Genomic and transcriptomic analyses of melanoma in Japanese patients reveal candidate biomarkers for immune checkpoint inhibitor responders.

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Title: Genomic and transcriptomic analyses of melanoma in Japanese patients reveal candidate biomarkers for immune checkpoint inhibitor responders.
Authors: Kimura T; Department of Dermatology and Plastic Surgery, Faculty of Life Sciences, Kumamoto University, Kumamoto, Japan., Tanaka N; Cancer Precision Medicine Center, Japanese Foundation for Cancer Research, Tokyo, Japan., Maekawa T; Department of Dermatology, Jichi Medical University, Tochigi, Japan., Kiniwa Y; Department of Dermatology, Shinshu University School of Medicine, Matsumoto, Japan., Okuyama R; Department of Dermatology, Shinshu University School of Medicine, Matsumoto, Japan., Asai J; Department of Dermatology, Graduate School of Medical Science, Kyoto Prefectural University of Medicine, Kyoto, Japan., Matsushita S; Department of Dermato-Oncology, NHO Kagoshima Medical Center, Kagoshima, Japan., Uchi H; Department of Dermato-Oncology, National Hospital Organization Kyushu Cancer Center, Fukuoka, Japan., Kato H; Department of Geriatric and Environmental Dermatology, Nagoya City University Graduate School of Medical Sciences, Nagoya, Japan., Nagase K; Division of Dermatology, Department of Internal Medicine, Faculty of Medicine, Saga University, Saga, Japan., Kobayashi A; Department of Dermatology, Graduate School of Medicine, Osaka Metropolitan University, Osaka, Japan., Tanemura A; Department of Dermatology, Graduate School of Medicine, Osaka University, Osaka, Japan., Fujimura T; Department of Dermatology, Tohoku University Graduate School of Medicine, Sendai, Japan., Fujisawa Y; Department of Dermatology, University of Tsukuba, Tsukuba, Japan., Kunimoto K; Department of Dermatology, Wakayama Medical University Graduate School of Medicine, Wakayama, Japan., Ito T; Department of Dermatology, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan., Mori S; Department of Dermatology, Nagoya University Graduate School of Medicine, Nagoya, Japan., Yoshino K; Department of Dermatology, Tokyo Metropolitan Komagome Hospital, Tokyo, Japan., Yamazaki N; Department of Dermatologic Oncology, National Cancer Center Hospital, Tokyo, Japan., Yano H; Department of Tumor Pathology, Graduate School of Health Sciences, Faculty of Life Sciences, Kumamoto University, Kumamoto, Japan.; Department of Cell Pathology, Graduate School of Medical Sciences, Faculty of Life Sciences, Kumamoto University, Kumamoto, Japan., Komohara Y; Department of Cell Pathology, Graduate School of Medical Sciences, Faculty of Life Sciences, Kumamoto University, Kumamoto, Japan., Noda T; Cancer Institute, JFCR, Tokyo, Japan., Kiyotani K; Cancer Precision Medicine Center, Japanese Foundation for Cancer Research, Tokyo, Japan. k-kiyotani@nibiohn.go.jp.; Laboratory of Immunogenomics, Center for Intractable Diseases and ImmunoGenomics (CiDIG), National Institute of Biomedical Innovation, Health and Nutrition (NIBIOHN), Osaka, Japan. k-kiyotani@nibiohn.go.jp., Mori S; Cancer Precision Medicine Center, Japanese Foundation for Cancer Research, Tokyo, Japan. seiichi.mori@jfcr.or.jp.; Department of Genetic Diagnosis, Cancer Institute Hospital, JFCR, Tokyo, Japan. seiichi.mori@jfcr.or.jp., Fukushima S; Department of Dermatology and Plastic Surgery, Faculty of Life Sciences, Kumamoto University, Kumamoto, Japan. s_fukushima@kumamoto-u.ac.jp.
Source: Communications medicine [Commun Med (Lond)] 2026 Jan 07; Vol. 6 (1), pp. 78. Date of Electronic Publication: 2026 Jan 07.
Publication Type: Journal Article
Journal Info: Publisher: Nature Portfolio Country of Publication: England NLM ID: 9918250414506676 Publication Model: Electronic Cited Medium: Internet ISSN: 2730-664X (Electronic) Linking ISSN: 2730664X NLM ISO Abbreviation: Commun Med (Lond) Subsets: PubMed not MEDLINE
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  Data: Genomic and transcriptomic analyses of melanoma in Japanese patients reveal candidate biomarkers for immune checkpoint inhibitor responders.
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  Data: <searchLink fieldCode="AU" term="%22Kimura+T%22">Kimura T</searchLink>; Department of Dermatology and Plastic Surgery, Faculty of Life Sciences, Kumamoto University, Kumamoto, Japan.<br /><searchLink fieldCode="AU" term="%22Tanaka+N%22">Tanaka N</searchLink>; Cancer Precision Medicine Center, Japanese Foundation for Cancer Research, Tokyo, Japan.<br /><searchLink fieldCode="AU" term="%22Maekawa+T%22">Maekawa T</searchLink>; Department of Dermatology, Jichi Medical University, Tochigi, Japan.<br /><searchLink fieldCode="AU" term="%22Kiniwa+Y%22">Kiniwa Y</searchLink>; Department of Dermatology, Shinshu University School of Medicine, Matsumoto, Japan.<br /><searchLink fieldCode="AU" term="%22Okuyama+R%22">Okuyama R</searchLink>; Department of Dermatology, Shinshu University School of Medicine, Matsumoto, Japan.<br /><searchLink fieldCode="AU" term="%22Asai+J%22">Asai J</searchLink>; Department of Dermatology, Graduate School of Medical Science, Kyoto Prefectural University of Medicine, Kyoto, Japan.<br /><searchLink fieldCode="AU" term="%22Matsushita+S%22">Matsushita S</searchLink>; Department of Dermato-Oncology, NHO Kagoshima Medical Center, Kagoshima, Japan.<br /><searchLink fieldCode="AU" term="%22Uchi+H%22">Uchi H</searchLink>; Department of Dermato-Oncology, National Hospital Organization Kyushu Cancer Center, Fukuoka, Japan.<br /><searchLink fieldCode="AU" term="%22Kato+H%22">Kato H</searchLink>; Department of Geriatric and Environmental Dermatology, Nagoya City University Graduate School of Medical Sciences, Nagoya, Japan.<br /><searchLink fieldCode="AU" term="%22Nagase+K%22">Nagase K</searchLink>; Division of Dermatology, Department of Internal Medicine, Faculty of Medicine, Saga University, Saga, Japan.<br /><searchLink fieldCode="AU" term="%22Kobayashi+A%22">Kobayashi A</searchLink>; Department of Dermatology, Graduate School of Medicine, Osaka Metropolitan University, Osaka, Japan.<br /><searchLink fieldCode="AU" term="%22Tanemura+A%22">Tanemura A</searchLink>; Department of Dermatology, Graduate School of Medicine, Osaka University, Osaka, Japan.<br /><searchLink fieldCode="AU" term="%22Fujimura+T%22">Fujimura T</searchLink>; Department of Dermatology, Tohoku University Graduate School of Medicine, Sendai, Japan.<br /><searchLink fieldCode="AU" term="%22Fujisawa+Y%22">Fujisawa Y</searchLink>; Department of Dermatology, University of Tsukuba, Tsukuba, Japan.<br /><searchLink fieldCode="AU" term="%22Kunimoto+K%22">Kunimoto K</searchLink>; Department of Dermatology, Wakayama Medical University Graduate School of Medicine, Wakayama, Japan.<br /><searchLink fieldCode="AU" term="%22Ito+T%22">Ito T</searchLink>; Department of Dermatology, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan.<br /><searchLink fieldCode="AU" term="%22Mori+S%22">Mori S</searchLink>; Department of Dermatology, Nagoya University Graduate School of Medicine, Nagoya, Japan.<br /><searchLink fieldCode="AU" term="%22Yoshino+K%22">Yoshino K</searchLink>; Department of Dermatology, Tokyo Metropolitan Komagome Hospital, Tokyo, Japan.<br /><searchLink fieldCode="AU" term="%22Yamazaki+N%22">Yamazaki N</searchLink>; Department of Dermatologic Oncology, National Cancer Center Hospital, Tokyo, Japan.<br /><searchLink fieldCode="AU" term="%22Yano+H%22">Yano H</searchLink>; Department of Tumor Pathology, Graduate School of Health Sciences, Faculty of Life Sciences, Kumamoto University, Kumamoto, Japan.; Department of Cell Pathology, Graduate School of Medical Sciences, Faculty of Life Sciences, Kumamoto University, Kumamoto, Japan.<br /><searchLink fieldCode="AU" term="%22Komohara+Y%22">Komohara Y</searchLink>; Department of Cell Pathology, Graduate School of Medical Sciences, Faculty of Life Sciences, Kumamoto University, Kumamoto, Japan.<br /><searchLink fieldCode="AU" term="%22Noda+T%22">Noda T</searchLink>; Cancer Institute, JFCR, Tokyo, Japan.<br /><searchLink fieldCode="AU" term="%22Kiyotani+K%22">Kiyotani K</searchLink>; Cancer Precision Medicine Center, Japanese Foundation for Cancer Research, Tokyo, Japan. k-kiyotani@nibiohn.go.jp.; Laboratory of Immunogenomics, Center for Intractable Diseases and ImmunoGenomics (CiDIG), National Institute of Biomedical Innovation, Health and Nutrition (NIBIOHN), Osaka, Japan. k-kiyotani@nibiohn.go.jp.<br /><searchLink fieldCode="AU" term="%22Mori+S%22">Mori S</searchLink>; Cancer Precision Medicine Center, Japanese Foundation for Cancer Research, Tokyo, Japan. seiichi.mori@jfcr.or.jp.; Department of Genetic Diagnosis, Cancer Institute Hospital, JFCR, Tokyo, Japan. seiichi.mori@jfcr.or.jp.<br /><searchLink fieldCode="AU" term="%22Fukushima+S%22">Fukushima S</searchLink>; Department of Dermatology and Plastic Surgery, Faculty of Life Sciences, Kumamoto University, Kumamoto, Japan. s_fukushima@kumamoto-u.ac.jp.
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  Data: <searchLink fieldCode="JN" term="%229918250414506676%22">Communications medicine</searchLink> [Commun Med (Lond)] 2026 Jan 07; Vol. 6 (1), pp. 78. <i>Date of Electronic Publication: </i>2026 Jan 07.
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