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A SET domain-containing protein and HCF-1 maintain transgenerational epigenetic memory.

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Title: A SET domain-containing protein and HCF-1 maintain transgenerational epigenetic memory.
Authors: Zeng C; Department of Biochemistry, University of Cambridge, Cambridge, CB2, United Kingdom.; The Gurdon Institute, University of Cambridge, Cambridge, CB2, United Kingdom., Furlan G; The Gurdon Institute, University of Cambridge, Cambridge, CB2, United Kingdom., Almeida MV; Department of Biochemistry, University of Cambridge, Cambridge, CB2, United Kingdom.; The Gurdon Institute, University of Cambridge, Cambridge, CB2, United Kingdom., Rueda-Silva JC; Department of Biochemistry, University of Cambridge, Cambridge, CB2, United Kingdom.; The Gurdon Institute, University of Cambridge, Cambridge, CB2, United Kingdom.; Department of Genetics, University of Cambridge, Cambridge, CB2, United Kingdom., Price J; Department of Biochemistry, University of Cambridge, Cambridge, CB2, United Kingdom.; The Gurdon Institute, University of Cambridge, Cambridge, CB2, United Kingdom., Santos-Rosa H; Department of Biochemistry, University of Cambridge, Cambridge, CB2, United Kingdom.; The Gurdon Institute, University of Cambridge, Cambridge, CB2, United Kingdom., Xu J; Department of Biochemistry, University of Cambridge, Cambridge, CB2, United Kingdom., Kuang Y; School of Life Science, University of Science and Technology of China, Hefei, Anhui, China., Socias EC; Department of Biochemistry, University of Cambridge, Cambridge, CB2, United Kingdom., Mars J; The Gurdon Institute, University of Cambridge, Cambridge, CB2, United Kingdom., Rebelo-Guiomar P; Department of Biochemistry, University of Cambridge, Cambridge, CB2, United Kingdom., Huang M; School of Life Science, University of Science and Technology of China, Hefei, Anhui, China., Guang S; School of Life Science, University of Science and Technology of China, Hefei, Anhui, China., Butter F; Institute of Molecular Biology, Mainz, Germany.; Institute of Molecular Virology and Cell Biology, Friedrich-Loeffler-Institute, Greifswald, Germany., Miska EA; Department of Biochemistry, University of Cambridge, Cambridge, CB2, United Kingdom. eam29@cam.ac.uk.; The Gurdon Institute, University of Cambridge, Cambridge, CB2, United Kingdom. eam29@cam.ac.uk.; Department of Genetics, University of Cambridge, Cambridge, CB2, United Kingdom. eam29@cam.ac.uk.; Wellcome Sanger Institute, Wellcome Trust Genome Campus, Cambridge, United Kingdom. eam29@cam.ac.uk.
Source: Nature communications [Nat Commun] 2026 Jan 09; Vol. 17 (1), pp. 1462. Date of Electronic Publication: 2026 Jan 09.
Publication Type: Journal Article
Journal Info: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE
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  Data: <searchLink fieldCode="AU" term="%22Zeng+C%22">Zeng C</searchLink>; Department of Biochemistry, University of Cambridge, Cambridge, CB2, United Kingdom.; The Gurdon Institute, University of Cambridge, Cambridge, CB2, United Kingdom.<br /><searchLink fieldCode="AU" term="%22Furlan+G%22">Furlan G</searchLink>; The Gurdon Institute, University of Cambridge, Cambridge, CB2, United Kingdom.<br /><searchLink fieldCode="AU" term="%22Almeida+MV%22">Almeida MV</searchLink>; Department of Biochemistry, University of Cambridge, Cambridge, CB2, United Kingdom.; The Gurdon Institute, University of Cambridge, Cambridge, CB2, United Kingdom.<br /><searchLink fieldCode="AU" term="%22Rueda-Silva+JC%22">Rueda-Silva JC</searchLink>; Department of Biochemistry, University of Cambridge, Cambridge, CB2, United Kingdom.; The Gurdon Institute, University of Cambridge, Cambridge, CB2, United Kingdom.; Department of Genetics, University of Cambridge, Cambridge, CB2, United Kingdom.<br /><searchLink fieldCode="AU" term="%22Price+J%22">Price J</searchLink>; Department of Biochemistry, University of Cambridge, Cambridge, CB2, United Kingdom.; The Gurdon Institute, University of Cambridge, Cambridge, CB2, United Kingdom.<br /><searchLink fieldCode="AU" term="%22Santos-Rosa+H%22">Santos-Rosa H</searchLink>; Department of Biochemistry, University of Cambridge, Cambridge, CB2, United Kingdom.; The Gurdon Institute, University of Cambridge, Cambridge, CB2, United Kingdom.<br /><searchLink fieldCode="AU" term="%22Xu+J%22">Xu J</searchLink>; Department of Biochemistry, University of Cambridge, Cambridge, CB2, United Kingdom.<br /><searchLink fieldCode="AU" term="%22Kuang+Y%22">Kuang Y</searchLink>; School of Life Science, University of Science and Technology of China, Hefei, Anhui, China.<br /><searchLink fieldCode="AU" term="%22Socias+EC%22">Socias EC</searchLink>; Department of Biochemistry, University of Cambridge, Cambridge, CB2, United Kingdom.<br /><searchLink fieldCode="AU" term="%22Mars+J%22">Mars J</searchLink>; The Gurdon Institute, University of Cambridge, Cambridge, CB2, United Kingdom.<br /><searchLink fieldCode="AU" term="%22Rebelo-Guiomar+P%22">Rebelo-Guiomar P</searchLink>; Department of Biochemistry, University of Cambridge, Cambridge, CB2, United Kingdom.<br /><searchLink fieldCode="AU" term="%22Huang+M%22">Huang M</searchLink>; School of Life Science, University of Science and Technology of China, Hefei, Anhui, China.<br /><searchLink fieldCode="AU" term="%22Guang+S%22">Guang S</searchLink>; School of Life Science, University of Science and Technology of China, Hefei, Anhui, China.<br /><searchLink fieldCode="AU" term="%22Butter+F%22">Butter F</searchLink>; Institute of Molecular Biology, Mainz, Germany.; Institute of Molecular Virology and Cell Biology, Friedrich-Loeffler-Institute, Greifswald, Germany.<br /><searchLink fieldCode="AU" term="%22Miska+EA%22">Miska EA</searchLink>; Department of Biochemistry, University of Cambridge, Cambridge, CB2, United Kingdom. eam29@cam.ac.uk.; The Gurdon Institute, University of Cambridge, Cambridge, CB2, United Kingdom. eam29@cam.ac.uk.; Department of Genetics, University of Cambridge, Cambridge, CB2, United Kingdom. eam29@cam.ac.uk.; Wellcome Sanger Institute, Wellcome Trust Genome Campus, Cambridge, United Kingdom. eam29@cam.ac.uk.
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