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The therapeutic readiness of probiotics in major depressive disorder: A systematic review of randomised controlled trials.

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Title: The therapeutic readiness of probiotics in major depressive disorder: A systematic review of randomised controlled trials.
Authors: Johnson D; Novel Bacteria and Drug Discovery Research Group (NBDD), Microbiome and Bioresource Research Strength (MBRS), Jeffrey Cheah School of Medicine and Health Sciences, Monash University Malaysia, Bandar Sunway, Malaysia.; Pathogen Resistome Virulome and Diagnostic Research Group (PathRiD), Jeffrey Cheah School of Medicine and Health Sciences, Monash University Malaysia, Bandar Sunway, Malaysia., Ramachandram DS; School of Pharmacy, Monash University Malaysia, Bandar Sunway, Malaysia., Doorly J; UCD Intern Network, University College Dublin, Ireland., Clarke G; Department of Psychiatry and Neurobehavioural Science and APC Microbiome Ireland, University College Cork, Ireland., Chan KG; Novel Bacteria and Drug Discovery Research Group (NBDD), Microbiome and Bioresource Research Strength (MBRS), Jeffrey Cheah School of Medicine and Health Sciences, Monash University Malaysia, Bandar Sunway, Malaysia.; Division of Genetics and Molecular Biology, Institute of Biological Sciences, Faculty of Science, University of Malaya, Kuala Lumpur, Malaysia., Thurairajasingam S; Clinical School Johor Bahru, Jeffrey Cheah School of Medicine and Health Sciences, Monash University Malaysia, Malaysia., Lee LH; Novel Bacteria and Drug Discovery Research Group (NBDD), Microbiome and Bioresource Research Strength (MBRS), Jeffrey Cheah School of Medicine and Health Sciences, Monash University Malaysia, Bandar Sunway, Malaysia.; Microbiome Research Group, Research Centre for Life Science and Healthcare, Nottingham Ningbo China Beacons of Excellence Research and Innovation Institute (CBI), University of Nottingham Ningbo China, China., Letchumanan V; Novel Bacteria and Drug Discovery Research Group (NBDD), Microbiome and Bioresource Research Strength (MBRS), Jeffrey Cheah School of Medicine and Health Sciences, Monash University Malaysia, Bandar Sunway, Malaysia.; Pathogen Resistome Virulome and Diagnostic Research Group (PathRiD), Jeffrey Cheah School of Medicine and Health Sciences, Monash University Malaysia, Bandar Sunway, Malaysia.
Source: Journal of psychopharmacology (Oxford, England) [J Psychopharmacol] 2026 Apr; Vol. 40 (4), pp. 530-543. Date of Electronic Publication: 2025 Dec 26.
Publication Type: Systematic Review; Journal Article; Review
Journal Info: Publisher: Sage Publications Country of Publication: United States NLM ID: 8907828 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1461-7285 (Electronic) Linking ISSN: 02698811 NLM ISO Abbreviation: J Psychopharmacol Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: The therapeutic readiness of probiotics in major depressive disorder: A systematic review of randomised controlled trials.
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  Data: <searchLink fieldCode="AU" term="%22Johnson+D%22">Johnson D</searchLink>; Novel Bacteria and Drug Discovery Research Group (NBDD), Microbiome and Bioresource Research Strength (MBRS), Jeffrey Cheah School of Medicine and Health Sciences, Monash University Malaysia, Bandar Sunway, Malaysia.; Pathogen Resistome Virulome and Diagnostic Research Group (PathRiD), Jeffrey Cheah School of Medicine and Health Sciences, Monash University Malaysia, Bandar Sunway, Malaysia.<br /><searchLink fieldCode="AU" term="%22Ramachandram+DS%22">Ramachandram DS</searchLink>; School of Pharmacy, Monash University Malaysia, Bandar Sunway, Malaysia.<br /><searchLink fieldCode="AU" term="%22Doorly+J%22">Doorly J</searchLink>; UCD Intern Network, University College Dublin, Ireland.<br /><searchLink fieldCode="AU" term="%22Clarke+G%22">Clarke G</searchLink>; Department of Psychiatry and Neurobehavioural Science and APC Microbiome Ireland, University College Cork, Ireland.<br /><searchLink fieldCode="AU" term="%22Chan+KG%22">Chan KG</searchLink>; Novel Bacteria and Drug Discovery Research Group (NBDD), Microbiome and Bioresource Research Strength (MBRS), Jeffrey Cheah School of Medicine and Health Sciences, Monash University Malaysia, Bandar Sunway, Malaysia.; Division of Genetics and Molecular Biology, Institute of Biological Sciences, Faculty of Science, University of Malaya, Kuala Lumpur, Malaysia.<br /><searchLink fieldCode="AU" term="%22Thurairajasingam+S%22">Thurairajasingam S</searchLink>; Clinical School Johor Bahru, Jeffrey Cheah School of Medicine and Health Sciences, Monash University Malaysia, Malaysia.<br /><searchLink fieldCode="AU" term="%22Lee+LH%22">Lee LH</searchLink>; Novel Bacteria and Drug Discovery Research Group (NBDD), Microbiome and Bioresource Research Strength (MBRS), Jeffrey Cheah School of Medicine and Health Sciences, Monash University Malaysia, Bandar Sunway, Malaysia.; Microbiome Research Group, Research Centre for Life Science and Healthcare, Nottingham Ningbo China Beacons of Excellence Research and Innovation Institute (CBI), University of Nottingham Ningbo China, China.<br /><searchLink fieldCode="AU" term="%22Letchumanan+V%22">Letchumanan V</searchLink>; Novel Bacteria and Drug Discovery Research Group (NBDD), Microbiome and Bioresource Research Strength (MBRS), Jeffrey Cheah School of Medicine and Health Sciences, Monash University Malaysia, Bandar Sunway, Malaysia.; Pathogen Resistome Virulome and Diagnostic Research Group (PathRiD), Jeffrey Cheah School of Medicine and Health Sciences, Monash University Malaysia, Bandar Sunway, Malaysia.
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  Data: <searchLink fieldCode="JN" term="%228907828%22">Journal of psychopharmacology (Oxford, England)</searchLink> [J Psychopharmacol] 2026 Apr; Vol. 40 (4), pp. 530-543. <i>Date of Electronic Publication: </i>2025 Dec 26.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Sage+Publications%22">Sage Publications </searchLink><i>Country of Publication: </i>United States <i>NLM ID: </i>8907828 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1461-7285 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2202698811%22">02698811 </searchLink><i>NLM ISO Abbreviation: </i>J Psychopharmacol <i>Subsets: </i>MEDLINE
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        Value: 10.1177/02698811251397332
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              Text: 2026 Apr
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              Y: 2026
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