Stimulant medications affect arousal and reward, not attention networks.

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Title: Stimulant medications affect arousal and reward, not attention networks.
Authors: Kay BP; Department of Neurology, Washington University School of Medicine, St. Louis, MO, USA; Allied Labs for Imaging Guided Neurotherapies (ALIGN), Washington University School of Medicine, St. Louis, MO, USA. Electronic address: benjamin.kay@wustl.edu., Wheelock MD; Mallinckrodt Institute of Radiology, Washington University School of Medicine, St. Louis, MO, USA., Siegel JS; Department of Psychiatry, New York University Langone Center for Psychedelic Medicine, New York, NY, USA., Raut RV; Mallinckrodt Institute of Radiology, Washington University School of Medicine, St. Louis, MO, USA; Allen Institute, Seattle, WA, USA; Department of Physiology & Biophysics, University of Washington, Seattle, WA, USA., Chauvin RJ; Department of Neurology, Washington University School of Medicine, St. Louis, MO, USA; Allied Labs for Imaging Guided Neurotherapies (ALIGN), Washington University School of Medicine, St. Louis, MO, USA., Metoki A; Department of Neurology, Washington University School of Medicine, St. Louis, MO, USA; Allied Labs for Imaging Guided Neurotherapies (ALIGN), Washington University School of Medicine, St. Louis, MO, USA., Rajesh A; Allied Labs for Imaging Guided Neurotherapies (ALIGN), Washington University School of Medicine, St. Louis, MO, USA; Mallinckrodt Institute of Radiology, Washington University School of Medicine, St. Louis, MO, USA., Eck A; Mallinckrodt Institute of Radiology, Washington University School of Medicine, St. Louis, MO, USA., Pollaro J; Mallinckrodt Institute of Radiology, Washington University School of Medicine, St. Louis, MO, USA., Wang A; Department of Neurology, Washington University School of Medicine, St. Louis, MO, USA; Allied Labs for Imaging Guided Neurotherapies (ALIGN), Washington University School of Medicine, St. Louis, MO, USA., Suljic V; Department of Neurology, Washington University School of Medicine, St. Louis, MO, USA; Allied Labs for Imaging Guided Neurotherapies (ALIGN), Washington University School of Medicine, St. Louis, MO, USA., Adeyemo B; Department of Neurology, Washington University School of Medicine, St. Louis, MO, USA; Allied Labs for Imaging Guided Neurotherapies (ALIGN), Washington University School of Medicine, St. Louis, MO, USA., Baden NJ; Department of Neurology, Washington University School of Medicine, St. Louis, MO, USA; Allied Labs for Imaging Guided Neurotherapies (ALIGN), Washington University School of Medicine, St. Louis, MO, USA., Scheidter KM; Department of Neurology, Washington University School of Medicine, St. Louis, MO, USA; Allied Labs for Imaging Guided Neurotherapies (ALIGN), Washington University School of Medicine, St. Louis, MO, USA., Monk JS; Department of Neurology, Washington University School of Medicine, St. Louis, MO, USA; Allied Labs for Imaging Guided Neurotherapies (ALIGN), Washington University School of Medicine, St. Louis, MO, USA., Whiting FI; Department of Neurology, Washington University School of Medicine, St. Louis, MO, USA; Allied Labs for Imaging Guided Neurotherapies (ALIGN), Washington University School of Medicine, St. Louis, MO, USA., Ramirez-Perez N; Department of Neurology, Washington University School of Medicine, St. Louis, MO, USA; Allied Labs for Imaging Guided Neurotherapies (ALIGN), Washington University School of Medicine, St. Louis, MO, USA; Taylor Family Department of Neurosurgery, Washington University School of Medicine, St Louis, MO, USA., Krimmel SR; Department of Neurology, Washington University School of Medicine, St. Louis, MO, USA; Allied Labs for Imaging Guided Neurotherapies (ALIGN), Washington University School of Medicine, St. Louis, MO, USA., Shinohara RT; Penn Statistics in Imaging and Visualization Center, Perelman School of Medicine, Philadelphia, PA, USA; Department of Biostatistics, Epidemiology and Informatics, Perelman School of Medicine, Philadelphia, PA, USA; Center for AI and Data Science for Integrated Diagnostics, Perelman School of Medicine, Philadelphia, PA, USA., Tervo-Clemmens B; Department of Psychiatry and Behavioral Sciences, University of Minnesota, Minneapolis, MN, USA; Masonic Institute for the Developing Brain, University of Minnesota Medical School, Minneapolis, MN, USA., Hermosillo RJM; Masonic Institute for the Developing Brain, University of Minnesota Medical School, Minneapolis, MN, USA; Department of Pediatrics, University of Minnesota, Minneapolis, MN, USA., Nelson SM; Masonic Institute for the Developing Brain, University of Minnesota Medical School, Minneapolis, MN, USA; Department of Pediatrics, University of Minnesota, Minneapolis, MN, USA., Hendrickson TJ; Masonic Institute for the Developing Brain, University of Minnesota Medical School, Minneapolis, MN, USA; Minnesota Supercomputing Institute, University of Minnesota, Minneapolis, MN, USA., Madison T; Masonic Institute for the Developing Brain, University of Minnesota Medical School, Minneapolis, MN, USA; Department of Pediatrics, University of Minnesota, Minneapolis, MN, USA., Moore LA; Masonic Institute for the Developing Brain, University of Minnesota Medical School, Minneapolis, MN, USA., Miranda-Domínguez Ó; Masonic Institute for the Developing Brain, University of Minnesota Medical School, Minneapolis, MN, USA; Department of Pediatrics, University of Minnesota, Minneapolis, MN, USA., Randolph A; Masonic Institute for the Developing Brain, University of Minnesota Medical School, Minneapolis, MN, USA; Department of Psychiatry, Washington University School of Medicine, St. Louis, MO, USA., Feczko E; Masonic Institute for the Developing Brain, University of Minnesota Medical School, Minneapolis, MN, USA; Department of Pediatrics, University of Minnesota, Minneapolis, MN, USA., Roland JL; Allied Labs for Imaging Guided Neurotherapies (ALIGN), Washington University School of Medicine, St. Louis, MO, USA; Taylor Family Department of Neurosurgery, Washington University School of Medicine, St Louis, MO, USA., Nicol GE; Allied Labs for Imaging Guided Neurotherapies (ALIGN), Washington University School of Medicine, St. Louis, MO, USA; Department of Psychiatry, Washington University School of Medicine, St. Louis, MO, USA., Laumann TO; Allied Labs for Imaging Guided Neurotherapies (ALIGN), Washington University School of Medicine, St. Louis, MO, USA; Mallinckrodt Institute of Radiology, Washington University School of Medicine, St. Louis, MO, USA; Department of Psychiatry, Washington University School of Medicine, St. Louis, MO, USA., Marek S; Allied Labs for Imaging Guided Neurotherapies (ALIGN), Washington University School of Medicine, St. Louis, MO, USA; Mallinckrodt Institute of Radiology, Washington University School of Medicine, St. Louis, MO, USA., Gordon EM; Allied Labs for Imaging Guided Neurotherapies (ALIGN), Washington University School of Medicine, St. Louis, MO, USA; Mallinckrodt Institute of Radiology, Washington University School of Medicine, St. Louis, MO, USA., Raichle ME; Department of Neurology, Washington University School of Medicine, St. Louis, MO, USA; Mallinckrodt Institute of Radiology, Washington University School of Medicine, St. Louis, MO, USA; Department of Biomedical Engineering, Washington University in St. Louis, St. Louis, MO, USA., Barch DM; Mallinckrodt Institute of Radiology, Washington University School of Medicine, St. Louis, MO, USA; Department of Psychiatry, Washington University School of Medicine, St. Louis, MO, USA; Department of Psychological and Brain Sciences, Washington University in St. Louis, St. Louis, MO, USA., Fair DA; Masonic Institute for the Developing Brain, University of Minnesota Medical School, Minneapolis, MN, USA; Department of Pediatrics, University of Minnesota, Minneapolis, MN, USA; Institute of Child Development, University of Minnesota, Minneapolis, MN, USA., Dosenbach NUF; Department of Neurology, Washington University School of Medicine, St. Louis, MO, USA; Allied Labs for Imaging Guided Neurotherapies (ALIGN), Washington University School of Medicine, St. Louis, MO, USA; Mallinckrodt Institute of Radiology, Washington University School of Medicine, St. Louis, MO, USA; Department of Biomedical Engineering, Washington University in St. Louis, St. Louis, MO, USA; Department of Psychological and Brain Sciences, Washington University in St. Louis, St. Louis, MO, USA; Program in Occupational Therapy, Washington University in St. Louis, St. Louis, MO, USA; Department of Pediatrics, Washington University School of Medicine, St. Louis, MO, USA.
Source: Cell [Cell] 2025 Dec 24; Vol. 188 (26), pp. 7529-7546.e20.
Publication Type: Journal Article
Journal Info: Publisher: Cell Press Country of Publication: United States NLM ID: 0413066 Publication Model: Print Cited Medium: Internet ISSN: 1097-4172 (Electronic) Linking ISSN: 00928674 NLM ISO Abbreviation: Cell Subsets: MEDLINE
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  Data: Stimulant medications affect arousal and reward, not attention networks.
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Electronic address: benjamin.kay@wustl.edu.<br /><searchLink fieldCode="AU" term="%22Wheelock+MD%22">Wheelock MD</searchLink>; Mallinckrodt Institute of Radiology, Washington University School of Medicine, St. Louis, MO, USA.<br /><searchLink fieldCode="AU" term="%22Siegel+JS%22">Siegel JS</searchLink>; Department of Psychiatry, New York University Langone Center for Psychedelic Medicine, New York, NY, USA.<br /><searchLink fieldCode="AU" term="%22Raut+RV%22">Raut RV</searchLink>; Mallinckrodt Institute of Radiology, Washington University School of Medicine, St. Louis, MO, USA; Allen Institute, Seattle, WA, USA; Department of Physiology & Biophysics, University of Washington, Seattle, WA, USA.<br /><searchLink fieldCode="AU" term="%22Chauvin+RJ%22">Chauvin RJ</searchLink>; Department of Neurology, Washington University School of Medicine, St. Louis, MO, USA; Allied Labs for Imaging Guided Neurotherapies (ALIGN), Washington University School of Medicine, St. Louis, MO, USA.<br /><searchLink fieldCode="AU" term="%22Metoki+A%22">Metoki A</searchLink>; 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Department of Neurology, Washington University School of Medicine, St. Louis, MO, USA; Allied Labs for Imaging Guided Neurotherapies (ALIGN), Washington University School of Medicine, St. Louis, MO, USA.<br /><searchLink fieldCode="AU" term="%22Monk+JS%22">Monk JS</searchLink>; Department of Neurology, Washington University School of Medicine, St. Louis, MO, USA; Allied Labs for Imaging Guided Neurotherapies (ALIGN), Washington University School of Medicine, St. Louis, MO, USA.<br /><searchLink fieldCode="AU" term="%22Whiting+FI%22">Whiting FI</searchLink>; Department of Neurology, Washington University School of Medicine, St. Louis, MO, USA; Allied Labs for Imaging Guided Neurotherapies (ALIGN), Washington University School of Medicine, St. Louis, MO, USA.<br /><searchLink fieldCode="AU" term="%22Ramirez-Perez+N%22">Ramirez-Perez N</searchLink>; Department of Neurology, Washington University School of Medicine, St. Louis, MO, USA; Allied Labs for Imaging Guided Neurotherapies (ALIGN), Washington University School of Medicine, St. Louis, MO, USA; 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Taylor Family Department of Neurosurgery, Washington University School of Medicine, St Louis, MO, USA.<br /><searchLink fieldCode="AU" term="%22Nicol+GE%22">Nicol GE</searchLink>; Allied Labs for Imaging Guided Neurotherapies (ALIGN), Washington University School of Medicine, St. Louis, MO, USA; Department of Psychiatry, Washington University School of Medicine, St. Louis, MO, USA.<br /><searchLink fieldCode="AU" term="%22Laumann+TO%22">Laumann TO</searchLink>; Allied Labs for Imaging Guided Neurotherapies (ALIGN), Washington University School of Medicine, St. Louis, MO, USA; Mallinckrodt Institute of Radiology, Washington University School of Medicine, St. Louis, MO, USA; Department of Psychiatry, Washington University School of Medicine, St. Louis, MO, USA.<br /><searchLink fieldCode="AU" term="%22Marek+S%22">Marek S</searchLink>; Allied Labs for Imaging Guided Neurotherapies (ALIGN), Washington University School of Medicine, St. Louis, MO, USA; Mallinckrodt Institute of Radiology, Washington University School of Medicine, St. Louis, MO, USA.<br /><searchLink fieldCode="AU" term="%22Gordon+EM%22">Gordon EM</searchLink>; 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