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Ebola virus matrix protein VP40 triggers inflammatory responses linked to the ebolavirus virulence.

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Title: Ebola virus matrix protein VP40 triggers inflammatory responses linked to the ebolavirus virulence.
Authors: Yamaoka S; Department of Medicine, Division of Infectious Diseases, Mayo Clinic, Rochester, MN 55905., M'Hamdi Z; Vaccine and Infectious Disease Organization, University of Saskatchewan, Saskatoon, SK S7N 5E3, Canada., Wang L; Department of Medicine, Division of Infectious Diseases, Mayo Clinic, Rochester, MN 55905., Swenson VA; Virology and Gene Therapy Track, Mayo Graduate School of Biomedical Sciences, Rochester, MN 55905., McNally KL; Laboratory of Virology, Rocky Mountain Laboratories, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Hamilton, MT 59840., Lu SC; Department of Medicine, Division of Infectious Diseases, Mayo Clinic, Rochester, MN 55905., Singh R; Vaccine and Infectious Disease Organization, University of Saskatchewan, Saskatoon, SK S7N 5E3, Canada., Saundh SL; Vaccine and Infectious Disease Organization, University of Saskatchewan, Saskatoon, SK S7N 5E3, Canada., Zell BN; Virology and Gene Therapy Track, Mayo Graduate School of Biomedical Sciences, Rochester, MN 55905., Best SM; Laboratory of Virology, Rocky Mountain Laboratories, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Hamilton, MT 59840.; Laboratory of Neurological Infections and Immunity, Rocky Mountain Laboratories, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Hamilton, MT 59840., Barry MA; Department of Medicine, Division of Infectious Diseases, Mayo Clinic, Rochester, MN 55905.; Department of Immunology, Mayo Clinic, Rochester, MN 55905., Rasmussen AL; Vaccine and Infectious Disease Organization, University of Saskatchewan, Saskatoon, SK S7N 5E3, Canada.; Department of Biochemistry, Microbiology, and Immunology, University of Saskatchewan, Saskatoon, SK S7N 5E3, Canada.; Department of Ecology and Evolution, Stony Brook University, Stony Brook, NY 11794., Ebihara H; Department of Virology 1, National Institute of Infectious Diseases, Japan Institute for Health Security, Tokyo 162-8640, Japan.
Source: Proceedings of the National Academy of Sciences of the United States of America [Proc Natl Acad Sci U S A] 2026 Jan 06; Vol. 123 (1), pp. e2508194123. Date of Electronic Publication: 2025 Dec 29.
Publication Type: Journal Article
Journal Info: Publisher: National Academy of Sciences Country of Publication: United States NLM ID: 7505876 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1091-6490 (Electronic) Linking ISSN: 00278424 NLM ISO Abbreviation: Proc Natl Acad Sci U S A Subsets: MEDLINE
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  Data: Ebola virus matrix protein VP40 triggers inflammatory responses linked to the ebolavirus virulence.
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  Data: <searchLink fieldCode="AU" term="%22Yamaoka+S%22">Yamaoka S</searchLink>; Department of Medicine, Division of Infectious Diseases, Mayo Clinic, Rochester, MN 55905.<br /><searchLink fieldCode="AU" term="%22M'Hamdi+Z%22">M'Hamdi Z</searchLink>; Vaccine and Infectious Disease Organization, University of Saskatchewan, Saskatoon, SK S7N 5E3, Canada.<br /><searchLink fieldCode="AU" term="%22Wang+L%22">Wang L</searchLink>; Department of Medicine, Division of Infectious Diseases, Mayo Clinic, Rochester, MN 55905.<br /><searchLink fieldCode="AU" term="%22Swenson+VA%22">Swenson VA</searchLink>; Virology and Gene Therapy Track, Mayo Graduate School of Biomedical Sciences, Rochester, MN 55905.<br /><searchLink fieldCode="AU" term="%22McNally+KL%22">McNally KL</searchLink>; Laboratory of Virology, Rocky Mountain Laboratories, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Hamilton, MT 59840.<br /><searchLink fieldCode="AU" term="%22Lu+SC%22">Lu SC</searchLink>; Department of Medicine, Division of Infectious Diseases, Mayo Clinic, Rochester, MN 55905.<br /><searchLink fieldCode="AU" term="%22Singh+R%22">Singh R</searchLink>; Vaccine and Infectious Disease Organization, University of Saskatchewan, Saskatoon, SK S7N 5E3, Canada.<br /><searchLink fieldCode="AU" term="%22Saundh+SL%22">Saundh SL</searchLink>; Vaccine and Infectious Disease Organization, University of Saskatchewan, Saskatoon, SK S7N 5E3, Canada.<br /><searchLink fieldCode="AU" term="%22Zell+BN%22">Zell BN</searchLink>; Virology and Gene Therapy Track, Mayo Graduate School of Biomedical Sciences, Rochester, MN 55905.<br /><searchLink fieldCode="AU" term="%22Best+SM%22">Best SM</searchLink>; Laboratory of Virology, Rocky Mountain Laboratories, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Hamilton, MT 59840.; Laboratory of Neurological Infections and Immunity, Rocky Mountain Laboratories, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Hamilton, MT 59840.<br /><searchLink fieldCode="AU" term="%22Barry+MA%22">Barry MA</searchLink>; Department of Medicine, Division of Infectious Diseases, Mayo Clinic, Rochester, MN 55905.; Department of Immunology, Mayo Clinic, Rochester, MN 55905.<br /><searchLink fieldCode="AU" term="%22Rasmussen+AL%22">Rasmussen AL</searchLink>; Vaccine and Infectious Disease Organization, University of Saskatchewan, Saskatoon, SK S7N 5E3, Canada.; Department of Biochemistry, Microbiology, and Immunology, University of Saskatchewan, Saskatoon, SK S7N 5E3, Canada.; Department of Ecology and Evolution, Stony Brook University, Stony Brook, NY 11794.<br /><searchLink fieldCode="AU" term="%22Ebihara+H%22">Ebihara H</searchLink>; Department of Virology 1, National Institute of Infectious Diseases, Japan Institute for Health Security, Tokyo 162-8640, Japan.
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  Data: <searchLink fieldCode="JN" term="%227505876%22">Proceedings of the National Academy of Sciences of the United States of America</searchLink> [Proc Natl Acad Sci U S A] 2026 Jan 06; Vol. 123 (1), pp. e2508194123. <i>Date of Electronic Publication: </i>2025 Dec 29.
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