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Global loss of selenocysteine lyase in mice drives lipid accumulation in brown adipocytes.

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Title: Global loss of selenocysteine lyase in mice drives lipid accumulation in brown adipocytes.
Authors: Shimada BK; Pacific Biosciences Research Center, School of Ocean and Earth Science and Technology, University of Hawaii at Manoa, Honolulu, Hawaii, United States., Ogawa-Wong AN; Department of Cell and Molecular Biology, John A. Burns School of Medicine, University of Hawaii at Manoa, Honolulu, Hawaii, United States.; Division of Endocrinology, Diabetes and Metabolism, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts, United States., Soares AG; Pacific Biosciences Research Center, School of Ocean and Earth Science and Technology, University of Hawaii at Manoa, Honolulu, Hawaii, United States., Hallam KA; Pacific Biosciences Research Center, School of Ocean and Earth Science and Technology, University of Hawaii at Manoa, Honolulu, Hawaii, United States., Santiago PJD; Pacific Biosciences Research Center, School of Ocean and Earth Science and Technology, University of Hawaii at Manoa, Honolulu, Hawaii, United States., Saelua K; Pacific Biosciences Research Center, School of Ocean and Earth Science and Technology, University of Hawaii at Manoa, Honolulu, Hawaii, United States., Nakahara-Akita KK; Pacific Biosciences Research Center, School of Ocean and Earth Science and Technology, University of Hawaii at Manoa, Honolulu, Hawaii, United States., Torres DJ; Pacific Biosciences Research Center, School of Ocean and Earth Science and Technology, University of Hawaii at Manoa, Honolulu, Hawaii, United States., Brockman JD; Missouri University Research Reactor, University of Missouri-Columbia, Columbia, Missouri, United States., Kurokawa S; Department of Cell and Molecular Biology, John A. Burns School of Medicine, University of Hawaii at Manoa, Honolulu, Hawaii, United States., Ewell KL; Department of Cell and Molecular Biology, John A. Burns School of Medicine, University of Hawaii at Manoa, Honolulu, Hawaii, United States., Bellinger MT; Department of Cell and Molecular Biology, John A. Burns School of Medicine, University of Hawaii at Manoa, Honolulu, Hawaii, United States., Toh P; Pacific Biosciences Research Center, School of Ocean and Earth Science and Technology, University of Hawaii at Manoa, Honolulu, Hawaii, United States., Lagatta Pamplona Remedios G; Pacific Biosciences Research Center, School of Ocean and Earth Science and Technology, University of Hawaii at Manoa, Honolulu, Hawaii, United States., Alfulaij N; Pacific Biosciences Research Center, School of Ocean and Earth Science and Technology, University of Hawaii at Manoa, Honolulu, Hawaii, United States., Swanson SM; Pacific Biosciences Research Center, School of Ocean and Earth Science and Technology, University of Hawaii at Manoa, Honolulu, Hawaii, United States., Seyedali A; Department of Cell and Molecular Biology, John A. Burns School of Medicine, University of Hawaii at Manoa, Honolulu, Hawaii, United States., Zavacki AM; Division of Endocrinology, Diabetes and Metabolism, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts, United States., Berry MJ; Pacific Biosciences Research Center, School of Ocean and Earth Science and Technology, University of Hawaii at Manoa, Honolulu, Hawaii, United States., Seale LA; Pacific Biosciences Research Center, School of Ocean and Earth Science and Technology, University of Hawaii at Manoa, Honolulu, Hawaii, United States.
Source: American journal of physiology. Endocrinology and metabolism [Am J Physiol Endocrinol Metab] 2026 Feb 01; Vol. 330 (2), pp. E000. Date of Electronic Publication: 2025 Dec 26.
Publication Type: Journal Article
Journal Info: Publisher: American Physiological Society Country of Publication: United States NLM ID: 100901226 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1522-1555 (Electronic) Linking ISSN: 01931849 NLM ISO Abbreviation: Am J Physiol Endocrinol Metab Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Global loss of selenocysteine lyase in mice drives lipid accumulation in brown adipocytes.
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  Data: <searchLink fieldCode="AU" term="%22Shimada+BK%22">Shimada BK</searchLink>; Pacific Biosciences Research Center, School of Ocean and Earth Science and Technology, University of Hawaii at Manoa, Honolulu, Hawaii, United States.<br /><searchLink fieldCode="AU" term="%22Ogawa-Wong+AN%22">Ogawa-Wong AN</searchLink>; Department of Cell and Molecular Biology, John A. Burns School of Medicine, University of Hawaii at Manoa, Honolulu, Hawaii, United States.; Division of Endocrinology, Diabetes and Metabolism, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts, United States.<br /><searchLink fieldCode="AU" term="%22Soares+AG%22">Soares AG</searchLink>; Pacific Biosciences Research Center, School of Ocean and Earth Science and Technology, University of Hawaii at Manoa, Honolulu, Hawaii, United States.<br /><searchLink fieldCode="AU" term="%22Hallam+KA%22">Hallam KA</searchLink>; Pacific Biosciences Research Center, School of Ocean and Earth Science and Technology, University of Hawaii at Manoa, Honolulu, Hawaii, United States.<br /><searchLink fieldCode="AU" term="%22Santiago+PJD%22">Santiago PJD</searchLink>; Pacific Biosciences Research Center, School of Ocean and Earth Science and Technology, University of Hawaii at Manoa, Honolulu, Hawaii, United States.<br /><searchLink fieldCode="AU" term="%22Saelua+K%22">Saelua K</searchLink>; Pacific Biosciences Research Center, School of Ocean and Earth Science and Technology, University of Hawaii at Manoa, Honolulu, Hawaii, United States.<br /><searchLink fieldCode="AU" term="%22Nakahara-Akita+KK%22">Nakahara-Akita KK</searchLink>; Pacific Biosciences Research Center, School of Ocean and Earth Science and Technology, University of Hawaii at Manoa, Honolulu, Hawaii, United States.<br /><searchLink fieldCode="AU" term="%22Torres+DJ%22">Torres DJ</searchLink>; Pacific Biosciences Research Center, School of Ocean and Earth Science and Technology, University of Hawaii at Manoa, Honolulu, Hawaii, United States.<br /><searchLink fieldCode="AU" term="%22Brockman+JD%22">Brockman JD</searchLink>; Missouri University Research Reactor, University of Missouri-Columbia, Columbia, Missouri, United States.<br /><searchLink fieldCode="AU" term="%22Kurokawa+S%22">Kurokawa S</searchLink>; Department of Cell and Molecular Biology, John A. Burns School of Medicine, University of Hawaii at Manoa, Honolulu, Hawaii, United States.<br /><searchLink fieldCode="AU" term="%22Ewell+KL%22">Ewell KL</searchLink>; Department of Cell and Molecular Biology, John A. Burns School of Medicine, University of Hawaii at Manoa, Honolulu, Hawaii, United States.<br /><searchLink fieldCode="AU" term="%22Bellinger+MT%22">Bellinger MT</searchLink>; Department of Cell and Molecular Biology, John A. Burns School of Medicine, University of Hawaii at Manoa, Honolulu, Hawaii, United States.<br /><searchLink fieldCode="AU" term="%22Toh+P%22">Toh P</searchLink>; Pacific Biosciences Research Center, School of Ocean and Earth Science and Technology, University of Hawaii at Manoa, Honolulu, Hawaii, United States.<br /><searchLink fieldCode="AU" term="%22Lagatta+Pamplona+Remedios+G%22">Lagatta Pamplona Remedios G</searchLink>; Pacific Biosciences Research Center, School of Ocean and Earth Science and Technology, University of Hawaii at Manoa, Honolulu, Hawaii, United States.<br /><searchLink fieldCode="AU" term="%22Alfulaij+N%22">Alfulaij N</searchLink>; Pacific Biosciences Research Center, School of Ocean and Earth Science and Technology, University of Hawaii at Manoa, Honolulu, Hawaii, United States.<br /><searchLink fieldCode="AU" term="%22Swanson+SM%22">Swanson SM</searchLink>; Pacific Biosciences Research Center, School of Ocean and Earth Science and Technology, University of Hawaii at Manoa, Honolulu, Hawaii, United States.<br /><searchLink fieldCode="AU" term="%22Seyedali+A%22">Seyedali A</searchLink>; Department of Cell and Molecular Biology, John A. Burns School of Medicine, University of Hawaii at Manoa, Honolulu, Hawaii, United States.<br /><searchLink fieldCode="AU" term="%22Zavacki+AM%22">Zavacki AM</searchLink>; Division of Endocrinology, Diabetes and Metabolism, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts, United States.<br /><searchLink fieldCode="AU" term="%22Berry+MJ%22">Berry MJ</searchLink>; Pacific Biosciences Research Center, School of Ocean and Earth Science and Technology, University of Hawaii at Manoa, Honolulu, Hawaii, United States.<br /><searchLink fieldCode="AU" term="%22Seale+LA%22">Seale LA</searchLink>; Pacific Biosciences Research Center, School of Ocean and Earth Science and Technology, University of Hawaii at Manoa, Honolulu, Hawaii, United States.
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  Data: <searchLink fieldCode="JN" term="%22100901226%22">American journal of physiology. Endocrinology and metabolism</searchLink> [Am J Physiol Endocrinol Metab] 2026 Feb 01; Vol. 330 (2), pp. E000. <i>Date of Electronic Publication: </i>2025 Dec 26.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22American+Physiological+Society%22">American Physiological Society </searchLink><i>Country of Publication: </i>United States <i>NLM ID: </i>100901226 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1522-1555 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2201931849%22">01931849 </searchLink><i>NLM ISO Abbreviation: </i>Am J Physiol Endocrinol Metab <i>Subsets: </i>MEDLINE
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        Value: 10.1152/ajpendo.00213.2025
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