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Defining patient-centered amyloid PET thresholds for the onset of tauopathy in Alzheimer's disease.

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Title: Defining patient-centered amyloid PET thresholds for the onset of tauopathy in Alzheimer's disease.
Authors: Zhu Z; Institute for Stroke and Dementia Research (ISD), University Hospital, LMU Munich, Munich, Germany., Steward A; Institute for Stroke and Dementia Research (ISD), University Hospital, LMU Munich, Munich, Germany., Dehsarvi A; Institute for Stroke and Dementia Research (ISD), University Hospital, LMU Munich, Munich, Germany., Roemer-Cassiano SN; Institute for Stroke and Dementia Research (ISD), University Hospital, LMU Munich, Munich, Germany.; Department of Neurology, University Hospital, LMU Munich, Munich, Germany.; Max Planck School of Cognition, Leipzig, Germany., Dewenter A; Institute for Stroke and Dementia Research (ISD), University Hospital, LMU Munich, Munich, Germany., Biel D; Institute for Stroke and Dementia Research (ISD), University Hospital, LMU Munich, Munich, Germany., Hirsch F; Institute for Stroke and Dementia Research (ISD), University Hospital, LMU Munich, Munich, Germany., Frontzkowski L; Institute for Stroke and Dementia Research (ISD), University Hospital, LMU Munich, Munich, Germany.; Department of Nuclear Medicine, University Hospital, LMU Munich, Munich, Germany., Pescoller J; Institute for Stroke and Dementia Research (ISD), University Hospital, LMU Munich, Munich, Germany., Klonowski M; Institute for Stroke and Dementia Research (ISD), University Hospital, LMU Munich, Munich, Germany., Gnörich J; Department of Nuclear Medicine, University Hospital, LMU Munich, Munich, Germany., Pontecorvo MJ; Eli Lilly and Company, Indianapolis, Indiana, USA., Shcherbinin S; Eli Lilly and Company, Indianapolis, Indiana, USA., Schöll M; Department of Psychiatry and Neurochemistry, The Sahlgrenska Academy, Institute of Neuroscience and Physiology, University of Gothenburg, Gothenburg, Sweden.; Wallenberg Centre for Molecular and Translational Medicine and the Department of Psychiatry and Neurochemistry, University of Gothenburg, Gothenburg, Sweden.; Dementia Research Centre, Queen Square Institute of Neurology, University College London, London, UK., Buckley R; Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts, USA., Ossenkoppele R; Department of Clinical Sciences Malmö, Clinical Memory Research Unit, Faculty of Medicine, Lund University, Lund, Sweden.; Alzheimer Center Amsterdam, Neurology, Vrije Universiteit Amsterdam, Amsterdam, the Netherlands.; Amsterdam Neuroscience, Neurodegeneration, Amsterdam, the Netherlands., Xie F; Department of Nuclear Medicine & PET Center, Huashan Hospital, Fudan University, Shanghai, China., Guo T; Institute of Neurological and Psychiatric Disorders, Shenzhen Bay Laboratory, Shenzhen, China.; Institute of Biomedical Engineering, Peking University Shenzhen Graduate School, Shenzhen, China., Höglinger G; Department of Neurology, University Hospital, LMU Munich, Munich, Germany.; German Center for Neurodegenerative Diseases (DZNE), Munich, Germany.; Munich Cluster for Systems Neurology (SyNergy), Munich, Germany., Brendel M; Department of Nuclear Medicine, University Hospital, LMU Munich, Munich, Germany.; German Center for Neurodegenerative Diseases (DZNE), Munich, Germany.; Munich Cluster for Systems Neurology (SyNergy), Munich, Germany., Franzmeier N; Institute for Stroke and Dementia Research (ISD), University Hospital, LMU Munich, Munich, Germany.; Department of Psychiatry and Neurochemistry, The Sahlgrenska Academy, Institute of Neuroscience and Physiology, University of Gothenburg, Gothenburg, Sweden.; Munich Cluster for Systems Neurology (SyNergy), Munich, Germany.
Corporate Authors: Alzheimer's Disease Neuroimaging Initiative
Source: Alzheimer's & dementia : the journal of the Alzheimer's Association [Alzheimers Dement] 2026 Jan; Vol. 22 (1), pp. e71064.
Publication Type: Journal Article
Journal Info: Publisher: John Wiley & Sons, Ltd Country of Publication: United States NLM ID: 101231978 Publication Model: Print Cited Medium: Internet ISSN: 1552-5279 (Electronic) Linking ISSN: 15525260 NLM ISO Abbreviation: Alzheimers Dement Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Defining patient-centered amyloid PET thresholds for the onset of tauopathy in Alzheimer's disease.
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  Data: <searchLink fieldCode="AU" term="%22Zhu+Z%22">Zhu Z</searchLink>; Institute for Stroke and Dementia Research (ISD), University Hospital, LMU Munich, Munich, Germany.<br /><searchLink fieldCode="AU" term="%22Steward+A%22">Steward A</searchLink>; Institute for Stroke and Dementia Research (ISD), University Hospital, LMU Munich, Munich, Germany.<br /><searchLink fieldCode="AU" term="%22Dehsarvi+A%22">Dehsarvi A</searchLink>; Institute for Stroke and Dementia Research (ISD), University Hospital, LMU Munich, Munich, Germany.<br /><searchLink fieldCode="AU" term="%22Roemer-Cassiano+SN%22">Roemer-Cassiano SN</searchLink>; Institute for Stroke and Dementia Research (ISD), University Hospital, LMU Munich, Munich, Germany.; Department of Neurology, University Hospital, LMU Munich, Munich, Germany.; Max Planck School of Cognition, Leipzig, Germany.<br /><searchLink fieldCode="AU" term="%22Dewenter+A%22">Dewenter A</searchLink>; Institute for Stroke and Dementia Research (ISD), University Hospital, LMU Munich, Munich, Germany.<br /><searchLink fieldCode="AU" term="%22Biel+D%22">Biel D</searchLink>; Institute for Stroke and Dementia Research (ISD), University Hospital, LMU Munich, Munich, Germany.<br /><searchLink fieldCode="AU" term="%22Hirsch+F%22">Hirsch F</searchLink>; Institute for Stroke and Dementia Research (ISD), University Hospital, LMU Munich, Munich, Germany.<br /><searchLink fieldCode="AU" term="%22Frontzkowski+L%22">Frontzkowski L</searchLink>; Institute for Stroke and Dementia Research (ISD), University Hospital, LMU Munich, Munich, Germany.; Department of Nuclear Medicine, University Hospital, LMU Munich, Munich, Germany.<br /><searchLink fieldCode="AU" term="%22Pescoller+J%22">Pescoller J</searchLink>; Institute for Stroke and Dementia Research (ISD), University Hospital, LMU Munich, Munich, Germany.<br /><searchLink fieldCode="AU" term="%22Klonowski+M%22">Klonowski M</searchLink>; Institute for Stroke and Dementia Research (ISD), University Hospital, LMU Munich, Munich, Germany.<br /><searchLink fieldCode="AU" term="%22Gnörich+J%22">Gnörich J</searchLink>; Department of Nuclear Medicine, University Hospital, LMU Munich, Munich, Germany.<br /><searchLink fieldCode="AU" term="%22Pontecorvo+MJ%22">Pontecorvo MJ</searchLink>; Eli Lilly and Company, Indianapolis, Indiana, USA.<br /><searchLink fieldCode="AU" term="%22Shcherbinin+S%22">Shcherbinin S</searchLink>; Eli Lilly and Company, Indianapolis, Indiana, USA.<br /><searchLink fieldCode="AU" term="%22Schöll+M%22">Schöll M</searchLink>; Department of Psychiatry and Neurochemistry, The Sahlgrenska Academy, Institute of Neuroscience and Physiology, University of Gothenburg, Gothenburg, Sweden.; Wallenberg Centre for Molecular and Translational Medicine and the Department of Psychiatry and Neurochemistry, University of Gothenburg, Gothenburg, Sweden.; Dementia Research Centre, Queen Square Institute of Neurology, University College London, London, UK.<br /><searchLink fieldCode="AU" term="%22Buckley+R%22">Buckley R</searchLink>; Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts, USA.<br /><searchLink fieldCode="AU" term="%22Ossenkoppele+R%22">Ossenkoppele R</searchLink>; Department of Clinical Sciences Malmö, Clinical Memory Research Unit, Faculty of Medicine, Lund University, Lund, Sweden.; Alzheimer Center Amsterdam, Neurology, Vrije Universiteit Amsterdam, Amsterdam, the Netherlands.; Amsterdam Neuroscience, Neurodegeneration, Amsterdam, the Netherlands.<br /><searchLink fieldCode="AU" term="%22Xie+F%22">Xie F</searchLink>; Department of Nuclear Medicine & PET Center, Huashan Hospital, Fudan University, Shanghai, China.<br /><searchLink fieldCode="AU" term="%22Guo+T%22">Guo T</searchLink>; Institute of Neurological and Psychiatric Disorders, Shenzhen Bay Laboratory, Shenzhen, China.; Institute of Biomedical Engineering, Peking University Shenzhen Graduate School, Shenzhen, China.<br /><searchLink fieldCode="AU" term="%22Höglinger+G%22">Höglinger G</searchLink>; Department of Neurology, University Hospital, LMU Munich, Munich, Germany.; German Center for Neurodegenerative Diseases (DZNE), Munich, Germany.; Munich Cluster for Systems Neurology (SyNergy), Munich, Germany.<br /><searchLink fieldCode="AU" term="%22Brendel+M%22">Brendel M</searchLink>; Department of Nuclear Medicine, University Hospital, LMU Munich, Munich, Germany.; German Center for Neurodegenerative Diseases (DZNE), Munich, Germany.; Munich Cluster for Systems Neurology (SyNergy), Munich, Germany.<br /><searchLink fieldCode="AU" term="%22Franzmeier+N%22">Franzmeier N</searchLink>; Institute for Stroke and Dementia Research (ISD), University Hospital, LMU Munich, Munich, Germany.; Department of Psychiatry and Neurochemistry, The Sahlgrenska Academy, Institute of Neuroscience and Physiology, University of Gothenburg, Gothenburg, Sweden.; Munich Cluster for Systems Neurology (SyNergy), Munich, Germany.
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  Data: <searchLink fieldCode="JN" term="%22101231978%22">Alzheimer's & dementia : the journal of the Alzheimer's Association</searchLink> [Alzheimers Dement] 2026 Jan; Vol. 22 (1), pp. e71064.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22John+Wiley+%26+Sons%2C+Ltd%22">John Wiley & Sons, Ltd </searchLink><i>Country of Publication: </i>United States <i>NLM ID: </i>101231978 <i>Publication Model: </i>Print <i>Cited Medium: </i>Internet <i>ISSN: </i>1552-5279 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2215525260%22">15525260 </searchLink><i>NLM ISO Abbreviation: </i>Alzheimers Dement <i>Subsets: </i>MEDLINE
PLink https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=mdl&AN=41485137
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              Text: 2026 Jan
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