Higher-Throughput Proteome Profiling Enabled by Parallelized Pre-Accumulation and Optimized Ion Processing in the Orbitrap Astral Zoom Mass Spectrometer.

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Title: Higher-Throughput Proteome Profiling Enabled by Parallelized Pre-Accumulation and Optimized Ion Processing in the Orbitrap Astral Zoom Mass Spectrometer.
Authors: Guzman UH; Department of Cellular and Molecular Medicine, Novo Nordisk Foundation Center for Protein Research, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark., Rykær M; Department of Cellular and Molecular Medicine, Novo Nordisk Foundation Center for Protein Research, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark., Hendriks IA; Department of Cellular and Molecular Medicine, Novo Nordisk Foundation Center for Protein Research, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark., Stewart H; Thermo Fisher Scientific, Bremen, Germany., Denisov E; Thermo Fisher Scientific, Bremen, Germany., Hagedorn B; Thermo Fisher Scientific, Bremen, Germany., Petzoldt J; Thermo Fisher Scientific, Bremen, Germany., Kreutzmann A; Thermo Fisher Scientific, Bremen, Germany., Mueller Y; Thermo Fisher Scientific, Bremen, Germany., Arrey TN; Thermo Fisher Scientific, Bremen, Germany., Colonius I; Thermo Fisher Scientific, Bremen, Germany., Østergaard O; Department of Cellular and Molecular Medicine, Novo Nordisk Foundation Center for Protein Research, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark., Koenig C; Department of Cellular and Molecular Medicine, Novo Nordisk Foundation Center for Protein Research, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark., Kraegenbring J; Thermo Fisher Scientific, Bremen, Germany., Fort KL; Thermo Fisher Scientific, Bremen, Germany., Couzijn E; Thermo Fisher Scientific, Bremen, Germany., Hauschild JP; Thermo Fisher Scientific, Bremen, Germany., Hermanson D; Thermo Fisher Scientific, Bremen, Germany., Zabrouskov V; Thermo Fisher Scientific, Bremen, Germany., Hock C; Thermo Fisher Scientific, Bremen, Germany., Damoc E; Thermo Fisher Scientific, Bremen, Germany., Olsen JV; Department of Cellular and Molecular Medicine, Novo Nordisk Foundation Center for Protein Research, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark. Electronic address: jesper.olsen@cpr.ku.dk.
Source: Molecular & cellular proteomics : MCP [Mol Cell Proteomics] 2026 Feb; Vol. 25 (2), pp. 101504. Date of Electronic Publication: 2026 Jan 09.
Publication Type: Journal Article
Journal Info: Publisher: Elsevier Inc. on behalf of American Society for Biochemistry and Molecular Biology Country of Publication: United States NLM ID: 101125647 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1535-9484 (Electronic) Linking ISSN: 15359476 NLM ISO Abbreviation: Mol Cell Proteomics Subsets: MEDLINE
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  Data: Higher-Throughput Proteome Profiling Enabled by Parallelized Pre-Accumulation and Optimized Ion Processing in the Orbitrap Astral Zoom Mass Spectrometer.
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  Data: <searchLink fieldCode="AU" term="%22Guzman+UH%22">Guzman UH</searchLink>; Department of Cellular and Molecular Medicine, Novo Nordisk Foundation Center for Protein Research, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.<br /><searchLink fieldCode="AU" term="%22Rykær+M%22">Rykær M</searchLink>; Department of Cellular and Molecular Medicine, Novo Nordisk Foundation Center for Protein Research, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.<br /><searchLink fieldCode="AU" term="%22Hendriks+IA%22">Hendriks IA</searchLink>; Department of Cellular and Molecular Medicine, Novo Nordisk Foundation Center for Protein Research, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.<br /><searchLink fieldCode="AU" term="%22Stewart+H%22">Stewart H</searchLink>; Thermo Fisher Scientific, Bremen, Germany.<br /><searchLink fieldCode="AU" term="%22Denisov+E%22">Denisov E</searchLink>; Thermo Fisher Scientific, Bremen, Germany.<br /><searchLink fieldCode="AU" term="%22Hagedorn+B%22">Hagedorn B</searchLink>; Thermo Fisher Scientific, Bremen, Germany.<br /><searchLink fieldCode="AU" term="%22Petzoldt+J%22">Petzoldt J</searchLink>; Thermo Fisher Scientific, Bremen, Germany.<br /><searchLink fieldCode="AU" term="%22Kreutzmann+A%22">Kreutzmann A</searchLink>; Thermo Fisher Scientific, Bremen, Germany.<br /><searchLink fieldCode="AU" term="%22Mueller+Y%22">Mueller Y</searchLink>; Thermo Fisher Scientific, Bremen, Germany.<br /><searchLink fieldCode="AU" term="%22Arrey+TN%22">Arrey TN</searchLink>; Thermo Fisher Scientific, Bremen, Germany.<br /><searchLink fieldCode="AU" term="%22Colonius+I%22">Colonius I</searchLink>; Thermo Fisher Scientific, Bremen, Germany.<br /><searchLink fieldCode="AU" term="%22Østergaard+O%22">Østergaard O</searchLink>; Department of Cellular and Molecular Medicine, Novo Nordisk Foundation Center for Protein Research, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.<br /><searchLink fieldCode="AU" term="%22Koenig+C%22">Koenig C</searchLink>; Department of Cellular and Molecular Medicine, Novo Nordisk Foundation Center for Protein Research, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.<br /><searchLink fieldCode="AU" term="%22Kraegenbring+J%22">Kraegenbring J</searchLink>; Thermo Fisher Scientific, Bremen, Germany.<br /><searchLink fieldCode="AU" term="%22Fort+KL%22">Fort KL</searchLink>; Thermo Fisher Scientific, Bremen, Germany.<br /><searchLink fieldCode="AU" term="%22Couzijn+E%22">Couzijn E</searchLink>; Thermo Fisher Scientific, Bremen, Germany.<br /><searchLink fieldCode="AU" term="%22Hauschild+JP%22">Hauschild JP</searchLink>; Thermo Fisher Scientific, Bremen, Germany.<br /><searchLink fieldCode="AU" term="%22Hermanson+D%22">Hermanson D</searchLink>; Thermo Fisher Scientific, Bremen, Germany.<br /><searchLink fieldCode="AU" term="%22Zabrouskov+V%22">Zabrouskov V</searchLink>; Thermo Fisher Scientific, Bremen, Germany.<br /><searchLink fieldCode="AU" term="%22Hock+C%22">Hock C</searchLink>; Thermo Fisher Scientific, Bremen, Germany.<br /><searchLink fieldCode="AU" term="%22Damoc+E%22">Damoc E</searchLink>; Thermo Fisher Scientific, Bremen, Germany.<br /><searchLink fieldCode="AU" term="%22Olsen+JV%22">Olsen JV</searchLink>; Department of Cellular and Molecular Medicine, Novo Nordisk Foundation Center for Protein Research, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark. Electronic address: jesper.olsen@cpr.ku.dk.
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  Data: <searchLink fieldCode="JN" term="%22101125647%22">Molecular & cellular proteomics : MCP</searchLink> [Mol Cell Proteomics] 2026 Feb; Vol. 25 (2), pp. 101504. <i>Date of Electronic Publication: </i>2026 Jan 09.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Elsevier+Inc%2E+on+behalf+of+American+Society+for+Biochemistry+and+Molecular+Biology%22">Elsevier Inc. on behalf of American Society for Biochemistry and Molecular Biology </searchLink><i>Country of Publication: </i>United States <i>NLM ID: </i>101125647 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1535-9484 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2215359476%22">15359476 </searchLink><i>NLM ISO Abbreviation: </i>Mol Cell Proteomics <i>Subsets: </i>MEDLINE
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