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Association of plasma homocysteine levels with the presence of intracranial aneurysms and the risk of rupture: A systematic review and meta-analysis.

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Title: Association of plasma homocysteine levels with the presence of intracranial aneurysms and the risk of rupture: A systematic review and meta-analysis.
Authors: Akhavan-Sigari A; Neurosurgery Simulation and Innovation Laboratory, Mayo Clinic, Phoenix, AZ, USA; Precision Neuro-Therapeutics Innovation Laboratory, Mayo Clinic, Phoenix, AZ, USA; Department of Neurosurgery, Stanford University School of Medicine, Stanford, CA, USA., Olson V; Neurosurgery Simulation and Innovation Laboratory, Mayo Clinic, Phoenix, AZ, USA; Precision Neuro-Therapeutics Innovation Laboratory, Mayo Clinic, Phoenix, AZ, USA., Pachón-Londoño MJ; Neurosurgery Simulation and Innovation Laboratory, Mayo Clinic, Phoenix, AZ, USA; Precision Neuro-Therapeutics Innovation Laboratory, Mayo Clinic, Phoenix, AZ, USA., Moussalem CK; Neurosurgery Simulation and Innovation Laboratory, Mayo Clinic, Phoenix, AZ, USA; Precision Neuro-Therapeutics Innovation Laboratory, Mayo Clinic, Phoenix, AZ, USA; Department of Neurological Surgery, Mayo Clinic, Phoenix, AZ, USA., Wang Z; Mayo Clinic Evidence-Based Practice Center, Rochester, MN, USA; Robert D. and Patricia E. Kern Center for the Science of Health Care Delivery, Mayo Clinic, Rochester, MN, USA., Park DJ; Department of Neurosurgery, Stanford University School of Medicine, Stanford, CA, USA., Krishna C; Neurosurgery Simulation and Innovation Laboratory, Mayo Clinic, Phoenix, AZ, USA; Precision Neuro-Therapeutics Innovation Laboratory, Mayo Clinic, Phoenix, AZ, USA; Department of Neurological Surgery, Mayo Clinic, Phoenix, AZ, USA., Chang SD; Department of Neurosurgery, Stanford University School of Medicine, Stanford, CA, USA., Meyer FB; Department of Neurological Surgery, Mayo Clinic, Rochester, MN, USA., Bendok BR; Neurosurgery Simulation and Innovation Laboratory, Mayo Clinic, Phoenix, AZ, USA; Precision Neuro-Therapeutics Innovation Laboratory, Mayo Clinic, Phoenix, AZ, USA; Department of Neurological Surgery, Mayo Clinic, Phoenix, AZ, USA; Chair, Department of Neurological Surgery, Mayo Clinic, Phoenix, AZ, USA; Department of Radiology, Mayo Clinic, Phoenix, AZ, USA; Department of Otolaryngology - Head & Neck Surgery, Mayo Clinic, Phoenix, AZ, USA. Electronic address: bendok.bernard@mayo.edu.
Source: Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia [J Clin Neurosci] 2026 Mar; Vol. 145, pp. 111830. Date of Electronic Publication: 2025 Dec 29.
Publication Type: Journal Article; Systematic Review; Meta-Analysis; Review
Journal Info: Publisher: Churchill Livingstone Country of Publication: Scotland NLM ID: 9433352 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1532-2653 (Electronic) Linking ISSN: 09675868 NLM ISO Abbreviation: J Clin Neurosci Subsets: MEDLINE
Database: MEDLINE Ultimate
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PubType: Academic Journal
PubTypeId: academicJournal
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  Data: Association of plasma homocysteine levels with the presence of intracranial aneurysms and the risk of rupture: A systematic review and meta-analysis.
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  Data: <searchLink fieldCode="AU" term="%22Akhavan-Sigari+A%22">Akhavan-Sigari A</searchLink>; Neurosurgery Simulation and Innovation Laboratory, Mayo Clinic, Phoenix, AZ, USA; Precision Neuro-Therapeutics Innovation Laboratory, Mayo Clinic, Phoenix, AZ, USA; Department of Neurosurgery, Stanford University School of Medicine, Stanford, CA, USA.<br /><searchLink fieldCode="AU" term="%22Olson+V%22">Olson V</searchLink>; Neurosurgery Simulation and Innovation Laboratory, Mayo Clinic, Phoenix, AZ, USA; Precision Neuro-Therapeutics Innovation Laboratory, Mayo Clinic, Phoenix, AZ, USA.<br /><searchLink fieldCode="AU" term="%22Pachón-Londoño+MJ%22">Pachón-Londoño MJ</searchLink>; Neurosurgery Simulation and Innovation Laboratory, Mayo Clinic, Phoenix, AZ, USA; Precision Neuro-Therapeutics Innovation Laboratory, Mayo Clinic, Phoenix, AZ, USA.<br /><searchLink fieldCode="AU" term="%22Moussalem+CK%22">Moussalem CK</searchLink>; Neurosurgery Simulation and Innovation Laboratory, Mayo Clinic, Phoenix, AZ, USA; Precision Neuro-Therapeutics Innovation Laboratory, Mayo Clinic, Phoenix, AZ, USA; Department of Neurological Surgery, Mayo Clinic, Phoenix, AZ, USA.<br /><searchLink fieldCode="AU" term="%22Wang+Z%22">Wang Z</searchLink>; Mayo Clinic Evidence-Based Practice Center, Rochester, MN, USA; Robert D. and Patricia E. Kern Center for the Science of Health Care Delivery, Mayo Clinic, Rochester, MN, USA.<br /><searchLink fieldCode="AU" term="%22Park+DJ%22">Park DJ</searchLink>; Department of Neurosurgery, Stanford University School of Medicine, Stanford, CA, USA.<br /><searchLink fieldCode="AU" term="%22Krishna+C%22">Krishna C</searchLink>; Neurosurgery Simulation and Innovation Laboratory, Mayo Clinic, Phoenix, AZ, USA; Precision Neuro-Therapeutics Innovation Laboratory, Mayo Clinic, Phoenix, AZ, USA; Department of Neurological Surgery, Mayo Clinic, Phoenix, AZ, USA.<br /><searchLink fieldCode="AU" term="%22Chang+SD%22">Chang SD</searchLink>; Department of Neurosurgery, Stanford University School of Medicine, Stanford, CA, USA.<br /><searchLink fieldCode="AU" term="%22Meyer+FB%22">Meyer FB</searchLink>; Department of Neurological Surgery, Mayo Clinic, Rochester, MN, USA.<br /><searchLink fieldCode="AU" term="%22Bendok+BR%22">Bendok BR</searchLink>; Neurosurgery Simulation and Innovation Laboratory, Mayo Clinic, Phoenix, AZ, USA; Precision Neuro-Therapeutics Innovation Laboratory, Mayo Clinic, Phoenix, AZ, USA; Department of Neurological Surgery, Mayo Clinic, Phoenix, AZ, USA; Chair, Department of Neurological Surgery, Mayo Clinic, Phoenix, AZ, USA; Department of Radiology, Mayo Clinic, Phoenix, AZ, USA; Department of Otolaryngology - Head & Neck Surgery, Mayo Clinic, Phoenix, AZ, USA. Electronic address: bendok.bernard@mayo.edu.
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  Data: <searchLink fieldCode="JN" term="%229433352%22">Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia</searchLink> [J Clin Neurosci] 2026 Mar; Vol. 145, pp. 111830. <i>Date of Electronic Publication: </i>2025 Dec 29.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Churchill+Livingstone%22">Churchill Livingstone </searchLink><i>Country of Publication: </i>Scotland <i>NLM ID: </i>9433352 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1532-2653 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2209675868%22">09675868 </searchLink><i>NLM ISO Abbreviation: </i>J Clin Neurosci <i>Subsets: </i>MEDLINE
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        Value: 10.1016/j.jocn.2025.111830
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        Text: English
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        StartPage: 111830
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              Text: 2026 Mar
              Type: published
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