Conserved Neuronal-like and Secretory Programs Define the Spatial Architecture of Gastroenteropancreatic Neuroendocrine Tumors.

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Title: Conserved Neuronal-like and Secretory Programs Define the Spatial Architecture of Gastroenteropancreatic Neuroendocrine Tumors.
Authors: Karam J; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA 02115, USA.; Broad Institute of Harvard and MIT, Cambridge, MA 02142, USA., Hoffman SE; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA 02115, USA.; Broad Institute of Harvard and MIT, Cambridge, MA 02142, USA.; Harvard-MIT MD-PhD Program, Boston, MA 02115, USA., Garza A; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA 02115, USA.; Broad Institute of Harvard and MIT, Cambridge, MA 02142, USA., Gui D; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA 02115, USA.; Broad Institute of Harvard and MIT, Cambridge, MA 02142, USA., Hoffman HI; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA 02115, USA.; Broad Institute of Harvard and MIT, Cambridge, MA 02142, USA.; Harvard-MIT MD-PhD Program, Boston, MA 02115, USA., Titchen BM; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA 02115, USA.; Broad Institute of Harvard and MIT, Cambridge, MA 02142, USA.; Division of Medical Sciences PhD Program in Biological and Biomedical Sciences, Harvard University, Cambridge, MA 02138, USA., Tanaka Y; Broad Institute of Harvard and MIT, Cambridge, MA 02142, USA.; Department of Pediatric Oncology, Dana-Farber Cancer Institute, Boston, MA 02115, USA., Pimenta E; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA 02115, USA.; Broad Institute of Harvard and MIT, Cambridge, MA 02142, USA., Pappa T; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA 02115, USA.; Broad Institute of Harvard and MIT, Cambridge, MA 02142, USA.; Division of Endocrinology, Diabetes and Metabolism, Mass General Brigham , Boston, MA 02115, USA., Valderrabano L; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA 02115, USA.; Broad Institute of Harvard and MIT, Cambridge, MA 02142, USA., Bi K; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA 02115, USA.; Broad Institute of Harvard and MIT, Cambridge, MA 02142, USA., Gillani R; Broad Institute of Harvard and MIT, Cambridge, MA 02142, USA.; Department of Pediatric Oncology, Dana-Farber Cancer Institute, Boston, MA 02115, USA.; Division of Hematology/Oncology, Boston Children's Hospital, Boston, MA 02215, USA., Brais L; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA 02115, USA.; Broad Institute of Harvard and MIT, Cambridge, MA 02142, USA., Shannon E; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA 02115, USA.; Broad Institute of Harvard and MIT, Cambridge, MA 02142, USA., Hornick JL; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA 02115, USA.; Department of Pathology, Brigham and Women's Hospital, Boston, MA 02115, USA., Park J; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA 02115, USA.; Broad Institute of Harvard and MIT, Cambridge, MA 02142, USA., Chan J; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA 02115, USA., Van Allen EM; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA 02115, USA.; Broad Institute of Harvard and MIT, Cambridge, MA 02142, USA.
Source: BioRxiv : the preprint server for biology [bioRxiv] 2025 Dec 29. Date of Electronic Publication: 2025 Dec 29.
Publication Type: Journal Article; Preprint
Journal Info: Country of Publication: United States NLM ID: 101680187 Publication Model: Electronic Cited Medium: Internet ISSN: 2692-8205 (Electronic) Linking ISSN: 26928205 NLM ISO Abbreviation: bioRxiv Subsets: PubMed not MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:2692-8205
DOI:10.64898/2025.12.28.696762