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Enhanced overall and progression-free survival in advanced melanoma patients undergoing targeted therapy alongside antithrombotic treatment - Insights from a multicenter study involving 1296 patients from the prospective skin cancer registry ADOReg.

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Title: Enhanced overall and progression-free survival in advanced melanoma patients undergoing targeted therapy alongside antithrombotic treatment - Insights from a multicenter study involving 1296 patients from the prospective skin cancer registry ADOReg.
Authors: Zimmermann N; Department of Dermatology and Venereology, University Medical Center Hamburg-Eppendorf (UKE), Hamburg, Germany; Fleur Hiege Center for Skin Cancer Research, University Medical Center Hamburg-Eppendorf (UKE), Hamburg, Germany., Kött J; Department of Dermatology and Venereology, University Medical Center Hamburg-Eppendorf (UKE), Hamburg, Germany; Fleur Hiege Center for Skin Cancer Research, University Medical Center Hamburg-Eppendorf (UKE), Hamburg, Germany. Electronic address: j.koett@uke.de., Zell T; Department of Dermatology and Venereology, University Medical Center Hamburg-Eppendorf (UKE), Hamburg, Germany; Fleur Hiege Center for Skin Cancer Research, University Medical Center Hamburg-Eppendorf (UKE), Hamburg, Germany., Abedini AZ; Department of Dermatology and Venereology, University Medical Center Hamburg-Eppendorf (UKE), Hamburg, Germany; Fleur Hiege Center for Skin Cancer Research, University Medical Center Hamburg-Eppendorf (UKE), Hamburg, Germany., Blomen CL; Department of Dermatology and Venereology, University Medical Center Hamburg-Eppendorf (UKE), Hamburg, Germany; Fleur Hiege Center for Skin Cancer Research, University Medical Center Hamburg-Eppendorf (UKE), Hamburg, Germany., Belz S; Department of Dermatology and Venereology, University Medical Center Hamburg-Eppendorf (UKE), Hamburg, Germany; Fleur Hiege Center for Skin Cancer Research, University Medical Center Hamburg-Eppendorf (UKE), Hamburg, Germany., Deitert B; Department of Dermatology and Venereology, University Medical Center Hamburg-Eppendorf (UKE), Hamburg, Germany; Fleur Hiege Center for Skin Cancer Research, University Medical Center Hamburg-Eppendorf (UKE), Hamburg, Germany., Heidrich I; Department of Dermatology and Venereology, University Medical Center Hamburg-Eppendorf (UKE), Hamburg, Germany; Fleur Hiege Center for Skin Cancer Research, University Medical Center Hamburg-Eppendorf (UKE), Hamburg, Germany; Institute of Tumor Biology, University Medical Center Hamburg-Eppendorf (UKE), Hamburg, Germany., Geidel G; Department of Dermatology and Venereology, University Medical Center Hamburg-Eppendorf (UKE), Hamburg, Germany; Fleur Hiege Center for Skin Cancer Research, University Medical Center Hamburg-Eppendorf (UKE), Hamburg, Germany., Rünger A; Department of Dermatology and Venereology, University Medical Center Hamburg-Eppendorf (UKE), Hamburg, Germany; Fleur Hiege Center for Skin Cancer Research, University Medical Center Hamburg-Eppendorf (UKE), Hamburg, Germany., Smit DJ; Fleur Hiege Center for Skin Cancer Research, University Medical Center Hamburg-Eppendorf (UKE), Hamburg, Germany; Institute of Tumor Biology, University Medical Center Hamburg-Eppendorf (UKE), Hamburg, Germany., Weichenthal M; Department of Dermatology, University Hospital of Schleswig-Holstein, Kiel, Germany., Ugurel S; Department of Dermatolog, Bielefeld University, Bielefeld, Germany; Medical School and University Medical Center OWL, Bielefeld, Germany., Leiter U; Department of Dermatology, Division of Dermatooncology, University Medical Center, Tuebingen, Germany., Berking C; Department of Dermatology, Comprehensive Cancer Center Erlangen - EMN, Erlangen, Germany; Friedrich-Alexander University Erlangen-Nürnberg (FAU), Erlangen, Germany., Gutzmer R; Department of Dermatology, Johannes Wesling Medical Center, Minden, Germany; Ruhr University Bochum, Minden, Germany., Schadendorf D; Department of Dermatology, University Hospital Essen, University of Duisburg-Essen, Essen, Germany; German Cancer Consortium (DKTK), German Cancer Consortium (DKTK), Essen, Düsseldorf, Germany; National Center for Tumor Disease (NCT-West), Campus Essen, Essen, Germany; Research Alliance Ruhr, Research Center One Health, University Duisburg-Essen, Campus Essen, Essen, Germany., von Wasielewski I; Department of Dermatology and Allergy, Skin Cancer Center Hannover, Hannover, Germany., Mohr P; Elbe Clinic Buxtehude, Buxtehude, Germany., Meier F; Department of Dermatology, Faculty of Medicine and University Hospital Carl Gustav Carus, Dresden, Germany; Skin Cancer Center at the University Cancer Centre Dresden and National Center for Tumor Diseases, Dresden, Germany., Herbst R; Helios Skin Cancer Center, Helios Klinikum Erfurt, Erfurt, Germany., Utikal J; Skin Cancer Unit, German Cancer Research Center (DKFZ), Heidelberg, Germany; Department of Dermatology, University Medical Center Mannheim, Mannheim, Germany; Ruprecht-Karl University of Heidelberg, Mannheim, Germany; DKFZ Hector Cancer Institute at the University Medical Center Mannheim, Mannheim, Germany., Terheyden P; Department of Dermatology, University of Lübeck, Lübeck, Germany., Haferkamp S; Department of Dermatology, University Hospital Regensburg, Regensburg, Germany; Bavarian Center for Cancer Research (BZKF), Germany., Pföhler C; Department of Dermatology, Saarland University Medical School, Hombur, Saar, Germany., Kaatz M; Department of Dermatology, SRH Wald-Klinikum Gera GmbH, Gera, Germany; Department of Dermatology, DRK Krankenhaus Rabenstein, Chemnitz, Germany., Ziller F; Department of Dermatology, DRK Krankenhaus Rabenstein, Chemnitz, Germany., Ulrich J; Department of Dermatology and Skin Cancer Center, Quedlinburg, Germany., Meiss F; Department of Dermatology, Medical Center - University of Freiburg, Freiburg, Germany; University of Freiburg, Freiburg, Germany., Bauer AT; Department of Dermatology and Venereology, University Medical Center Hamburg-Eppendorf (UKE), Hamburg, Germany; Fleur Hiege Center for Skin Cancer Research, University Medical Center Hamburg-Eppendorf (UKE), Hamburg, Germany., Schneider SW; Department of Dermatology and Venereology, University Medical Center Hamburg-Eppendorf (UKE), Hamburg, Germany; Fleur Hiege Center for Skin Cancer Research, University Medical Center Hamburg-Eppendorf (UKE), Hamburg, Germany., Gebhardt C; Department of Dermatology and Venereology, University Medical Center Hamburg-Eppendorf (UKE), Hamburg, Germany; Fleur Hiege Center for Skin Cancer Research, University Medical Center Hamburg-Eppendorf (UKE), Hamburg, Germany. Electronic address: ch.gebhardt@uke.de.
Source: European journal of cancer (Oxford, England : 1990) [Eur J Cancer] 2026 Feb 05; Vol. 234, pp. 116195. Date of Electronic Publication: 2025 Dec 19.
Publication Type: Journal Article; Multicenter Study
Journal Info: Publisher: Elsevier Science Ltd Country of Publication: England NLM ID: 9005373 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1879-0852 (Electronic) Linking ISSN: 09598049 NLM ISO Abbreviation: Eur J Cancer Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Enhanced overall and progression-free survival in advanced melanoma patients undergoing targeted therapy alongside antithrombotic treatment - Insights from a multicenter study involving 1296 patients from the prospective skin cancer registry ADOReg.
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  Data: <searchLink fieldCode="AU" term="%22Zimmermann+N%22">Zimmermann N</searchLink>; Department of Dermatology and Venereology, University Medical Center Hamburg-Eppendorf (UKE), Hamburg, Germany; Fleur Hiege Center for Skin Cancer Research, University Medical Center Hamburg-Eppendorf (UKE), Hamburg, Germany.<br /><searchLink fieldCode="AU" term="%22Kött+J%22">Kött J</searchLink>; Department of Dermatology and Venereology, University Medical Center Hamburg-Eppendorf (UKE), Hamburg, Germany; Fleur Hiege Center for Skin Cancer Research, University Medical Center Hamburg-Eppendorf (UKE), Hamburg, Germany. Electronic address: j.koett@uke.de.<br /><searchLink fieldCode="AU" term="%22Zell+T%22">Zell T</searchLink>; Department of Dermatology and Venereology, University Medical Center Hamburg-Eppendorf (UKE), Hamburg, Germany; Fleur Hiege Center for Skin Cancer Research, University Medical Center Hamburg-Eppendorf (UKE), Hamburg, Germany.<br /><searchLink fieldCode="AU" term="%22Abedini+AZ%22">Abedini AZ</searchLink>; Department of Dermatology and Venereology, University Medical Center Hamburg-Eppendorf (UKE), Hamburg, Germany; Fleur Hiege Center for Skin Cancer Research, University Medical Center Hamburg-Eppendorf (UKE), Hamburg, Germany.<br /><searchLink fieldCode="AU" term="%22Blomen+CL%22">Blomen CL</searchLink>; Department of Dermatology and Venereology, University Medical Center Hamburg-Eppendorf (UKE), Hamburg, Germany; Fleur Hiege Center for Skin Cancer Research, University Medical Center Hamburg-Eppendorf (UKE), Hamburg, Germany.<br /><searchLink fieldCode="AU" term="%22Belz+S%22">Belz S</searchLink>; Department of Dermatology and Venereology, University Medical Center Hamburg-Eppendorf (UKE), Hamburg, Germany; Fleur Hiege Center for Skin Cancer Research, University Medical Center Hamburg-Eppendorf (UKE), Hamburg, Germany.<br /><searchLink fieldCode="AU" term="%22Deitert+B%22">Deitert B</searchLink>; Department of Dermatology and Venereology, University Medical Center Hamburg-Eppendorf (UKE), Hamburg, Germany; Fleur Hiege Center for Skin Cancer Research, University Medical Center Hamburg-Eppendorf (UKE), Hamburg, Germany.<br /><searchLink fieldCode="AU" term="%22Heidrich+I%22">Heidrich I</searchLink>; Department of Dermatology and Venereology, University Medical Center Hamburg-Eppendorf (UKE), Hamburg, Germany; Fleur Hiege Center for Skin Cancer Research, University Medical Center Hamburg-Eppendorf (UKE), Hamburg, Germany; Institute of Tumor Biology, University Medical Center Hamburg-Eppendorf (UKE), Hamburg, Germany.<br /><searchLink fieldCode="AU" term="%22Geidel+G%22">Geidel G</searchLink>; Department of Dermatology and Venereology, University Medical Center Hamburg-Eppendorf (UKE), Hamburg, Germany; Fleur Hiege Center for Skin Cancer Research, University Medical Center Hamburg-Eppendorf (UKE), Hamburg, Germany.<br /><searchLink fieldCode="AU" term="%22Rünger+A%22">Rünger A</searchLink>; Department of Dermatology and Venereology, University Medical Center Hamburg-Eppendorf (UKE), Hamburg, Germany; Fleur Hiege Center for Skin Cancer Research, University Medical Center Hamburg-Eppendorf (UKE), Hamburg, Germany.<br /><searchLink fieldCode="AU" term="%22Smit+DJ%22">Smit DJ</searchLink>; Fleur Hiege Center for Skin Cancer Research, University Medical Center Hamburg-Eppendorf (UKE), Hamburg, Germany; Institute of Tumor Biology, University Medical Center Hamburg-Eppendorf (UKE), Hamburg, Germany.<br /><searchLink fieldCode="AU" term="%22Weichenthal+M%22">Weichenthal M</searchLink>; Department of Dermatology, University Hospital of Schleswig-Holstein, Kiel, Germany.<br /><searchLink fieldCode="AU" term="%22Ugurel+S%22">Ugurel S</searchLink>; Department of Dermatolog, Bielefeld University, Bielefeld, Germany; Medical School and University Medical Center OWL, Bielefeld, Germany.<br /><searchLink fieldCode="AU" term="%22Leiter+U%22">Leiter U</searchLink>; Department of Dermatology, Division of Dermatooncology, University Medical Center, Tuebingen, Germany.<br /><searchLink fieldCode="AU" term="%22Berking+C%22">Berking C</searchLink>; Department of Dermatology, Comprehensive Cancer Center Erlangen - EMN, Erlangen, Germany; Friedrich-Alexander University Erlangen-Nürnberg (FAU), Erlangen, Germany.<br /><searchLink fieldCode="AU" term="%22Gutzmer+R%22">Gutzmer R</searchLink>; Department of Dermatology, Johannes Wesling Medical Center, Minden, Germany; Ruhr University Bochum, Minden, Germany.<br /><searchLink fieldCode="AU" term="%22Schadendorf+D%22">Schadendorf D</searchLink>; Department of Dermatology, University Hospital Essen, University of Duisburg-Essen, Essen, Germany; German Cancer Consortium (DKTK), German Cancer Consortium (DKTK), Essen, Düsseldorf, Germany; National Center for Tumor Disease (NCT-West), Campus Essen, Essen, Germany; Research Alliance Ruhr, Research Center One Health, University Duisburg-Essen, Campus Essen, Essen, Germany.<br /><searchLink fieldCode="AU" term="%22von+Wasielewski+I%22">von Wasielewski I</searchLink>; Department of Dermatology and Allergy, Skin Cancer Center Hannover, Hannover, Germany.<br /><searchLink fieldCode="AU" term="%22Mohr+P%22">Mohr P</searchLink>; Elbe Clinic Buxtehude, Buxtehude, Germany.<br /><searchLink fieldCode="AU" term="%22Meier+F%22">Meier F</searchLink>; Department of Dermatology, Faculty of Medicine and University Hospital Carl Gustav Carus, Dresden, Germany; Skin Cancer Center at the University Cancer Centre Dresden and National Center for Tumor Diseases, Dresden, Germany.<br /><searchLink fieldCode="AU" term="%22Herbst+R%22">Herbst R</searchLink>; Helios Skin Cancer Center, Helios Klinikum Erfurt, Erfurt, Germany.<br /><searchLink fieldCode="AU" term="%22Utikal+J%22">Utikal J</searchLink>; Skin Cancer Unit, German Cancer Research Center (DKFZ), Heidelberg, Germany; Department of Dermatology, University Medical Center Mannheim, Mannheim, Germany; Ruprecht-Karl University of Heidelberg, Mannheim, Germany; DKFZ Hector Cancer Institute at the University Medical Center Mannheim, Mannheim, Germany.<br /><searchLink fieldCode="AU" term="%22Terheyden+P%22">Terheyden P</searchLink>; Department of Dermatology, University of Lübeck, Lübeck, Germany.<br /><searchLink fieldCode="AU" term="%22Haferkamp+S%22">Haferkamp S</searchLink>; Department of Dermatology, University Hospital Regensburg, Regensburg, Germany; Bavarian Center for Cancer Research (BZKF), Germany.<br /><searchLink fieldCode="AU" term="%22Pföhler+C%22">Pföhler C</searchLink>; Department of Dermatology, Saarland University Medical School, Hombur, Saar, Germany.<br /><searchLink fieldCode="AU" term="%22Kaatz+M%22">Kaatz M</searchLink>; Department of Dermatology, SRH Wald-Klinikum Gera GmbH, Gera, Germany; Department of Dermatology, DRK Krankenhaus Rabenstein, Chemnitz, Germany.<br /><searchLink fieldCode="AU" term="%22Ziller+F%22">Ziller F</searchLink>; Department of Dermatology, DRK Krankenhaus Rabenstein, Chemnitz, Germany.<br /><searchLink fieldCode="AU" term="%22Ulrich+J%22">Ulrich J</searchLink>; Department of Dermatology and Skin Cancer Center, Quedlinburg, Germany.<br /><searchLink fieldCode="AU" term="%22Meiss+F%22">Meiss F</searchLink>; Department of Dermatology, Medical Center - University of Freiburg, Freiburg, Germany; University of Freiburg, Freiburg, Germany.<br /><searchLink fieldCode="AU" term="%22Bauer+AT%22">Bauer AT</searchLink>; Department of Dermatology and Venereology, University Medical Center Hamburg-Eppendorf (UKE), Hamburg, Germany; Fleur Hiege Center for Skin Cancer Research, University Medical Center Hamburg-Eppendorf (UKE), Hamburg, Germany.<br /><searchLink fieldCode="AU" term="%22Schneider+SW%22">Schneider SW</searchLink>; Department of Dermatology and Venereology, University Medical Center Hamburg-Eppendorf (UKE), Hamburg, Germany; Fleur Hiege Center for Skin Cancer Research, University Medical Center Hamburg-Eppendorf (UKE), Hamburg, Germany.<br /><searchLink fieldCode="AU" term="%22Gebhardt+C%22">Gebhardt C</searchLink>; Department of Dermatology and Venereology, University Medical Center Hamburg-Eppendorf (UKE), Hamburg, Germany; Fleur Hiege Center for Skin Cancer Research, University Medical Center Hamburg-Eppendorf (UKE), Hamburg, Germany. Electronic address: ch.gebhardt@uke.de.
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