Targeting of Kaposi's sarcoma-associated herpesvirus by immunotoxins directed against the viral G protein-coupled receptor, ORF74.

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Title: Targeting of Kaposi's sarcoma-associated herpesvirus by immunotoxins directed against the viral G protein-coupled receptor, ORF74.
Authors: Kildedal DF; Molecular Pharmacology, Department of Biomedical Sciences, University of Copenhagen, Copenhagen, Denmark; Synklino A/S, Copenhagen, Denmark., Drzazga AK; Molecular Pharmacology, Department of Biomedical Sciences, University of Copenhagen, Copenhagen, Denmark; Institute of Molecular and Industrial Biotechnology, Faculty of Biotechnology and Food Sciences, Lodz University of Technology, Lodz, Poland., Sharma A; Department of Microbiology, University of Washington, Seattle, WA, USA., Berg C; Molecular Pharmacology, Department of Biomedical Sciences, University of Copenhagen, Copenhagen, Denmark., Winther AN; Molecular Pharmacology, Department of Biomedical Sciences, University of Copenhagen, Copenhagen, Denmark., Krogh-Hansen L; Molecular Pharmacology, Department of Biomedical Sciences, University of Copenhagen, Copenhagen, Denmark., Gustavsson M; Molecular Pharmacology, Department of Biomedical Sciences, University of Copenhagen, Copenhagen, Denmark., Kragelund BB; Structural Biology and NMR Laboratory, Department of Biology, University of Copenhagen, Copenhagen, Denmark., Våbenø J; Helgeland Hospital Trust, Sandnessjøen, Norway., Lagunoff M; Department of Microbiology, University of Washington, Seattle, WA, USA., Tsutsumi N; Advanced Research Initiative, Institute of Integrated Research, Institute of Science Tokyo, Tokyo, Japan., Kledal TN; Synklino A/S, Copenhagen, Denmark., Jeppesen MG; Synklino A/S, Copenhagen, Denmark., Rosenkilde MM; Molecular Pharmacology, Department of Biomedical Sciences, University of Copenhagen, Copenhagen, Denmark. Electronic address: rosenkilde@sund.ku.dk.
Source: Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie [Biomed Pharmacother] 2026 Feb; Vol. 195, pp. 118797. Date of Electronic Publication: 2026 Jan 12.
Publication Type: Journal Article
Journal Info: Publisher: Editions Scientifiques Elsevier Country of Publication: France NLM ID: 8213295 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1950-6007 (Electronic) Linking ISSN: 07533322 NLM ISO Abbreviation: Biomed Pharmacother Subsets: MEDLINE
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  Data: Targeting of Kaposi's sarcoma-associated herpesvirus by immunotoxins directed against the viral G protein-coupled receptor, ORF74.
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  Data: <searchLink fieldCode="AU" term="%22Kildedal+DF%22">Kildedal DF</searchLink>; Molecular Pharmacology, Department of Biomedical Sciences, University of Copenhagen, Copenhagen, Denmark; Synklino A/S, Copenhagen, Denmark.<br /><searchLink fieldCode="AU" term="%22Drzazga+AK%22">Drzazga AK</searchLink>; Molecular Pharmacology, Department of Biomedical Sciences, University of Copenhagen, Copenhagen, Denmark; Institute of Molecular and Industrial Biotechnology, Faculty of Biotechnology and Food Sciences, Lodz University of Technology, Lodz, Poland.<br /><searchLink fieldCode="AU" term="%22Sharma+A%22">Sharma A</searchLink>; Department of Microbiology, University of Washington, Seattle, WA, USA.<br /><searchLink fieldCode="AU" term="%22Berg+C%22">Berg C</searchLink>; Molecular Pharmacology, Department of Biomedical Sciences, University of Copenhagen, Copenhagen, Denmark.<br /><searchLink fieldCode="AU" term="%22Winther+AN%22">Winther AN</searchLink>; Molecular Pharmacology, Department of Biomedical Sciences, University of Copenhagen, Copenhagen, Denmark.<br /><searchLink fieldCode="AU" term="%22Krogh-Hansen+L%22">Krogh-Hansen L</searchLink>; Molecular Pharmacology, Department of Biomedical Sciences, University of Copenhagen, Copenhagen, Denmark.<br /><searchLink fieldCode="AU" term="%22Gustavsson+M%22">Gustavsson M</searchLink>; Molecular Pharmacology, Department of Biomedical Sciences, University of Copenhagen, Copenhagen, Denmark.<br /><searchLink fieldCode="AU" term="%22Kragelund+BB%22">Kragelund BB</searchLink>; Structural Biology and NMR Laboratory, Department of Biology, University of Copenhagen, Copenhagen, Denmark.<br /><searchLink fieldCode="AU" term="%22Våbenø+J%22">Våbenø J</searchLink>; Helgeland Hospital Trust, Sandnessjøen, Norway.<br /><searchLink fieldCode="AU" term="%22Lagunoff+M%22">Lagunoff M</searchLink>; Department of Microbiology, University of Washington, Seattle, WA, USA.<br /><searchLink fieldCode="AU" term="%22Tsutsumi+N%22">Tsutsumi N</searchLink>; Advanced Research Initiative, Institute of Integrated Research, Institute of Science Tokyo, Tokyo, Japan.<br /><searchLink fieldCode="AU" term="%22Kledal+TN%22">Kledal TN</searchLink>; Synklino A/S, Copenhagen, Denmark.<br /><searchLink fieldCode="AU" term="%22Jeppesen+MG%22">Jeppesen MG</searchLink>; Synklino A/S, Copenhagen, Denmark.<br /><searchLink fieldCode="AU" term="%22Rosenkilde+MM%22">Rosenkilde MM</searchLink>; Molecular Pharmacology, Department of Biomedical Sciences, University of Copenhagen, Copenhagen, Denmark. Electronic address: rosenkilde@sund.ku.dk.
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  Data: <searchLink fieldCode="JN" term="%228213295%22">Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie</searchLink> [Biomed Pharmacother] 2026 Feb; Vol. 195, pp. 118797. <i>Date of Electronic Publication: </i>2026 Jan 12.
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