Trastuzumab Deruxtecan in Patients With HER2-Overexpressing NSCLC: Results From Part 1 of the Open-Label, Multicenter, Phase 1b DESTINY-Lung03 Trial.
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| Title: | Trastuzumab Deruxtecan in Patients With HER2-Overexpressing NSCLC: Results From Part 1 of the Open-Label, Multicenter, Phase 1b DESTINY-Lung03 Trial. |
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| Authors: | Planchard D; Department of Medical Oncology, Thoracic Group, Gustave Roussy, Villejuif, France; Faculty of Medicine, Paris-Saclay University, Paris, France. Electronic address: David.PLANCHARD@gustaveroussy.fr., Kim HR; Division of Medical Oncology, Yonsei Cancer Center, Seoul, Republic of Korea., Suksombooncharoen T; Department of Internal Medicine, Faculty of Medicine, Chiang Mai University, Chiang Mai, Thailand., Li R; Section of Medical Oncology, St Luke's Medical Center, Metro Manila, Philippines., Cortinovis D; Division of Medical Oncology, Fondazione IRCCS San Gerardo dei Tintori Monza, Monza, Italy; Department of Medicine, University of Milano-Bicocca, Milan, Italy., Han JY; Center for Lung Cancer, National Cancer Center, Goyang-si Gyeonggi-do, Republic of Korea., Samol J; Department of Medical Oncology, Tan Tock Seng Hospital, Singapore; Johns Hopkins University, Baltimore, Maryland; Lee Kong Chian School of Medicine/Nanyang Technological University, Singapore., Runglodvatana Y; Department of Medicine, Faculty of Medicine Vajira Hospital, Bangkok, Thailand., Lee KY; Department of Internal Medicine, Shuang Ho Hospital, Taipei Medical University, New Taipei City, Taiwan., Chang GC; School of Medicine, Chung Shan Medical University, Taichung City, Taiwan; Institute of Medicine, Chung Shan Medical University, Taichung City, Taiwan; Division of Pulmonary Medicine, Department of Internal Medicine, Chung Shan Medical University Hospital, Taichung City, Taiwan., Lee CH; Department of Oncology, National Cheng Kung University Hospital, Tainan, Taiwan., Kowalski D; Department of Lung and Chest Cancer, Maria Sklodowska-Curie National Research Institute of Oncology, Warsaw, Poland., Saw SPL; Division of Medical Oncology, National Cancer Center Singapore, Singapore; Duke-National University of Singapore Medical School, Singapore., Huang Y; Department of Hematology-Oncology, National University Cancer Institute, Singapore., Ruiter G; Department of Clinical Pharmacology and Thoracic Oncology, The Netherlands Cancer Institute-Antoni Van Leeuwenhoek Hospital, Amsterdam, The Netherlands., Ahn MJ; Department of Hematology-Oncology, Samsung Medical Center, Sungkyunkwan University, Seoul, Republic of Korea., Yang TY; Department of Chest Medicine, Taichung Veterans General Hospital, Taichung City, Taiwan; Doctoral Program in Translational Medicine, National Chung Hsing University, Taichung City, Taiwan., Yang CT; Chang Gung Memorial Hospital, Taoyuan, Taiwan., Sookprasert A; Medical Oncology Unit, Department of Medicine, Faculty of Medicine, Khon Kaen University, Muang District, Thailand., Nakajima EC; Clinical Development, Late-Stage Development, Oncology R&D, AstraZeneca, Gaithersburg, Maryland., Alfon J; Clinical Development, Late-Stage Development, Oncology R&D, AstraZeneca, Barcelona, Spain., McEwen R; Oncology Data Science, Research and Early Development, Oncology R&D, AstraZeneca, Cambridge, United Kingdom., Chang YT; Oncology Biometrics, Late-Stage Development, Oncology R&D, AstraZeneca, Gaithersburg, Maryland., Yang JC; Department of Oncology, National Taiwan University Hospital and National Taiwan University Cancer Center, Taipei City, Taiwan. |
| Source: | Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer [J Thorac Oncol] 2026 May; Vol. 21 (5), pp. 103541. Date of Electronic Publication: 2025 Dec 23. |
| Publication Type: | Journal Article; Clinical Trial, Phase I; Multicenter Study |
| Journal Info: | Publisher: Elsevier Country of Publication: United States NLM ID: 101274235 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1556-1380 (Electronic) Linking ISSN: 15560864 NLM ISO Abbreviation: J Thorac Oncol Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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