelli B</searchLink>; Department of Neurology, Charité - Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin and Humboldt-Universität zu Berlin, Berlin, Germany.<br /><searchLink fieldCode="AU" term="%22Rubio-Beltrán+E%22">Rubio-Beltrán E</searchLink>; Headache Group, Wolfson Sensory Pain and Regeneration Centre, Institute of Psychiatry, Psychology and Neuroscience, King's College London, London, UK.<br /><searchLink fieldCode="AU" term="%22Ruscheweyh+R%22">Ruscheweyh R</searchLink>; Department of Neurology, LMU University Hospital, LMU Munich, Munich, Germany.<br /><searchLink fieldCode="AU" term="%22Scuteri+D%22">Scuteri D</searchLink>; Department of Health Sciences, University 'Magna Graecia' of Catanzaro, Catanzaro, Italy.<br /><searchLink fieldCode="AU" term="%22Sebastianelli+G%22">Sebastianelli G</searchLink>; Department of Medico-Surgical Sciences and Biotechnologies, Sapienza University of Rome Polo Pontino, Latina, Italy.<br /><searchLink fieldCode="AU" term="%22Straube+S%22">Straube S</searchLink>; Division of Preventive Medicine, Department of Medicine, University of Alberta, Edmonton, Canada.; School of Public Health, University of Alberta, Edmonton, Canada.<br /><searchLink fieldCode="AU" term="%22Tana+C%22">Tana C</searchLink>; Internal Medicine Unit, Eastern Hospital, ASL Taranto, Taranto, Italy.<br /><searchLink fieldCode="AU" term="%22Vuralli+D%22">Vuralli D</searchLink>; Department of Neurology and Algology, Neuropsychiatry Center, Neuroscience and Neurotechnology Center of Excellence (NÖROM), Faculty of Medicine Gazi University , Ankara, Turkey.<br /><searchLink fieldCode="AU" term="%22Waliszewska-Prosół+M%22">Waliszewska-Prosół M</searchLink>; Department of Neurology, Wroclaw Medical University, Wroclaw, Poland.<br /><searchLink fieldCode="AU" term="%22Wang+W%22">Wang W</searchLink>; Headache Center, Department of Neurology, Sir Run Run Shaw Hospital, School of Medicine, Zhejiang University, Hangzhou, China.<br /><searchLink fieldCode="AU" term="%22Wells-Gatnik+W%22">Wells-Gatnik W</searchLink>; Texas Tech University Health Sciences Center, El Paso, USA.<br /><searchLink fieldCode="AU" term="%22Woldeamanuel+YW%22">Woldeamanuel YW</searchLink>; Circadian-Migraine Lab, Department of Neurology, Mayo Clinic Arizona, Phoenix, USA.; Biobehavioral Pain Lab, Arizona State University, Phoenix, USA.; Datta Meghe Medical College, Nagpur, India.; Ex-Amplify Therapeutics Inc., San Diego, USA.; Advanced Clinical & Research Center, Addis Abeba, Ethiopia.<br /><searchLink fieldCode="AU" term="%22Wu+JW%22">Wu JW</searchLink>; Department of Neurology, Neurological Institute, Taipei Veterans General Hospital, Taipei, Taiwan.<br /><searchLink fieldCode="AU" term="%22Yener+SM%22">Yener SM</searchLink>; Migraine Foundation Australia, Melbourne, Victoria, Australia.; Department of Neurology, Monash Health, Melbourne, Victoria, Australia.<br /><searchLink fieldCode="AU" term="%22Corso+B%22">Corso B</searchLink>; Neuroscience Institute, National Research Council (CNR), Padova, Italy.<br /><searchLink fieldCode="AU" term="%22Martelletti+P%22">Martelletti P</searchLink>; Unitelma Sapienza University of Rome, Rome, Italy.
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  Data: <searchLink fieldCode="JN" term="%22100940562%22">The journal of headache and pain</searchLink> [J Headache Pain] 2025 Dec 23; Vol. 27 (1), pp. 9. <i>Date of Electronic Publication: </i>2025 Dec 23.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22BioMed+Central%22">BioMed Central </searchLink><i>Country of Publication: </i>England <i>NLM ID: </i>100940562 <i>Publication Model: </i>Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1129-2377 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2211292369%22">11292369 </searchLink><i>NLM ISO Abbreviation: </i>J Headache Pain <i>Subsets: </i>MEDLINE
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