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The Selective Bromodomain and Extra-Terminal Domain (BET) Inhibitor RVX-208 Reduces Cocaine-Seeking Behaviour and Alters Proteomic Pathways in the Nucleus Accumbens.

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Title: The Selective Bromodomain and Extra-Terminal Domain (BET) Inhibitor RVX-208 Reduces Cocaine-Seeking Behaviour and Alters Proteomic Pathways in the Nucleus Accumbens.
Authors: Sacko TJ; Department of Pharmaceutical Sciences, University of Connecticut, Storrs, Connecticut, USA.; Center for Addiction Sciences and Innovation (CASI), University of Connecticut, Storrs, Connecticut, USA.; Institute for the Brain and Cognitive Sciences (IBACS), University of Connecticut, Storrs, Connecticut, USA., Seyednejad A; Department of Pharmaceutical Sciences, University of Connecticut, Storrs, Connecticut, USA.; Center for Addiction Sciences and Innovation (CASI), University of Connecticut, Storrs, Connecticut, USA.; Institute for the Brain and Cognitive Sciences (IBACS), University of Connecticut, Storrs, Connecticut, USA., Engelhardt J; Department of Pharmaceutical Sciences, University of Connecticut, Storrs, Connecticut, USA., Sartor GC; Department of Pharmaceutical Sciences, University of Connecticut, Storrs, Connecticut, USA.; Center for Addiction Sciences and Innovation (CASI), University of Connecticut, Storrs, Connecticut, USA.; Institute for the Brain and Cognitive Sciences (IBACS), University of Connecticut, Storrs, Connecticut, USA.
Source: Addiction biology [Addict Biol] 2026 Jan; Vol. 31 (1), pp. e70121.
Publication Type: Journal Article
Journal Info: Publisher: Wiley-Blackwell Country of Publication: United States NLM ID: 9604935 Publication Model: Print Cited Medium: Internet ISSN: 1369-1600 (Electronic) Linking ISSN: 13556215 NLM ISO Abbreviation: Addict Biol Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: <searchLink fieldCode="AU" term="%22Sacko+TJ%22">Sacko TJ</searchLink>; Department of Pharmaceutical Sciences, University of Connecticut, Storrs, Connecticut, USA.; Center for Addiction Sciences and Innovation (CASI), University of Connecticut, Storrs, Connecticut, USA.; Institute for the Brain and Cognitive Sciences (IBACS), University of Connecticut, Storrs, Connecticut, USA.<br /><searchLink fieldCode="AU" term="%22Seyednejad+A%22">Seyednejad A</searchLink>; Department of Pharmaceutical Sciences, University of Connecticut, Storrs, Connecticut, USA.; Center for Addiction Sciences and Innovation (CASI), University of Connecticut, Storrs, Connecticut, USA.; Institute for the Brain and Cognitive Sciences (IBACS), University of Connecticut, Storrs, Connecticut, USA.<br /><searchLink fieldCode="AU" term="%22Engelhardt+J%22">Engelhardt J</searchLink>; Department of Pharmaceutical Sciences, University of Connecticut, Storrs, Connecticut, USA.<br /><searchLink fieldCode="AU" term="%22Sartor+GC%22">Sartor GC</searchLink>; Department of Pharmaceutical Sciences, University of Connecticut, Storrs, Connecticut, USA.; Center for Addiction Sciences and Innovation (CASI), University of Connecticut, Storrs, Connecticut, USA.; Institute for the Brain and Cognitive Sciences (IBACS), University of Connecticut, Storrs, Connecticut, USA.
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              Text: 2026 Jan
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