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Pathogen-Specific Actinium-225 and Lutetium-177 Labeled Antibodies for Treatment of Biofilm-Associated Implant Infections: Initial In Vivo Proof-of-Concept.

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Title: Pathogen-Specific Actinium-225 and Lutetium-177 Labeled Antibodies for Treatment of Biofilm-Associated Implant Infections: Initial In Vivo Proof-of-Concept.
Authors: Nurmohamed FRHA; College of Pharmacy and Nutrition, University of Saskatchewan, 107 Wiggins Road, Saskatoon, SK S7N 2Z4, Canada.; Department of Orthopedics, University Medical Center Utrecht, Heidelberglaan 100, 3585 CX Utrecht, The Netherlands., Allen KJH; College of Pharmacy and Nutrition, University of Saskatchewan, 107 Wiggins Road, Saskatoon, SK S7N 2Z4, Canada., Malo ME; College of Pharmacy and Nutrition, University of Saskatchewan, 107 Wiggins Road, Saskatoon, SK S7N 2Z4, Canada., Frank C; College of Pharmacy and Nutrition, University of Saskatchewan, 107 Wiggins Road, Saskatoon, SK S7N 2Z4, Canada., van Duvenbode JFFH; Department of Orthopedics, University Medical Center Utrecht, Heidelberglaan 100, 3585 CX Utrecht, The Netherlands., van der Wildt B; Department of Nuclear Medicine, University Medical Center Utrecht, Heidelberglaan 100, 3585 CX Utrecht, The Netherlands., Poot AJ; Department of Nuclear Medicine, University Medical Center Utrecht, Heidelberglaan 100, 3585 CX Utrecht, The Netherlands., Lam MGEH; Department of Nuclear Medicine, University Medical Center Utrecht, Heidelberglaan 100, 3585 CX Utrecht, The Netherlands., van Strijp JAG; Department of Medical Microbiology, University Medical Center Utrecht, Heidelberglaan 100, 3585 CX Utrecht, The Netherlands., Nikkels PGJ; Department of Pathology, University Medical Center Utrecht, Heidelberglaan 100, 3585 CX Utrecht, The Netherlands., Vogely HC; Department of Orthopedics, University Medical Center Utrecht, Heidelberglaan 100, 3585 CX Utrecht, The Netherlands., Weinans H; Department of Orthopedics, University Medical Center Utrecht, Heidelberglaan 100, 3585 CX Utrecht, The Netherlands.; Department of Biomechanical Engineering, Delft University of Technology, Mekelweg 2, 2628 CD Delft, The Netherlands., Dadachova E; College of Pharmacy and Nutrition, University of Saskatchewan, 107 Wiggins Road, Saskatoon, SK S7N 2Z4, Canada., van der Wal BCH; Department of Orthopedics, University Medical Center Utrecht, Heidelberglaan 100, 3585 CX Utrecht, The Netherlands.
Source: Antibiotics (Basel, Switzerland) [Antibiotics (Basel)] 2025 Dec 18; Vol. 14 (12). Date of Electronic Publication: 2025 Dec 18.
Publication Type: Journal Article
Journal Info: Publisher: MDPI AG Country of Publication: Switzerland NLM ID: 101637404 Publication Model: Electronic Cited Medium: Print ISSN: 2079-6382 (Print) Linking ISSN: 20796382 NLM ISO Abbreviation: Antibiotics (Basel) Subsets: PubMed not MEDLINE
Database: MEDLINE Ultimate
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  Data: Pathogen-Specific Actinium-225 and Lutetium-177 Labeled Antibodies for Treatment of Biofilm-Associated Implant Infections: Initial In Vivo Proof-of-Concept.
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  Data: <searchLink fieldCode="AU" term="%22Nurmohamed+FRHA%22">Nurmohamed FRHA</searchLink>; College of Pharmacy and Nutrition, University of Saskatchewan, 107 Wiggins Road, Saskatoon, SK S7N 2Z4, Canada.; Department of Orthopedics, University Medical Center Utrecht, Heidelberglaan 100, 3585 CX Utrecht, The Netherlands.<br /><searchLink fieldCode="AU" term="%22Allen+KJH%22">Allen KJH</searchLink>; College of Pharmacy and Nutrition, University of Saskatchewan, 107 Wiggins Road, Saskatoon, SK S7N 2Z4, Canada.<br /><searchLink fieldCode="AU" term="%22Malo+ME%22">Malo ME</searchLink>; College of Pharmacy and Nutrition, University of Saskatchewan, 107 Wiggins Road, Saskatoon, SK S7N 2Z4, Canada.<br /><searchLink fieldCode="AU" term="%22Frank+C%22">Frank C</searchLink>; College of Pharmacy and Nutrition, University of Saskatchewan, 107 Wiggins Road, Saskatoon, SK S7N 2Z4, Canada.<br /><searchLink fieldCode="AU" term="%22van+Duvenbode+JFFH%22">van Duvenbode JFFH</searchLink>; Department of Orthopedics, University Medical Center Utrecht, Heidelberglaan 100, 3585 CX Utrecht, The Netherlands.<br /><searchLink fieldCode="AU" term="%22van+der+Wildt+B%22">van der Wildt B</searchLink>; Department of Nuclear Medicine, University Medical Center Utrecht, Heidelberglaan 100, 3585 CX Utrecht, The Netherlands.<br /><searchLink fieldCode="AU" term="%22Poot+AJ%22">Poot AJ</searchLink>; Department of Nuclear Medicine, University Medical Center Utrecht, Heidelberglaan 100, 3585 CX Utrecht, The Netherlands.<br /><searchLink fieldCode="AU" term="%22Lam+MGEH%22">Lam MGEH</searchLink>; Department of Nuclear Medicine, University Medical Center Utrecht, Heidelberglaan 100, 3585 CX Utrecht, The Netherlands.<br /><searchLink fieldCode="AU" term="%22van+Strijp+JAG%22">van Strijp JAG</searchLink>; Department of Medical Microbiology, University Medical Center Utrecht, Heidelberglaan 100, 3585 CX Utrecht, The Netherlands.<br /><searchLink fieldCode="AU" term="%22Nikkels+PGJ%22">Nikkels PGJ</searchLink>; Department of Pathology, University Medical Center Utrecht, Heidelberglaan 100, 3585 CX Utrecht, The Netherlands.<br /><searchLink fieldCode="AU" term="%22Vogely+HC%22">Vogely HC</searchLink>; Department of Orthopedics, University Medical Center Utrecht, Heidelberglaan 100, 3585 CX Utrecht, The Netherlands.<br /><searchLink fieldCode="AU" term="%22Weinans+H%22">Weinans H</searchLink>; Department of Orthopedics, University Medical Center Utrecht, Heidelberglaan 100, 3585 CX Utrecht, The Netherlands.; Department of Biomechanical Engineering, Delft University of Technology, Mekelweg 2, 2628 CD Delft, The Netherlands.<br /><searchLink fieldCode="AU" term="%22Dadachova+E%22">Dadachova E</searchLink>; College of Pharmacy and Nutrition, University of Saskatchewan, 107 Wiggins Road, Saskatoon, SK S7N 2Z4, Canada.<br /><searchLink fieldCode="AU" term="%22van+der+Wal+BCH%22">van der Wal BCH</searchLink>; Department of Orthopedics, University Medical Center Utrecht, Heidelberglaan 100, 3585 CX Utrecht, The Netherlands.
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  Data: <searchLink fieldCode="JN" term="%22101637404%22">Antibiotics (Basel, Switzerland)</searchLink> [Antibiotics (Basel)] 2025 Dec 18; Vol. 14 (12). <i>Date of Electronic Publication: </i>2025 Dec 18.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22MDPI+AG%22">MDPI AG </searchLink><i>Country of Publication: </i>Switzerland <i>NLM ID: </i>101637404 <i>Publication Model: </i>Electronic <i>Cited Medium: </i>Print <i>ISSN: </i>2079-6382 (Print) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2220796382%22">20796382 </searchLink><i>NLM ISO Abbreviation: </i>Antibiotics (Basel) <i>Subsets: </i>PubMed not MEDLINE
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      – TitleFull: Pathogen-Specific Actinium-225 and Lutetium-177 Labeled Antibodies for Treatment of Biofilm-Associated Implant Infections: Initial In Vivo Proof-of-Concept.
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              Text: 2025 Dec 18
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