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Hypomethylating agents alone or in combination with venetoclax in very elderly acute myeloid leukemia patients: less treatment, better care?

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Title: Hypomethylating agents alone or in combination with venetoclax in very elderly acute myeloid leukemia patients: less treatment, better care?
Authors: Tarantini F; Department of Precision and Regenerative Medicine and Ionian Area - DiMePRe-J - Azienda Ospedaliero Universitaria Consorziale Policlinico - Hematology and Stem Cell Transplantation Unit, University of Bari 'Aldo Moro', P.zza G. Cesare, 11, 70124, Bari, Italy., Contento C; Hematology and Stem Cell Transplant Unit, 'Vito Fazzi' Hospital, 73100, Lecce, Italy., Vigna E; Department of Onco-Hematology, Hematology Unit, Cosenza, Italy., Carluccio V; Hematology and Transplant Unit, Dimiccoli Hospital, 76121, Barletta, BT, Italy., Greco G; Hematology and Transplant Unit, Cardinal Panico Hospital, 73039, Tricase, Italy., Pasciolla C; U.O. Di Ematologia, IRCCS Istituto Tumori Giovanni Paolo II, Bari, Italy., Ciuffreda L; Hematology and Transplant Unit, Policlinico Foggia Ospedaliero-Universitario, Foggia, Italy., Rossi G; Hematology, Ospedale Casa Sollievo Della Sofferenza, San Giovanni Rotondo, Foggia, Italy., Urbano MA; Hematology Unit, A. Perrino Hospital, 72100, Brindisi, Italy., D'Ambrosio A; AORN S. Anna E S. Sebastiano, Caserta, Italy., Aprile L; Hematology Unit, Department of Hematology-Oncology, Moscati Hospital, 74010, Taranto, Italy., Gagliardi VP; Department of Precision and Regenerative Medicine and Ionian Area - DiMePRe-J - Azienda Ospedaliero Universitaria Consorziale Policlinico - Hematology and Stem Cell Transplantation Unit, University of Bari 'Aldo Moro', P.zza G. Cesare, 11, 70124, Bari, Italy., Delia M; Department of Precision and Regenerative Medicine and Ionian Area - DiMePRe-J - Azienda Ospedaliero Universitaria Consorziale Policlinico - Hematology and Stem Cell Transplantation Unit, University of Bari 'Aldo Moro', P.zza G. Cesare, 11, 70124, Bari, Italy., Attolico I; Department of Precision and Regenerative Medicine and Ionian Area - DiMePRe-J - Azienda Ospedaliero Universitaria Consorziale Policlinico - Hematology and Stem Cell Transplantation Unit, University of Bari 'Aldo Moro', P.zza G. Cesare, 11, 70124, Bari, Italy., Carluccio P; Department of Precision and Regenerative Medicine and Ionian Area - DiMePRe-J - Azienda Ospedaliero Universitaria Consorziale Policlinico - Hematology and Stem Cell Transplantation Unit, University of Bari 'Aldo Moro', P.zza G. Cesare, 11, 70124, Bari, Italy., Federico V; Hematology and Stem Cell Transplant Unit, 'Vito Fazzi' Hospital, 73100, Lecce, Italy., Bruzzese A; Department of Onco-Hematology, Hematology Unit, Cosenza, Italy., Di Renzo N; Hematology and Stem Cell Transplant Unit, 'Vito Fazzi' Hospital, 73100, Lecce, Italy., Gentile M; Department of Onco-Hematology, Hematology Unit, Cosenza, Italy., Tarantini G; Hematology and Transplant Unit, Dimiccoli Hospital, 76121, Barletta, BT, Italy., Mele A; Hematology and Transplant Unit, Cardinal Panico Hospital, 73039, Tricase, Italy., Guarini A; U.O. Di Ematologia, IRCCS Istituto Tumori Giovanni Paolo II, Bari, Italy., Melillo LMA; Hematology and Transplant Unit, Policlinico Foggia Ospedaliero-Universitario, Foggia, Italy., Carella AM; Hematology, Ospedale Casa Sollievo Della Sofferenza, San Giovanni Rotondo, Foggia, Italy., Pastore D; Hematology Unit, A. Perrino Hospital, 72100, Brindisi, Italy., Frigeri F; AORN S. Anna E S. Sebastiano, Caserta, Italy., Maggi A; Hematology Unit, Department of Hematology-Oncology, Moscati Hospital, 74010, Taranto, Italy., Cumbo C; Department of Precision and Regenerative Medicine and Ionian Area - DiMePRe-J - Azienda Ospedaliero Universitaria Consorziale Policlinico - Hematology and Stem Cell Transplantation Unit, University of Bari 'Aldo Moro', P.zza G. Cesare, 11, 70124, Bari, Italy., Specchia G; School of Medicine, University of Bari 'Aldo Moro', 70124, Bari, Italy., Musto P; Department of Precision and Regenerative Medicine and Ionian Area - DiMePRe-J - Azienda Ospedaliero Universitaria Consorziale Policlinico - Hematology and Stem Cell Transplantation Unit, University of Bari 'Aldo Moro', P.zza G. Cesare, 11, 70124, Bari, Italy., Albano F; Department of Precision and Regenerative Medicine and Ionian Area - DiMePRe-J - Azienda Ospedaliero Universitaria Consorziale Policlinico - Hematology and Stem Cell Transplantation Unit, University of Bari 'Aldo Moro', P.zza G. Cesare, 11, 70124, Bari, Italy. francesco.albano@uniba.it.
Source: Annals of hematology [Ann Hematol] 2026 Jan 11; Vol. 105 (1), pp. 1. Date of Electronic Publication: 2026 Jan 11.
Publication Type: Journal Article
Journal Info: Publisher: Springer Verlag Country of Publication: Germany NLM ID: 9107334 Publication Model: Electronic Cited Medium: Internet ISSN: 1432-0584 (Electronic) Linking ISSN: 09395555 NLM ISO Abbreviation: Ann Hematol Subsets: MEDLINE
Database: MEDLINE Ultimate
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An: 41521357
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  Data: Hypomethylating agents alone or in combination with venetoclax in very elderly acute myeloid leukemia patients: less treatment, better care?
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  Data: <searchLink fieldCode="AU" term="%22Tarantini+F%22">Tarantini F</searchLink>; Department of Precision and Regenerative Medicine and Ionian Area - DiMePRe-J - Azienda Ospedaliero Universitaria Consorziale Policlinico - Hematology and Stem Cell Transplantation Unit, University of Bari 'Aldo Moro', P.zza G. Cesare, 11, 70124, Bari, Italy.<br /><searchLink fieldCode="AU" term="%22Contento+C%22">Contento C</searchLink>; Hematology and Stem Cell Transplant Unit, 'Vito Fazzi' Hospital, 73100, Lecce, Italy.<br /><searchLink fieldCode="AU" term="%22Vigna+E%22">Vigna E</searchLink>; Department of Onco-Hematology, Hematology Unit, Cosenza, Italy.<br /><searchLink fieldCode="AU" term="%22Carluccio+V%22">Carluccio V</searchLink>; Hematology and Transplant Unit, Dimiccoli Hospital, 76121, Barletta, BT, Italy.<br /><searchLink fieldCode="AU" term="%22Greco+G%22">Greco G</searchLink>; Hematology and Transplant Unit, Cardinal Panico Hospital, 73039, Tricase, Italy.<br /><searchLink fieldCode="AU" term="%22Pasciolla+C%22">Pasciolla C</searchLink>; U.O. Di Ematologia, IRCCS Istituto Tumori Giovanni Paolo II, Bari, Italy.<br /><searchLink fieldCode="AU" term="%22Ciuffreda+L%22">Ciuffreda L</searchLink>; Hematology and Transplant Unit, Policlinico Foggia Ospedaliero-Universitario, Foggia, Italy.<br /><searchLink fieldCode="AU" term="%22Rossi+G%22">Rossi G</searchLink>; Hematology, Ospedale Casa Sollievo Della Sofferenza, San Giovanni Rotondo, Foggia, Italy.<br /><searchLink fieldCode="AU" term="%22Urbano+MA%22">Urbano MA</searchLink>; Hematology Unit, A. Perrino Hospital, 72100, Brindisi, Italy.<br /><searchLink fieldCode="AU" term="%22D'Ambrosio+A%22">D'Ambrosio A</searchLink>; AORN S. Anna E S. Sebastiano, Caserta, Italy.<br /><searchLink fieldCode="AU" term="%22Aprile+L%22">Aprile L</searchLink>; Hematology Unit, Department of Hematology-Oncology, Moscati Hospital, 74010, Taranto, Italy.<br /><searchLink fieldCode="AU" term="%22Gagliardi+VP%22">Gagliardi VP</searchLink>; Department of Precision and Regenerative Medicine and Ionian Area - DiMePRe-J - Azienda Ospedaliero Universitaria Consorziale Policlinico - Hematology and Stem Cell Transplantation Unit, University of Bari 'Aldo Moro', P.zza G. Cesare, 11, 70124, Bari, Italy.<br /><searchLink fieldCode="AU" term="%22Delia+M%22">Delia M</searchLink>; Department of Precision and Regenerative Medicine and Ionian Area - DiMePRe-J - Azienda Ospedaliero Universitaria Consorziale Policlinico - Hematology and Stem Cell Transplantation Unit, University of Bari 'Aldo Moro', P.zza G. Cesare, 11, 70124, Bari, Italy.<br /><searchLink fieldCode="AU" term="%22Attolico+I%22">Attolico I</searchLink>; Department of Precision and Regenerative Medicine and Ionian Area - DiMePRe-J - Azienda Ospedaliero Universitaria Consorziale Policlinico - Hematology and Stem Cell Transplantation Unit, University of Bari 'Aldo Moro', P.zza G. Cesare, 11, 70124, Bari, Italy.<br /><searchLink fieldCode="AU" term="%22Carluccio+P%22">Carluccio P</searchLink>; Department of Precision and Regenerative Medicine and Ionian Area - DiMePRe-J - Azienda Ospedaliero Universitaria Consorziale Policlinico - Hematology and Stem Cell Transplantation Unit, University of Bari 'Aldo Moro', P.zza G. Cesare, 11, 70124, Bari, Italy.<br /><searchLink fieldCode="AU" term="%22Federico+V%22">Federico V</searchLink>; Hematology and Stem Cell Transplant Unit, 'Vito Fazzi' Hospital, 73100, Lecce, Italy.<br /><searchLink fieldCode="AU" term="%22Bruzzese+A%22">Bruzzese A</searchLink>; Department of Onco-Hematology, Hematology Unit, Cosenza, Italy.<br /><searchLink fieldCode="AU" term="%22Di+Renzo+N%22">Di Renzo N</searchLink>; Hematology and Stem Cell Transplant Unit, 'Vito Fazzi' Hospital, 73100, Lecce, Italy.<br /><searchLink fieldCode="AU" term="%22Gentile+M%22">Gentile M</searchLink>; Department of Onco-Hematology, Hematology Unit, Cosenza, Italy.<br /><searchLink fieldCode="AU" term="%22Tarantini+G%22">Tarantini G</searchLink>; Hematology and Transplant Unit, Dimiccoli Hospital, 76121, Barletta, BT, Italy.<br /><searchLink fieldCode="AU" term="%22Mele+A%22">Mele A</searchLink>; Hematology and Transplant Unit, Cardinal Panico Hospital, 73039, Tricase, Italy.<br /><searchLink fieldCode="AU" term="%22Guarini+A%22">Guarini A</searchLink>; U.O. Di Ematologia, IRCCS Istituto Tumori Giovanni Paolo II, Bari, Italy.<br /><searchLink fieldCode="AU" term="%22Melillo+LMA%22">Melillo LMA</searchLink>; Hematology and Transplant Unit, Policlinico Foggia Ospedaliero-Universitario, Foggia, Italy.<br /><searchLink fieldCode="AU" term="%22Carella+AM%22">Carella AM</searchLink>; Hematology, Ospedale Casa Sollievo Della Sofferenza, San Giovanni Rotondo, Foggia, Italy.<br /><searchLink fieldCode="AU" term="%22Pastore+D%22">Pastore D</searchLink>; Hematology Unit, A. Perrino Hospital, 72100, Brindisi, Italy.<br /><searchLink fieldCode="AU" term="%22Frigeri+F%22">Frigeri F</searchLink>; AORN S. Anna E S. Sebastiano, Caserta, Italy.<br /><searchLink fieldCode="AU" term="%22Maggi+A%22">Maggi A</searchLink>; Hematology Unit, Department of Hematology-Oncology, Moscati Hospital, 74010, Taranto, Italy.<br /><searchLink fieldCode="AU" term="%22Cumbo+C%22">Cumbo C</searchLink>; Department of Precision and Regenerative Medicine and Ionian Area - DiMePRe-J - Azienda Ospedaliero Universitaria Consorziale Policlinico - Hematology and Stem Cell Transplantation Unit, University of Bari 'Aldo Moro', P.zza G. Cesare, 11, 70124, Bari, Italy.<br /><searchLink fieldCode="AU" term="%22Specchia+G%22">Specchia G</searchLink>; School of Medicine, University of Bari 'Aldo Moro', 70124, Bari, Italy.<br /><searchLink fieldCode="AU" term="%22Musto+P%22">Musto P</searchLink>; Department of Precision and Regenerative Medicine and Ionian Area - DiMePRe-J - Azienda Ospedaliero Universitaria Consorziale Policlinico - Hematology and Stem Cell Transplantation Unit, University of Bari 'Aldo Moro', P.zza G. Cesare, 11, 70124, Bari, Italy.<br /><searchLink fieldCode="AU" term="%22Albano+F%22">Albano F</searchLink>; Department of Precision and Regenerative Medicine and Ionian Area - DiMePRe-J - Azienda Ospedaliero Universitaria Consorziale Policlinico - Hematology and Stem Cell Transplantation Unit, University of Bari 'Aldo Moro', P.zza G. Cesare, 11, 70124, Bari, Italy. francesco.albano@uniba.it.
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