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191Pt-labeled trithiol-Hoechst-PSMA: preliminary evaluation of conjugates designed for delivery to genomic DNA of PSMA-positive cancers.

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Title: 191Pt-labeled trithiol-Hoechst-PSMA: preliminary evaluation of conjugates designed for delivery to genomic DNA of PSMA-positive cancers.
Authors: Obata H; Department of Advanced Nuclear Medicine Sciences, National Institutes for Quantum Science and Technology (QST), 4-9-1 Anagawa, Inage-ku, Chiba, 263-8555, Japan. obata.honoka@qst.go.jp.; Department of Molecular Imaging and Theranostics, National Institutes for Quantum Science and Technology (QST), 4-9-1 Anagawa, Inage-ku, Chiba, 263-8555, Japan. obata.honoka@qst.go.jp.; Department of Radiology, Duke University Medical Center, Durham, NC, 27710, USA. obata.honoka@qst.go.jp., Tsuji AB; Department of Molecular Imaging and Theranostics, National Institutes for Quantum Science and Technology (QST), 4-9-1 Anagawa, Inage-ku, Chiba, 263-8555, Japan., Feng Y; Department of Radiology, Duke University Medical Center, Durham, NC, 27710, USA., Zheng Y; Department of Radiology, Duke University Medical Center, Durham, NC, 27710, USA., Sugyo A; Department of Molecular Imaging and Theranostics, National Institutes for Quantum Science and Technology (QST), 4-9-1 Anagawa, Inage-ku, Chiba, 263-8555, Japan., Sudo H; Department of Molecular Imaging and Theranostics, National Institutes for Quantum Science and Technology (QST), 4-9-1 Anagawa, Inage-ku, Chiba, 263-8555, Japan., Kajiwara C; Department of Molecular Imaging and Theranostics, National Institutes for Quantum Science and Technology (QST), 4-9-1 Anagawa, Inage-ku, Chiba, 263-8555, Japan., Minegishi K; Department of Advanced Nuclear Medicine Sciences, National Institutes for Quantum Science and Technology (QST), 4-9-1 Anagawa, Inage-ku, Chiba, 263-8555, Japan., Zhang MR; Department of Advanced Nuclear Medicine Sciences, National Institutes for Quantum Science and Technology (QST), 4-9-1 Anagawa, Inage-ku, Chiba, 263-8555, Japan., Zalutsky MR; Department of Radiology, Duke University Medical Center, Durham, NC, 27710, USA. michael.zalutsky@duke.edu.
Source: EJNMMI radiopharmacy and chemistry [EJNMMI Radiopharm Chem] 2026 Jan 09; Vol. 11 (1), pp. 10. Date of Electronic Publication: 2026 Jan 09.
Publication Type: Journal Article
Journal Info: Publisher: Springer Open Country of Publication: England NLM ID: 101714628 Publication Model: Electronic Cited Medium: Internet ISSN: 2365-421X (Electronic) Linking ISSN: 2365421X NLM ISO Abbreviation: EJNMMI Radiopharm Chem Subsets: PubMed not MEDLINE
Database: MEDLINE Ultimate
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  Data: <superscript>191</superscript>Pt-labeled trithiol-Hoechst-PSMA: preliminary evaluation of conjugates designed for delivery to genomic DNA of PSMA-positive cancers.
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  Data: <searchLink fieldCode="AU" term="%22Obata+H%22">Obata H</searchLink>; Department of Advanced Nuclear Medicine Sciences, National Institutes for Quantum Science and Technology (QST), 4-9-1 Anagawa, Inage-ku, Chiba, 263-8555, Japan. obata.honoka@qst.go.jp.; Department of Molecular Imaging and Theranostics, National Institutes for Quantum Science and Technology (QST), 4-9-1 Anagawa, Inage-ku, Chiba, 263-8555, Japan. obata.honoka@qst.go.jp.; Department of Radiology, Duke University Medical Center, Durham, NC, 27710, USA. obata.honoka@qst.go.jp.<br /><searchLink fieldCode="AU" term="%22Tsuji+AB%22">Tsuji AB</searchLink>; Department of Molecular Imaging and Theranostics, National Institutes for Quantum Science and Technology (QST), 4-9-1 Anagawa, Inage-ku, Chiba, 263-8555, Japan.<br /><searchLink fieldCode="AU" term="%22Feng+Y%22">Feng Y</searchLink>; Department of Radiology, Duke University Medical Center, Durham, NC, 27710, USA.<br /><searchLink fieldCode="AU" term="%22Zheng+Y%22">Zheng Y</searchLink>; Department of Radiology, Duke University Medical Center, Durham, NC, 27710, USA.<br /><searchLink fieldCode="AU" term="%22Sugyo+A%22">Sugyo A</searchLink>; Department of Molecular Imaging and Theranostics, National Institutes for Quantum Science and Technology (QST), 4-9-1 Anagawa, Inage-ku, Chiba, 263-8555, Japan.<br /><searchLink fieldCode="AU" term="%22Sudo+H%22">Sudo H</searchLink>; Department of Molecular Imaging and Theranostics, National Institutes for Quantum Science and Technology (QST), 4-9-1 Anagawa, Inage-ku, Chiba, 263-8555, Japan.<br /><searchLink fieldCode="AU" term="%22Kajiwara+C%22">Kajiwara C</searchLink>; Department of Molecular Imaging and Theranostics, National Institutes for Quantum Science and Technology (QST), 4-9-1 Anagawa, Inage-ku, Chiba, 263-8555, Japan.<br /><searchLink fieldCode="AU" term="%22Minegishi+K%22">Minegishi K</searchLink>; Department of Advanced Nuclear Medicine Sciences, National Institutes for Quantum Science and Technology (QST), 4-9-1 Anagawa, Inage-ku, Chiba, 263-8555, Japan.<br /><searchLink fieldCode="AU" term="%22Zhang+MR%22">Zhang MR</searchLink>; Department of Advanced Nuclear Medicine Sciences, National Institutes for Quantum Science and Technology (QST), 4-9-1 Anagawa, Inage-ku, Chiba, 263-8555, Japan.<br /><searchLink fieldCode="AU" term="%22Zalutsky+MR%22">Zalutsky MR</searchLink>; Department of Radiology, Duke University Medical Center, Durham, NC, 27710, USA. michael.zalutsky@duke.edu.
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  Data: <searchLink fieldCode="JN" term="%22101714628%22">EJNMMI radiopharmacy and chemistry</searchLink> [EJNMMI Radiopharm Chem] 2026 Jan 09; Vol. 11 (1), pp. 10. <i>Date of Electronic Publication: </i>2026 Jan 09.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Springer+Open%22">Springer Open </searchLink><i>Country of Publication: </i>England <i>NLM ID: </i>101714628 <i>Publication Model: </i>Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>2365-421X (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%222365421X%22">2365421X </searchLink><i>NLM ISO Abbreviation: </i>EJNMMI Radiopharm Chem <i>Subsets: </i>PubMed not MEDLINE
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        Value: 10.1186/s41181-025-00420-0
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              Text: 2026 Jan 09
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