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Intestinal Sclerostin Deficiency Links Gut Dysbiosis to Altered Serotonin Homeostasis in Axial Spondyloarthritis.

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Title: Intestinal Sclerostin Deficiency Links Gut Dysbiosis to Altered Serotonin Homeostasis in Axial Spondyloarthritis.
Authors: Mauro D; Dipartimento di Medicina di Precisione, Università della Campania 'Luigi Vanvitelli', Naples, Italy., Bergot AS; The University of Queensland Diamantina Institute, Translational Research Institute, Brisbane, QLD, Australia., Guggino G; Dipartimento PROMISE, University of Palermo, Palermo, Italy., Salzillo A; Dipartimento di Medicina di Precisione, Università della Campania 'Luigi Vanvitelli', Naples, Italy., Forte G; Dipartimento di Medicina di Precisione, Università della Campania 'Luigi Vanvitelli', Naples, Italy., Ciancio A; Dipartimento di Medicina di Precisione, Università della Campania 'Luigi Vanvitelli', Naples, Italy., Rizzo A; Azienda Ospedaliera Ospedali Riuniti Villa Sofia-Cervello, Palermo, Italy., Raimondo S; Dipartimento di Biomedicina, Neuroscienze e Diagnostica Avanzata (Bi.N.D), Università di Palermo, Palermo, Italy., Lentini L; Azienda Ospedaliera Ospedali Riuniti Villa Sofia-Cervello, Palermo, Italy., Gandolfo S; Rheumatology Unit, Ospedale del Mare, Naples, Italy., Kim SP; Department of Orthopedics, University of Maryland School of Medicine, Baltimore, MD, USA., Wong C; Leeds Biomedical Research Centre, University of Leeds, Leeds, UK., De Marino B; Dipartimento di Medicina di Precisione, Università della Campania 'Luigi Vanvitelli', Naples, Italy., Milling S; School of Infection and Immunity, University of Glasgow, Glasgow, UK., Alessandro R; Dipartimento di Biomedicina, Neuroscienze e Diagnostica Avanzata (Bi.N.D), Università di Palermo, Palermo, Italy., Panarese I; Pathology Unit, Dipartimento di Salute Mentale, Fisica e Medicina Preventiva, Università degli Studi della Campania 'Luigi Vanvitelli', Naples, Italy., Riddle RC; Department of Orthopedics, University of Maryland School of Medicine, Baltimore, MD, USA., Zaiss MM; Department of Internal Medicine 3, Rheumatology and Immunology, Friedrich-Alexander- University Erlangen-Nürnberg (FAU) and Universitätsklinikum Erlangen, Erlangen, Germany.; Deutsches Zentrum Immuntherapie (DZI) FAU Erlangen-Nürnberg and Universitätsklinikum Erlangen, Erlangen, Germany., McGonagle D; Leeds Biomedical Research Centre, University of Leeds, Leeds, UK., Thomas R; The University of Queensland Diamantina Institute, Translational Research Institute, Brisbane, QLD, Australia., Ciccia F; Dipartimento di Medicina di Precisione, Università della Campania 'Luigi Vanvitelli', Naples, Italy. francesco.ciccia@unicampania.it.
Source: Inflammation [Inflammation] 2026 Jan 10; Vol. 49 (1), pp. 38. Date of Electronic Publication: 2026 Jan 10.
Publication Type: Journal Article
Journal Info: Publisher: Kluwer Academic/Plenum Publishers Country of Publication: United States NLM ID: 7600105 Publication Model: Electronic Cited Medium: Internet ISSN: 1573-2576 (Electronic) Linking ISSN: 03603997 NLM ISO Abbreviation: Inflammation Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Intestinal Sclerostin Deficiency Links Gut Dysbiosis to Altered Serotonin Homeostasis in Axial Spondyloarthritis.
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  Data: <searchLink fieldCode="AU" term="%22Mauro+D%22">Mauro D</searchLink>; Dipartimento di Medicina di Precisione, Università della Campania 'Luigi Vanvitelli', Naples, Italy.<br /><searchLink fieldCode="AU" term="%22Bergot+AS%22">Bergot AS</searchLink>; The University of Queensland Diamantina Institute, Translational Research Institute, Brisbane, QLD, Australia.<br /><searchLink fieldCode="AU" term="%22Guggino+G%22">Guggino G</searchLink>; Dipartimento PROMISE, University of Palermo, Palermo, Italy.<br /><searchLink fieldCode="AU" term="%22Salzillo+A%22">Salzillo A</searchLink>; Dipartimento di Medicina di Precisione, Università della Campania 'Luigi Vanvitelli', Naples, Italy.<br /><searchLink fieldCode="AU" term="%22Forte+G%22">Forte G</searchLink>; Dipartimento di Medicina di Precisione, Università della Campania 'Luigi Vanvitelli', Naples, Italy.<br /><searchLink fieldCode="AU" term="%22Ciancio+A%22">Ciancio A</searchLink>; Dipartimento di Medicina di Precisione, Università della Campania 'Luigi Vanvitelli', Naples, Italy.<br /><searchLink fieldCode="AU" term="%22Rizzo+A%22">Rizzo A</searchLink>; Azienda Ospedaliera Ospedali Riuniti Villa Sofia-Cervello, Palermo, Italy.<br /><searchLink fieldCode="AU" term="%22Raimondo+S%22">Raimondo S</searchLink>; Dipartimento di Biomedicina, Neuroscienze e Diagnostica Avanzata (Bi.N.D), Università di Palermo, Palermo, Italy.<br /><searchLink fieldCode="AU" term="%22Lentini+L%22">Lentini L</searchLink>; Azienda Ospedaliera Ospedali Riuniti Villa Sofia-Cervello, Palermo, Italy.<br /><searchLink fieldCode="AU" term="%22Gandolfo+S%22">Gandolfo S</searchLink>; Rheumatology Unit, Ospedale del Mare, Naples, Italy.<br /><searchLink fieldCode="AU" term="%22Kim+SP%22">Kim SP</searchLink>; Department of Orthopedics, University of Maryland School of Medicine, Baltimore, MD, USA.<br /><searchLink fieldCode="AU" term="%22Wong+C%22">Wong C</searchLink>; Leeds Biomedical Research Centre, University of Leeds, Leeds, UK.<br /><searchLink fieldCode="AU" term="%22De+Marino+B%22">De Marino B</searchLink>; Dipartimento di Medicina di Precisione, Università della Campania 'Luigi Vanvitelli', Naples, Italy.<br /><searchLink fieldCode="AU" term="%22Milling+S%22">Milling S</searchLink>; School of Infection and Immunity, University of Glasgow, Glasgow, UK.<br /><searchLink fieldCode="AU" term="%22Alessandro+R%22">Alessandro R</searchLink>; Dipartimento di Biomedicina, Neuroscienze e Diagnostica Avanzata (Bi.N.D), Università di Palermo, Palermo, Italy.<br /><searchLink fieldCode="AU" term="%22Panarese+I%22">Panarese I</searchLink>; Pathology Unit, Dipartimento di Salute Mentale, Fisica e Medicina Preventiva, Università degli Studi della Campania 'Luigi Vanvitelli', Naples, Italy.<br /><searchLink fieldCode="AU" term="%22Riddle+RC%22">Riddle RC</searchLink>; Department of Orthopedics, University of Maryland School of Medicine, Baltimore, MD, USA.<br /><searchLink fieldCode="AU" term="%22Zaiss+MM%22">Zaiss MM</searchLink>; Department of Internal Medicine 3, Rheumatology and Immunology, Friedrich-Alexander- University Erlangen-Nürnberg (FAU) and Universitätsklinikum Erlangen, Erlangen, Germany.; Deutsches Zentrum Immuntherapie (DZI) FAU Erlangen-Nürnberg and Universitätsklinikum Erlangen, Erlangen, Germany.<br /><searchLink fieldCode="AU" term="%22McGonagle+D%22">McGonagle D</searchLink>; Leeds Biomedical Research Centre, University of Leeds, Leeds, UK.<br /><searchLink fieldCode="AU" term="%22Thomas+R%22">Thomas R</searchLink>; The University of Queensland Diamantina Institute, Translational Research Institute, Brisbane, QLD, Australia.<br /><searchLink fieldCode="AU" term="%22Ciccia+F%22">Ciccia F</searchLink>; Dipartimento di Medicina di Precisione, Università della Campania 'Luigi Vanvitelli', Naples, Italy. francesco.ciccia@unicampania.it.
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  Data: <searchLink fieldCode="JN" term="%227600105%22">Inflammation</searchLink> [Inflammation] 2026 Jan 10; Vol. 49 (1), pp. 38. <i>Date of Electronic Publication: </i>2026 Jan 10.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Kluwer+Academic%2FPlenum+Publishers%22">Kluwer Academic/Plenum Publishers </searchLink><i>Country of Publication: </i>United States <i>NLM ID: </i>7600105 <i>Publication Model: </i>Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1573-2576 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2203603997%22">03603997 </searchLink><i>NLM ISO Abbreviation: </i>Inflammation <i>Subsets: </i>MEDLINE
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      – TitleFull: Intestinal Sclerostin Deficiency Links Gut Dysbiosis to Altered Serotonin Homeostasis in Axial Spondyloarthritis.
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