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Eosinophils and the Efficacy of Immune Checkpoint Inhibitors Across Multiple Cancers: A Retrospective Study.

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Title: Eosinophils and the Efficacy of Immune Checkpoint Inhibitors Across Multiple Cancers: A Retrospective Study.
Authors: Suzuki R; Department of Medical Oncology, Department of Medicine, School of Medicine, Showa Medical University, Tokyo 142-8666, Japan.; Department of Clinical Diagnostic Oncology, Clinical Research Institute for Clinical Pharmacology and Therapeutics, Showa Medical University, Tokyo 157-8577, Japan.; Department of Pharmacology, Showa Medical University Graduate School of Medicine, Tokyo 142-8555, Japan., Ohkuma R; Department of Medical Oncology, Department of Medicine, School of Medicine, Showa Medical University, Tokyo 142-8666, Japan.; Department of Clinical Diagnostic Oncology, Clinical Research Institute for Clinical Pharmacology and Therapeutics, Showa Medical University, Tokyo 157-8577, Japan.; Comprehensive Cancer Information Center, Showa Medical University, Tokyo 142-8555, Japan., Watanabe M; Department of Clinical Diagnostic Oncology, Clinical Research Institute for Clinical Pharmacology and Therapeutics, Showa Medical University, Tokyo 157-8577, Japan.; Department of Pharmacology, Showa Medical University Graduate School of Medicine, Tokyo 142-8555, Japan.; Pharmacological Research Center, Showa Medical University, Tokyo 142-8555, Japan.; Clinical Research Institute for Clinical Pharmacology and Therapeutics, Showa Medical University, Tokyo 157-8577, Japan., Mura E; Department of Medical Oncology, Department of Medicine, School of Medicine, Showa Medical University, Tokyo 142-8666, Japan., Tsurui T; Department of Medical Oncology, Department of Medicine, School of Medicine, Showa Medical University, Tokyo 142-8666, Japan., Iriguchi N; Department of Medical Oncology, Department of Medicine, School of Medicine, Showa Medical University, Tokyo 142-8666, Japan., Ishiguro T; Department of Medical Oncology, Department of Medicine, School of Medicine, Showa Medical University, Tokyo 142-8666, Japan., Hirasawa Y; Department of Medical Oncology, Department of Medicine, School of Medicine, Showa Medical University, Tokyo 142-8666, Japan., Ikeda G; Department of Medical Oncology, Department of Medicine, School of Medicine, Showa Medical University, Tokyo 142-8666, Japan., Shimokawa M; Department of Medical Oncology, Department of Medicine, School of Medicine, Showa Medical University, Tokyo 142-8666, Japan., Ariizumi H; Department of Medical Oncology, Department of Medicine, School of Medicine, Showa Medical University, Tokyo 142-8666, Japan., Kubota Y; Department of Medical Oncology, Department of Medicine, School of Medicine, Showa Medical University, Tokyo 142-8666, Japan., Yoshimura K; Department of Medical Oncology, Department of Medicine, School of Medicine, Showa Medical University, Tokyo 142-8666, Japan.; Clinical Research Institute for Clinical Pharmacology and Therapeutics, Showa Medical University, Tokyo 157-8577, Japan.; Department of Clinical Immuno Oncology, Clinical Research Institute for Clinical Pharmacology and Therapeutics, Showa Medical University, Tokyo 157-8577, Japan., Kobayashi S; Clinical Research Institute for Clinical Pharmacology and Therapeutics, Showa Medical University, Tokyo 157-8577, Japan., Tsunoda T; Department of Medical Oncology, Department of Medicine, School of Medicine, Showa Medical University, Tokyo 142-8666, Japan.; Comprehensive Cancer Information Center, Showa Medical University, Tokyo 142-8555, Japan., Horiike A; Department of Medical Oncology, Department of Medicine, School of Medicine, Showa Medical University, Tokyo 142-8666, Japan., Tsuji M; Pharmacological Research Center, Showa Medical University, Tokyo 142-8555, Japan., Kiuchi Y; Department of Pharmacology, Showa Medical University Graduate School of Medicine, Tokyo 142-8555, Japan.; Pharmacological Research Center, Showa Medical University, Tokyo 142-8555, Japan., Oguchi T; Department of Pharmacology, Showa Medical University Graduate School of Medicine, Tokyo 142-8555, Japan.; Pharmacological Research Center, Showa Medical University, Tokyo 142-8555, Japan., Wada S; Department of Medical Oncology, Department of Medicine, School of Medicine, Showa Medical University, Tokyo 142-8666, Japan.; Department of Clinical Diagnostic Oncology, Clinical Research Institute for Clinical Pharmacology and Therapeutics, Showa Medical University, Tokyo 157-8577, Japan.; Department of Pharmacology, Showa Medical University Graduate School of Medicine, Tokyo 142-8555, Japan.; Clinical Research Institute for Clinical Pharmacology and Therapeutics, Showa Medical University, Tokyo 157-8577, Japan.
Source: Biomedicines [Biomedicines] 2025 Dec 10; Vol. 13 (12). Date of Electronic Publication: 2025 Dec 10.
Publication Type: Journal Article
Journal Info: Publisher: MDPI AG Country of Publication: Switzerland NLM ID: 101691304 Publication Model: Electronic Cited Medium: Print ISSN: 2227-9059 (Print) Linking ISSN: 22279059 NLM ISO Abbreviation: Biomedicines Subsets: PubMed not MEDLINE
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  Data: Eosinophils and the Efficacy of Immune Checkpoint Inhibitors Across Multiple Cancers: A Retrospective Study.
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  Data: <searchLink fieldCode="AU" term="%22Suzuki+R%22">Suzuki R</searchLink>; Department of Medical Oncology, Department of Medicine, School of Medicine, Showa Medical University, Tokyo 142-8666, Japan.; Department of Clinical Diagnostic Oncology, Clinical Research Institute for Clinical Pharmacology and Therapeutics, Showa Medical University, Tokyo 157-8577, Japan.; Department of Pharmacology, Showa Medical University Graduate School of Medicine, Tokyo 142-8555, Japan.<br /><searchLink fieldCode="AU" term="%22Ohkuma+R%22">Ohkuma R</searchLink>; Department of Medical Oncology, Department of Medicine, School of Medicine, Showa Medical University, Tokyo 142-8666, Japan.; Department of Clinical Diagnostic Oncology, Clinical Research Institute for Clinical Pharmacology and Therapeutics, Showa Medical University, Tokyo 157-8577, Japan.; Comprehensive Cancer Information Center, Showa Medical University, Tokyo 142-8555, Japan.<br /><searchLink fieldCode="AU" term="%22Watanabe+M%22">Watanabe M</searchLink>; Department of Clinical Diagnostic Oncology, Clinical Research Institute for Clinical Pharmacology and Therapeutics, Showa Medical University, Tokyo 157-8577, Japan.; Department of Pharmacology, Showa Medical University Graduate School of Medicine, Tokyo 142-8555, Japan.; Pharmacological Research Center, Showa Medical University, Tokyo 142-8555, Japan.; Clinical Research Institute for Clinical Pharmacology and Therapeutics, Showa Medical University, Tokyo 157-8577, Japan.<br /><searchLink fieldCode="AU" term="%22Mura+E%22">Mura E</searchLink>; Department of Medical Oncology, Department of Medicine, School of Medicine, Showa Medical University, Tokyo 142-8666, Japan.<br /><searchLink fieldCode="AU" term="%22Tsurui+T%22">Tsurui T</searchLink>; Department of Medical Oncology, Department of Medicine, School of Medicine, Showa Medical University, Tokyo 142-8666, Japan.<br /><searchLink fieldCode="AU" term="%22Iriguchi+N%22">Iriguchi N</searchLink>; Department of Medical Oncology, Department of Medicine, School of Medicine, Showa Medical University, Tokyo 142-8666, Japan.<br /><searchLink fieldCode="AU" term="%22Ishiguro+T%22">Ishiguro T</searchLink>; Department of Medical Oncology, Department of Medicine, School of Medicine, Showa Medical University, Tokyo 142-8666, Japan.<br /><searchLink fieldCode="AU" term="%22Hirasawa+Y%22">Hirasawa Y</searchLink>; Department of Medical Oncology, Department of Medicine, School of Medicine, Showa Medical University, Tokyo 142-8666, Japan.<br /><searchLink fieldCode="AU" term="%22Ikeda+G%22">Ikeda G</searchLink>; Department of Medical Oncology, Department of Medicine, School of Medicine, Showa Medical University, Tokyo 142-8666, Japan.<br /><searchLink fieldCode="AU" term="%22Shimokawa+M%22">Shimokawa M</searchLink>; Department of Medical Oncology, Department of Medicine, School of Medicine, Showa Medical University, Tokyo 142-8666, Japan.<br /><searchLink fieldCode="AU" term="%22Ariizumi+H%22">Ariizumi H</searchLink>; Department of Medical Oncology, Department of Medicine, School of Medicine, Showa Medical University, Tokyo 142-8666, Japan.<br /><searchLink fieldCode="AU" term="%22Kubota+Y%22">Kubota Y</searchLink>; Department of Medical Oncology, Department of Medicine, School of Medicine, Showa Medical University, Tokyo 142-8666, Japan.<br /><searchLink fieldCode="AU" term="%22Yoshimura+K%22">Yoshimura K</searchLink>; Department of Medical Oncology, Department of Medicine, School of Medicine, Showa Medical University, Tokyo 142-8666, Japan.; Clinical Research Institute for Clinical Pharmacology and Therapeutics, Showa Medical University, Tokyo 157-8577, Japan.; Department of Clinical Immuno Oncology, Clinical Research Institute for Clinical Pharmacology and Therapeutics, Showa Medical University, Tokyo 157-8577, Japan.<br /><searchLink fieldCode="AU" term="%22Kobayashi+S%22">Kobayashi S</searchLink>; Clinical Research Institute for Clinical Pharmacology and Therapeutics, Showa Medical University, Tokyo 157-8577, Japan.<br /><searchLink fieldCode="AU" term="%22Tsunoda+T%22">Tsunoda T</searchLink>; Department of Medical Oncology, Department of Medicine, School of Medicine, Showa Medical University, Tokyo 142-8666, Japan.; Comprehensive Cancer Information Center, Showa Medical University, Tokyo 142-8555, Japan.<br /><searchLink fieldCode="AU" term="%22Horiike+A%22">Horiike A</searchLink>; Department of Medical Oncology, Department of Medicine, School of Medicine, Showa Medical University, Tokyo 142-8666, Japan.<br /><searchLink fieldCode="AU" term="%22Tsuji+M%22">Tsuji M</searchLink>; Pharmacological Research Center, Showa Medical University, Tokyo 142-8555, Japan.<br /><searchLink fieldCode="AU" term="%22Kiuchi+Y%22">Kiuchi Y</searchLink>; Department of Pharmacology, Showa Medical University Graduate School of Medicine, Tokyo 142-8555, Japan.; Pharmacological Research Center, Showa Medical University, Tokyo 142-8555, Japan.<br /><searchLink fieldCode="AU" term="%22Oguchi+T%22">Oguchi T</searchLink>; Department of Pharmacology, Showa Medical University Graduate School of Medicine, Tokyo 142-8555, Japan.; Pharmacological Research Center, Showa Medical University, Tokyo 142-8555, Japan.<br /><searchLink fieldCode="AU" term="%22Wada+S%22">Wada S</searchLink>; Department of Medical Oncology, Department of Medicine, School of Medicine, Showa Medical University, Tokyo 142-8666, Japan.; Department of Clinical Diagnostic Oncology, Clinical Research Institute for Clinical Pharmacology and Therapeutics, Showa Medical University, Tokyo 157-8577, Japan.; Department of Pharmacology, Showa Medical University Graduate School of Medicine, Tokyo 142-8555, Japan.; Clinical Research Institute for Clinical Pharmacology and Therapeutics, Showa Medical University, Tokyo 157-8577, Japan.
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  Data: <searchLink fieldCode="JN" term="%22101691304%22">Biomedicines</searchLink> [Biomedicines] 2025 Dec 10; Vol. 13 (12). <i>Date of Electronic Publication: </i>2025 Dec 10.
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