Agathisflavone Modulates the Kynurenine Pathway and Glial Inflammatory Responses with Implications for Neuroprotection.

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Title: Agathisflavone Modulates the Kynurenine Pathway and Glial Inflammatory Responses with Implications for Neuroprotection.
Authors: Argolo DS; Laboratory of Neurochemistry and Cellular Biology, Department of Biochemistry and Biophysics, Institute of Health Sciences, Federal University of Bahia, Av. Reitor Miguel Calmon S/N, Salvador 40231-300, BA, Brazil., Oliveira LMG; Laboratory of Neurochemistry and Cellular Biology, Department of Biochemistry and Biophysics, Institute of Health Sciences, Federal University of Bahia, Av. Reitor Miguel Calmon S/N, Salvador 40231-300, BA, Brazil., Santos CCD; Laboratory of Neurochemistry and Cellular Biology, Department of Biochemistry and Biophysics, Institute of Health Sciences, Federal University of Bahia, Av. Reitor Miguel Calmon S/N, Salvador 40231-300, BA, Brazil., da Penha Gonçalves LV; Laboratory of Neurochemistry and Cellular Biology, Department of Biochemistry and Biophysics, Institute of Health Sciences, Federal University of Bahia, Av. Reitor Miguel Calmon S/N, Salvador 40231-300, BA, Brazil., Loiola EC; Center of Biotechnology and Cell Therapy, São Rafael Hospital, D'Or Institute for Research and Education (IDOR), Av. São Rafael, 2152-São Rafael, Salvador 41253-190, BA, Brazil., de Freitas Souza BS; Center of Biotechnology and Cell Therapy, São Rafael Hospital, D'Or Institute for Research and Education (IDOR), Av. São Rafael, 2152-São Rafael, Salvador 41253-190, BA, Brazil., Barreto GE; Neuroendocrine Pharmacology Lab, Department of Biological Sciences, Faculty of Science and Engineering, University of Limerick, V94 T9PX Limerick, Ireland., Butt AM; School of Medicine, Pharmacy and Biomedical Sciences, University of Portsmouth, Portsmouth PO1 2UP, UK., David JM; Department of General and Inorganic Chemistry, Institute of Chemistry, University Federal da Bahia, Salvador 40170-110, BA, Brazil., Branco A; Laboratory of Phytochemistry, Department of Health, State University of Feira de Santana, Av. Transnordestina, s/n, Feira de Santana 44036-900, BA, Brazil., Reis IMA; Laboratory of Phytochemistry, Department of Health, State University of Feira de Santana, Av. Transnordestina, s/n, Feira de Santana 44036-900, BA, Brazil., Azevedo-Silva A; Laboratory of Phytochemistry, Department of Health, State University of Feira de Santana, Av. Transnordestina, s/n, Feira de Santana 44036-900, BA, Brazil., Costa SL; Laboratory of Neurochemistry and Cellular Biology, Department of Biochemistry and Biophysics, Institute of Health Sciences, Federal University of Bahia, Av. Reitor Miguel Calmon S/N, Salvador 40231-300, BA, Brazil.; National Institute of Translational Neuroscience (INCT-CNPq), Federal University of Rio de Janeiro, Rio de Janeiro 21941-90, RJ, Brazil., Costa MFD; Laboratory of Neurochemistry and Cellular Biology, Department of Biochemistry and Biophysics, Institute of Health Sciences, Federal University of Bahia, Av. Reitor Miguel Calmon S/N, Salvador 40231-300, BA, Brazil.; National Institute of Translational Neuroscience (INCT-CNPq), Federal University of Rio de Janeiro, Rio de Janeiro 21941-90, RJ, Brazil.
Source: International journal of molecular sciences [Int J Mol Sci] 2025 Dec 11; Vol. 26 (24). Date of Electronic Publication: 2025 Dec 11.
Publication Type: Journal Article
Journal Info: Publisher: MDPI Country of Publication: Switzerland NLM ID: 101092791 Publication Model: Electronic Cited Medium: Internet ISSN: 1422-0067 (Electronic) Linking ISSN: 14220067 NLM ISO Abbreviation: Int J Mol Sci Subsets: MEDLINE
Database: MEDLINE Ultimate
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