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Agomelatine 3D-printed microneedles as a potential drug delivery system for the treatment of depression.

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Title: Agomelatine 3D-printed microneedles as a potential drug delivery system for the treatment of depression.
Authors: Wojtyłko M; 3D Printing Division, Chair and Department of Pharmaceutical Technology, Poznan University of Medical Sciences, 3 Rokietnicka Street, 60-806 Poznań, Poland; Doctoral School, Poznan University of Medical Sciences, 70 Bukowska Street, 60-812 Poznań, Poland., Osmałek T; Chair and Department of Pharmaceutical Technology, Poznan University of Medical Sciences, 3 Rokietnicka Street, 60-806 Poznań, Poland. Electronic address: tosmalek@ump.edu.pl., Kuczko W; Institute of Materials Technology, Faculty of Mechanical Engineering, Poznan University of Technology, 3 Piotrowo Street, 60-965 Poznań, Poland., Wichniarek R; Institute of Materials Technology, Faculty of Mechanical Engineering, Poznan University of Technology, 3 Piotrowo Street, 60-965 Poznań, Poland., Nowicka AB; Institute of Materials Research and Quantum Engineering, The Faculty of Materials Engineering and Technical Physics, Poznan University of Technology, 3 Piotrowo Street, 60-965 Poznań, Poland., Szybowicz M; Institute of Materials Research and Quantum Engineering, The Faculty of Materials Engineering and Technical Physics, Poznan University of Technology, 3 Piotrowo Street, 60-965 Poznań, Poland., Mlynarczyk DT; Chair and Department of Chemical Technology of Drugs, Poznan University of Medical Sciences, 3 Rokietnicka Street, 60-806 Poznań, Poland., Froelich A; 3D Printing Division, Chair and Department of Pharmaceutical Technology, Poznan University of Medical Sciences, 3 Rokietnicka Street, 60-806 Poznań, Poland., Jadach B; Division of Industrial Pharmacy, Chair and Department of Pharmaceutical Technology, Poznan University of Medical Sciences, 3 Rokietnicka Street, 60-806 Poznań, Poland., Kordyl O; 3D Printing Division, Chair and Department of Pharmaceutical Technology, Poznan University of Medical Sciences, 3 Rokietnicka Street, 60-806 Poznań, Poland., Budnik I; Chair and Department of Pharmaceutical Technology, Poznan University of Medical Sciences, 3 Rokietnicka Street, 60-806 Poznań, Poland., Białek A; Student's Research Group of Pharmaceutical Technology, The Student Scientific Society of Poznan University of Medical Sciences, 5 Rokietnicka Street, 60-806 Poznań, Poland., Krysztofiak J; Student's Research Group of Pharmaceutical Technology, The Student Scientific Society of Poznan University of Medical Sciences, 5 Rokietnicka Street, 60-806 Poznań, Poland., Michniak-Kohn B; Center for Dermal Research and Ernest Mario School of Pharmacy, Rutgers, The State University of New Jersey, Piscataway, NJ 08854, USA., Budna-Tukan J; Department of Immunology, Poznan University of Medical Sciences, 10 Rokietnicka Street, 60-806 Poznan, Poland; Department of Anatomy and Histology, Collegium Medicum, University of Zielona Gora, 65-046 Zielona Gora, Poland., Miklaszewski A; Institute of Materials Science and Engineering, Faculty of Materials Engineering and Technical Physics, Poznan University of Technology, 24 Jana Pawła II Street, 60-965 Poznanń, Poland., Lamprou DA; School of Pharmacy, Queen's University Belfast, Belfast BT9 7BL, UK. Electronic address: d.lamprou@qub.ac.uk.
Source: International journal of pharmaceutics [Int J Pharm] 2026 Feb 10; Vol. 690, pp. 126572. Date of Electronic Publication: 2026 Jan 05.
Publication Type: Journal Article
Journal Info: Publisher: Elsevier/North-Holland Biomedical Press Country of Publication: Netherlands NLM ID: 7804127 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1873-3476 (Electronic) Linking ISSN: 03785173 NLM ISO Abbreviation: Int J Pharm Subsets: MEDLINE
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  Data: <searchLink fieldCode="AU" term="%22Wojtyłko+M%22">Wojtyłko M</searchLink>; 3D Printing Division, Chair and Department of Pharmaceutical Technology, Poznan University of Medical Sciences, 3 Rokietnicka Street, 60-806 Poznań, Poland; Doctoral School, Poznan University of Medical Sciences, 70 Bukowska Street, 60-812 Poznań, Poland.<br /><searchLink fieldCode="AU" term="%22Osmałek+T%22">Osmałek T</searchLink>; Chair and Department of Pharmaceutical Technology, Poznan University of Medical Sciences, 3 Rokietnicka Street, 60-806 Poznań, Poland. Electronic address: tosmalek@ump.edu.pl.<br /><searchLink fieldCode="AU" term="%22Kuczko+W%22">Kuczko W</searchLink>; Institute of Materials Technology, Faculty of Mechanical Engineering, Poznan University of Technology, 3 Piotrowo Street, 60-965 Poznań, Poland.<br /><searchLink fieldCode="AU" term="%22Wichniarek+R%22">Wichniarek R</searchLink>; Institute of Materials Technology, Faculty of Mechanical Engineering, Poznan University of Technology, 3 Piotrowo Street, 60-965 Poznań, Poland.<br /><searchLink fieldCode="AU" term="%22Nowicka+AB%22">Nowicka AB</searchLink>; Institute of Materials Research and Quantum Engineering, The Faculty of Materials Engineering and Technical Physics, Poznan University of Technology, 3 Piotrowo Street, 60-965 Poznań, Poland.<br /><searchLink fieldCode="AU" term="%22Szybowicz+M%22">Szybowicz M</searchLink>; Institute of Materials Research and Quantum Engineering, The Faculty of Materials Engineering and Technical Physics, Poznan University of Technology, 3 Piotrowo Street, 60-965 Poznań, Poland.<br /><searchLink fieldCode="AU" term="%22Mlynarczyk+DT%22">Mlynarczyk DT</searchLink>; Chair and Department of Chemical Technology of Drugs, Poznan University of Medical Sciences, 3 Rokietnicka Street, 60-806 Poznań, Poland.<br /><searchLink fieldCode="AU" term="%22Froelich+A%22">Froelich A</searchLink>; 3D Printing Division, Chair and Department of Pharmaceutical Technology, Poznan University of Medical Sciences, 3 Rokietnicka Street, 60-806 Poznań, Poland.<br /><searchLink fieldCode="AU" term="%22Jadach+B%22">Jadach B</searchLink>; Division of Industrial Pharmacy, Chair and Department of Pharmaceutical Technology, Poznan University of Medical Sciences, 3 Rokietnicka Street, 60-806 Poznań, Poland.<br /><searchLink fieldCode="AU" term="%22Kordyl+O%22">Kordyl O</searchLink>; 3D Printing Division, Chair and Department of Pharmaceutical Technology, Poznan University of Medical Sciences, 3 Rokietnicka Street, 60-806 Poznań, Poland.<br /><searchLink fieldCode="AU" term="%22Budnik+I%22">Budnik I</searchLink>; Chair and Department of Pharmaceutical Technology, Poznan University of Medical Sciences, 3 Rokietnicka Street, 60-806 Poznań, Poland.<br /><searchLink fieldCode="AU" term="%22Białek+A%22">Białek A</searchLink>; Student's Research Group of Pharmaceutical Technology, The Student Scientific Society of Poznan University of Medical Sciences, 5 Rokietnicka Street, 60-806 Poznań, Poland.<br /><searchLink fieldCode="AU" term="%22Krysztofiak+J%22">Krysztofiak J</searchLink>; Student's Research Group of Pharmaceutical Technology, The Student Scientific Society of Poznan University of Medical Sciences, 5 Rokietnicka Street, 60-806 Poznań, Poland.<br /><searchLink fieldCode="AU" term="%22Michniak-Kohn+B%22">Michniak-Kohn B</searchLink>; Center for Dermal Research and Ernest Mario School of Pharmacy, Rutgers, The State University of New Jersey, Piscataway, NJ 08854, USA.<br /><searchLink fieldCode="AU" term="%22Budna-Tukan+J%22">Budna-Tukan J</searchLink>; Department of Immunology, Poznan University of Medical Sciences, 10 Rokietnicka Street, 60-806 Poznan, Poland; Department of Anatomy and Histology, Collegium Medicum, University of Zielona Gora, 65-046 Zielona Gora, Poland.<br /><searchLink fieldCode="AU" term="%22Miklaszewski+A%22">Miklaszewski A</searchLink>; Institute of Materials Science and Engineering, Faculty of Materials Engineering and Technical Physics, Poznan University of Technology, 24 Jana Pawła II Street, 60-965 Poznanń, Poland.<br /><searchLink fieldCode="AU" term="%22Lamprou+DA%22">Lamprou DA</searchLink>; School of Pharmacy, Queen's University Belfast, Belfast BT9 7BL, UK. Electronic address: d.lamprou@qub.ac.uk.
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  Data: <searchLink fieldCode="JN" term="%227804127%22">International journal of pharmaceutics</searchLink> [Int J Pharm] 2026 Feb 10; Vol. 690, pp. 126572. <i>Date of Electronic Publication: </i>2026 Jan 05.
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