SCALE: unsupervised multiscale domain identification in spatial omics data.

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Title: SCALE: unsupervised multiscale domain identification in spatial omics data.
Authors: Yousefi B; Institute of Medical Systems Bioinformatics, Center for Biomedical AI (bAIome), Center for Molecular Neurobiology (ZMNH), University Medical Center Hamburg-Eppendorf, Hamburg 20251, Germany.; German Center for Child and Adolescent Health (DZKJ), partner site Hamburg, University Medical Center Hamburg-Eppendorf, Hamburg 20251, Germany., Schaub DP; Institute of Medical Systems Bioinformatics, Center for Biomedical AI (bAIome), Center for Molecular Neurobiology (ZMNH), University Medical Center Hamburg-Eppendorf, Hamburg 20251, Germany.; III. Department of Medicine, University Medical Center Hamburg-Eppendorf, Hamburg 20251, Germany., Khatri R; Institute of Medical Systems Bioinformatics, Center for Biomedical AI (bAIome), Center for Molecular Neurobiology (ZMNH), University Medical Center Hamburg-Eppendorf, Hamburg 20251, Germany.; Hamburg Center for Translational Immunology (HCTI), University Medical Center Hamburg-Eppendorf, Hamburg 20251, Germany., Kaiser N; Institute of Medical Systems Bioinformatics, Center for Biomedical AI (bAIome), Center for Molecular Neurobiology (ZMNH), University Medical Center Hamburg-Eppendorf, Hamburg 20251, Germany.; III. Department of Medicine, University Medical Center Hamburg-Eppendorf, Hamburg 20251, Germany., Kuehl M; Department of Clinical Medicine, Aarhus University, Aarhus 8200, Denmark.; Department of Pathology, Aarhus University Hospital, Aarhus 8200, Denmark., Ly C; Institute of Medical Systems Bioinformatics, Center for Biomedical AI (bAIome), Center for Molecular Neurobiology (ZMNH), University Medical Center Hamburg-Eppendorf, Hamburg 20251, Germany.; Institute of Systems Immunology, University Medical Center Hamburg-Eppendorf, Hamburg 20251, Germany., Puelles VG; III. Department of Medicine, University Medical Center Hamburg-Eppendorf, Hamburg 20251, Germany.; Department of Clinical Medicine, Aarhus University, Aarhus 8200, Denmark.; Department of Pathology, Aarhus University Hospital, Aarhus 8200, Denmark.; Hamburg Center for Kidney Health (HCKH), University Medical Center Hamburg-Eppendorf, Hamburg 20251, Germany., Huber TB; III. Department of Medicine, University Medical Center Hamburg-Eppendorf, Hamburg 20251, Germany.; Hamburg Center for Translational Immunology (HCTI), University Medical Center Hamburg-Eppendorf, Hamburg 20251, Germany.; Hamburg Center for Kidney Health (HCKH), University Medical Center Hamburg-Eppendorf, Hamburg 20251, Germany., Prinz I; Hamburg Center for Translational Immunology (HCTI), University Medical Center Hamburg-Eppendorf, Hamburg 20251, Germany.; Institute of Systems Immunology, University Medical Center Hamburg-Eppendorf, Hamburg 20251, Germany., Krebs CF; III. Department of Medicine, University Medical Center Hamburg-Eppendorf, Hamburg 20251, Germany.; Hamburg Center for Translational Immunology (HCTI), University Medical Center Hamburg-Eppendorf, Hamburg 20251, Germany.; Hamburg Center for Kidney Health (HCKH), University Medical Center Hamburg-Eppendorf, Hamburg 20251, Germany., Panzer U; III. Department of Medicine, University Medical Center Hamburg-Eppendorf, Hamburg 20251, Germany.; Hamburg Center for Translational Immunology (HCTI), University Medical Center Hamburg-Eppendorf, Hamburg 20251, Germany.; Hamburg Center for Kidney Health (HCKH), University Medical Center Hamburg-Eppendorf, Hamburg 20251, Germany., Bonn S; Institute of Medical Systems Bioinformatics, Center for Biomedical AI (bAIome), Center for Molecular Neurobiology (ZMNH), University Medical Center Hamburg-Eppendorf, Hamburg 20251, Germany.; German Center for Child and Adolescent Health (DZKJ), partner site Hamburg, University Medical Center Hamburg-Eppendorf, Hamburg 20251, Germany.; Hamburg Center for Translational Immunology (HCTI), University Medical Center Hamburg-Eppendorf, Hamburg 20251, Germany.; Hamburg Center for Kidney Health (HCKH), University Medical Center Hamburg-Eppendorf, Hamburg 20251, Germany.
Source: Nucleic acids research [Nucleic Acids Res] 2026 Jan 05; Vol. 54 (1).
Publication Type: Journal Article
Journal Info: Publisher: Oxford University Press Country of Publication: England NLM ID: 0411011 Publication Model: Print Cited Medium: Internet ISSN: 1362-4962 (Electronic) Linking ISSN: 03051048 NLM ISO Abbreviation: Nucleic Acids Res Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: SCALE: unsupervised multiscale domain identification in spatial omics data.
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  Data: <searchLink fieldCode="AU" term="%22Yousefi+B%22">Yousefi B</searchLink>; Institute of Medical Systems Bioinformatics, Center for Biomedical AI (bAIome), Center for Molecular Neurobiology (ZMNH), University Medical Center Hamburg-Eppendorf, Hamburg 20251, Germany.; German Center for Child and Adolescent Health (DZKJ), partner site Hamburg, University Medical Center Hamburg-Eppendorf, Hamburg 20251, Germany.<br /><searchLink fieldCode="AU" term="%22Schaub+DP%22">Schaub DP</searchLink>; Institute of Medical Systems Bioinformatics, Center for Biomedical AI (bAIome), Center for Molecular Neurobiology (ZMNH), University Medical Center Hamburg-Eppendorf, Hamburg 20251, Germany.; III. Department of Medicine, University Medical Center Hamburg-Eppendorf, Hamburg 20251, Germany.<br /><searchLink fieldCode="AU" term="%22Khatri+R%22">Khatri R</searchLink>; Institute of Medical Systems Bioinformatics, Center for Biomedical AI (bAIome), Center for Molecular Neurobiology (ZMNH), University Medical Center Hamburg-Eppendorf, Hamburg 20251, Germany.; Hamburg Center for Translational Immunology (HCTI), University Medical Center Hamburg-Eppendorf, Hamburg 20251, Germany.<br /><searchLink fieldCode="AU" term="%22Kaiser+N%22">Kaiser N</searchLink>; Institute of Medical Systems Bioinformatics, Center for Biomedical AI (bAIome), Center for Molecular Neurobiology (ZMNH), University Medical Center Hamburg-Eppendorf, Hamburg 20251, Germany.; III. Department of Medicine, University Medical Center Hamburg-Eppendorf, Hamburg 20251, Germany.<br /><searchLink fieldCode="AU" term="%22Kuehl+M%22">Kuehl M</searchLink>; Department of Clinical Medicine, Aarhus University, Aarhus 8200, Denmark.; Department of Pathology, Aarhus University Hospital, Aarhus 8200, Denmark.<br /><searchLink fieldCode="AU" term="%22Ly+C%22">Ly C</searchLink>; Institute of Medical Systems Bioinformatics, Center for Biomedical AI (bAIome), Center for Molecular Neurobiology (ZMNH), University Medical Center Hamburg-Eppendorf, Hamburg 20251, Germany.; Institute of Systems Immunology, University Medical Center Hamburg-Eppendorf, Hamburg 20251, Germany.<br /><searchLink fieldCode="AU" term="%22Puelles+VG%22">Puelles VG</searchLink>; III. Department of Medicine, University Medical Center Hamburg-Eppendorf, Hamburg 20251, Germany.; Department of Clinical Medicine, Aarhus University, Aarhus 8200, Denmark.; Department of Pathology, Aarhus University Hospital, Aarhus 8200, Denmark.; Hamburg Center for Kidney Health (HCKH), University Medical Center Hamburg-Eppendorf, Hamburg 20251, Germany.<br /><searchLink fieldCode="AU" term="%22Huber+TB%22">Huber TB</searchLink>; III. Department of Medicine, University Medical Center Hamburg-Eppendorf, Hamburg 20251, Germany.; Hamburg Center for Translational Immunology (HCTI), University Medical Center Hamburg-Eppendorf, Hamburg 20251, Germany.; Hamburg Center for Kidney Health (HCKH), University Medical Center Hamburg-Eppendorf, Hamburg 20251, Germany.<br /><searchLink fieldCode="AU" term="%22Prinz+I%22">Prinz I</searchLink>; Hamburg Center for Translational Immunology (HCTI), University Medical Center Hamburg-Eppendorf, Hamburg 20251, Germany.; Institute of Systems Immunology, University Medical Center Hamburg-Eppendorf, Hamburg 20251, Germany.<br /><searchLink fieldCode="AU" term="%22Krebs+CF%22">Krebs CF</searchLink>; III. Department of Medicine, University Medical Center Hamburg-Eppendorf, Hamburg 20251, Germany.; Hamburg Center for Translational Immunology (HCTI), University Medical Center Hamburg-Eppendorf, Hamburg 20251, Germany.; Hamburg Center for Kidney Health (HCKH), University Medical Center Hamburg-Eppendorf, Hamburg 20251, Germany.<br /><searchLink fieldCode="AU" term="%22Panzer+U%22">Panzer U</searchLink>; III. Department of Medicine, University Medical Center Hamburg-Eppendorf, Hamburg 20251, Germany.; Hamburg Center for Translational Immunology (HCTI), University Medical Center Hamburg-Eppendorf, Hamburg 20251, Germany.; Hamburg Center for Kidney Health (HCKH), University Medical Center Hamburg-Eppendorf, Hamburg 20251, Germany.<br /><searchLink fieldCode="AU" term="%22Bonn+S%22">Bonn S</searchLink>; Institute of Medical Systems Bioinformatics, Center for Biomedical AI (bAIome), Center for Molecular Neurobiology (ZMNH), University Medical Center Hamburg-Eppendorf, Hamburg 20251, Germany.; German Center for Child and Adolescent Health (DZKJ), partner site Hamburg, University Medical Center Hamburg-Eppendorf, Hamburg 20251, Germany.; Hamburg Center for Translational Immunology (HCTI), University Medical Center Hamburg-Eppendorf, Hamburg 20251, Germany.; Hamburg Center for Kidney Health (HCKH), University Medical Center Hamburg-Eppendorf, Hamburg 20251, Germany.
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              Text: 2026 Jan 05
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