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Investigation of Monoclonal Antibody Pharmacokinetics in Pediatric Population and Characterization Using a Platform PBPK Model.

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Title: Investigation of Monoclonal Antibody Pharmacokinetics in Pediatric Population and Characterization Using a Platform PBPK Model.
Authors: Kumar M; Department of Pharmaceutical Sciences, School of Pharmacy and Pharmaceutical Sciences,, The State University of New York at Buffalo, 455 Pharmacy Building, Buffalo, New York, 14214-8033, USA., Lanke S; Department of Pharmaceutical Sciences, School of Pharmacy and Pharmaceutical Sciences,, The State University of New York at Buffalo, 455 Pharmacy Building, Buffalo, New York, 14214-8033, USA., Shah DK; Department of Pharmaceutical Sciences, School of Pharmacy and Pharmaceutical Sciences,, The State University of New York at Buffalo, 455 Pharmacy Building, Buffalo, New York, 14214-8033, USA. dshah4@buffalo.edu.
Source: The AAPS journal [AAPS J] 2026 Jan 05; Vol. 28 (1), pp. 44. Date of Electronic Publication: 2026 Jan 05.
Publication Type: Journal Article
Journal Info: Publisher: American Association of Pharmaceutical Scientists Country of Publication: United States NLM ID: 101223209 Publication Model: Electronic Cited Medium: Internet ISSN: 1550-7416 (Electronic) Linking ISSN: 15507416 NLM ISO Abbreviation: AAPS J Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: <searchLink fieldCode="AU" term="%22Kumar+M%22">Kumar M</searchLink>; Department of Pharmaceutical Sciences, School of Pharmacy and Pharmaceutical Sciences,, The State University of New York at Buffalo, 455 Pharmacy Building, Buffalo, New York, 14214-8033, USA.<br /><searchLink fieldCode="AU" term="%22Lanke+S%22">Lanke S</searchLink>; Department of Pharmaceutical Sciences, School of Pharmacy and Pharmaceutical Sciences,, The State University of New York at Buffalo, 455 Pharmacy Building, Buffalo, New York, 14214-8033, USA.<br /><searchLink fieldCode="AU" term="%22Shah+DK%22">Shah DK</searchLink>; Department of Pharmaceutical Sciences, School of Pharmacy and Pharmaceutical Sciences,, The State University of New York at Buffalo, 455 Pharmacy Building, Buffalo, New York, 14214-8033, USA. dshah4@buffalo.edu.
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  Data: <searchLink fieldCode="JN" term="%22101223209%22">The AAPS journal</searchLink> [AAPS J] 2026 Jan 05; Vol. 28 (1), pp. 44. <i>Date of Electronic Publication: </i>2026 Jan 05.
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        Value: 10.1208/s12248-025-01179-7
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      – Code: eng
        Text: English
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        StartPage: 44
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      – TitleFull: Investigation of Monoclonal Antibody Pharmacokinetics in Pediatric Population and Characterization Using a Platform PBPK Model.
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            NameFull: Kumar M
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            NameFull: Lanke S
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            – D: 05
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              Text: 2026 Jan 05
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              Y: 2026
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