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Inhibition of histone lysine demethylase restores learning and memory in aged mice.

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Title: Inhibition of histone lysine demethylase restores learning and memory in aged mice.
Authors: Bhatt SU; Centre for Craniofacial and Regenerative Biology, Guy's Hospital, King's College London, SE1 9RT., MacBean L; Department of Clinical and Biomedical Sciences, University of Exeter Medical School, Hatherly Laboratories, Prince of Wales Road, University of Exeter, Exeter, EX4 4PS, UK., Kramár E; Department of Neurobiology and Behavior, School of Biological Sciences, University of California Irvine, Irvine, California, California 92697., Pérez-Sisqués L; MRC Centre for Neurodevelopmental Disorders, New Hunt's House, King's College London, London SE1 1UL, UK., Smethurst P; MSD, R&D Innovation Centre, 120 Moorgate, London, EC2M 6UR., Robb JL; Department of Clinical and Biomedical Sciences, University of Exeter Medical School, Hatherly Laboratories, Prince of Wales Road, University of Exeter, Exeter, EX4 4PS, UK., Jindal N; Department of Clinical and Biomedical Sciences, University of Exeter Medical School, Hatherly Laboratories, Prince of Wales Road, University of Exeter, Exeter, EX4 4PS, UK., Fetterly TL; Department of Neurobiology and Behavior, School of Biological Sciences, University of California Irvine, Irvine, California, California 92697., Graham A; Centre for Craniofacial and Regenerative Biology, Guy's Hospital, King's College London, SE1 9RT., Wood MA; Department of Neurobiology and Behavior, School of Biological Sciences, University of California Irvine, Irvine, California, California 92697., Gillotin S; MSD, R&D Innovation Centre, 120 Moorgate, London, EC2M 6UR., Giese KP; Department of Basic and Clinical Neuroscience, Institute of Psychiatry, Psychology and Neuroscience, King's College London, Maurice Wohl Clinical Neuroscience Institute, London SE5 9RT, United Kingdom., Basson MA; Centre for Craniofacial and Regenerative Biology, Guy's Hospital, King's College London, SE1 9RT.; Department of Clinical and Biomedical Sciences, University of Exeter Medical School, Hatherly Laboratories, Prince of Wales Road, University of Exeter, Exeter, EX4 4PS, UK.
Source: BioRxiv : the preprint server for biology [bioRxiv] 2025 Dec 23. Date of Electronic Publication: 2025 Dec 23.
Publication Type: Journal Article; Preprint
Journal Info: Country of Publication: United States NLM ID: 101680187 Publication Model: Electronic Cited Medium: Internet ISSN: 2692-8205 (Electronic) Linking ISSN: 26928205 NLM ISO Abbreviation: bioRxiv Subsets: PubMed not MEDLINE
Database: MEDLINE Ultimate
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  Data: Inhibition of histone lysine demethylase restores learning and memory in aged mice.
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  Data: <searchLink fieldCode="AU" term="%22Bhatt+SU%22">Bhatt SU</searchLink>; Centre for Craniofacial and Regenerative Biology, Guy's Hospital, King's College London, SE1 9RT.<br /><searchLink fieldCode="AU" term="%22MacBean+L%22">MacBean L</searchLink>; Department of Clinical and Biomedical Sciences, University of Exeter Medical School, Hatherly Laboratories, Prince of Wales Road, University of Exeter, Exeter, EX4 4PS, UK.<br /><searchLink fieldCode="AU" term="%22Kramár+E%22">Kramár E</searchLink>; Department of Neurobiology and Behavior, School of Biological Sciences, University of California Irvine, Irvine, California, California 92697.<br /><searchLink fieldCode="AU" term="%22Pérez-Sisqués+L%22">Pérez-Sisqués L</searchLink>; MRC Centre for Neurodevelopmental Disorders, New Hunt's House, King's College London, London SE1 1UL, UK.<br /><searchLink fieldCode="AU" term="%22Smethurst+P%22">Smethurst P</searchLink>; MSD, R&D Innovation Centre, 120 Moorgate, London, EC2M 6UR.<br /><searchLink fieldCode="AU" term="%22Robb+JL%22">Robb JL</searchLink>; Department of Clinical and Biomedical Sciences, University of Exeter Medical School, Hatherly Laboratories, Prince of Wales Road, University of Exeter, Exeter, EX4 4PS, UK.<br /><searchLink fieldCode="AU" term="%22Jindal+N%22">Jindal N</searchLink>; Department of Clinical and Biomedical Sciences, University of Exeter Medical School, Hatherly Laboratories, Prince of Wales Road, University of Exeter, Exeter, EX4 4PS, UK.<br /><searchLink fieldCode="AU" term="%22Fetterly+TL%22">Fetterly TL</searchLink>; Department of Neurobiology and Behavior, School of Biological Sciences, University of California Irvine, Irvine, California, California 92697.<br /><searchLink fieldCode="AU" term="%22Graham+A%22">Graham A</searchLink>; Centre for Craniofacial and Regenerative Biology, Guy's Hospital, King's College London, SE1 9RT.<br /><searchLink fieldCode="AU" term="%22Wood+MA%22">Wood MA</searchLink>; Department of Neurobiology and Behavior, School of Biological Sciences, University of California Irvine, Irvine, California, California 92697.<br /><searchLink fieldCode="AU" term="%22Gillotin+S%22">Gillotin S</searchLink>; MSD, R&D Innovation Centre, 120 Moorgate, London, EC2M 6UR.<br /><searchLink fieldCode="AU" term="%22Giese+KP%22">Giese KP</searchLink>; Department of Basic and Clinical Neuroscience, Institute of Psychiatry, Psychology and Neuroscience, King's College London, Maurice Wohl Clinical Neuroscience Institute, London SE5 9RT, United Kingdom.<br /><searchLink fieldCode="AU" term="%22Basson+MA%22">Basson MA</searchLink>; Centre for Craniofacial and Regenerative Biology, Guy's Hospital, King's College London, SE1 9RT.; Department of Clinical and Biomedical Sciences, University of Exeter Medical School, Hatherly Laboratories, Prince of Wales Road, University of Exeter, Exeter, EX4 4PS, UK.
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  Data: <searchLink fieldCode="JN" term="%22101680187%22">BioRxiv : the preprint server for biology</searchLink> [bioRxiv] 2025 Dec 23. <i>Date of Electronic Publication: </i>2025 Dec 23.
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  Data: <i>Country of Publication: </i>United States <i>NLM ID: </i>101680187 <i>Publication Model: </i>Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>2692-8205 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2226928205%22">26928205 </searchLink><i>NLM ISO Abbreviation: </i>bioRxiv <i>Subsets: </i>PubMed not MEDLINE
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              Text: 2025 Dec 23
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