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Disrupted astrocyte-neuron glutamine-glutamate cycling in the medial prefrontal cortex contributes to depression-like behaviors.

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Title: Disrupted astrocyte-neuron glutamine-glutamate cycling in the medial prefrontal cortex contributes to depression-like behaviors.
Authors: Kang JS; Department of Anatomy and Convergence Medical Sciences, College of Medicine, Institute of Medical Science, Tyrosine Peptide Multiuse Research Group, Anti-aging Bio Cell Factory Regional Leading Research Center, Gyeongsang National University, Jinju, 52727, Republic of Korea., Baek JH; Department of Anatomy and Convergence Medical Sciences, College of Medicine, Institute of Medical Science, Tyrosine Peptide Multiuse Research Group, Anti-aging Bio Cell Factory Regional Leading Research Center, Gyeongsang National University, Jinju, 52727, Republic of Korea., Park H; Department of Anatomy and Convergence Medical Sciences, College of Medicine, Institute of Medical Science, Tyrosine Peptide Multiuse Research Group, Anti-aging Bio Cell Factory Regional Leading Research Center, Gyeongsang National University, Jinju, 52727, Republic of Korea., Rehman NU; College of Pharmacy and Research Institute of Pharmaceutical Sciences, Gyeongsang National University, Jinju, 52828, Republic of Korea., Chung HJ; College of Pharmacy and Research Institute of Pharmaceutical Sciences, Gyeongsang National University, Jinju, 52828, Republic of Korea., Lee DK; Department of Physiology and Convergence Medical Sciences, College of Medicine, Institute of Medical Science, Tyrosine Peptide Multiuse Research Group, Gyeongsang National University, Jinju, 52727, Republic of Korea., Oh S; Department of Medical Science, College of Medicine, Catholic Kwandong University, Incheon 22711, Republic of Korea., Kim HJ; Department of Anatomy and Convergence Medical Sciences, College of Medicine, Institute of Medical Science, Tyrosine Peptide Multiuse Research Group, Anti-aging Bio Cell Factory Regional Leading Research Center, Gyeongsang National University, Jinju, 52727, Republic of Korea.
Source: International journal of biological sciences [Int J Biol Sci] 2026 Jan 01; Vol. 22 (2), pp. 553-565. Date of Electronic Publication: 2026 Jan 01 (Print Publication: 2026).
Publication Type: Journal Article
Journal Info: Publisher: Ivyspring International Country of Publication: Australia NLM ID: 101235568 Publication Model: eCollection Cited Medium: Internet ISSN: 1449-2288 (Electronic) Linking ISSN: 14492288 NLM ISO Abbreviation: Int J Biol Sci Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Disrupted astrocyte-neuron glutamine-glutamate cycling in the medial prefrontal cortex contributes to depression-like behaviors.
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  Data: <searchLink fieldCode="AU" term="%22Kang+JS%22">Kang JS</searchLink>; Department of Anatomy and Convergence Medical Sciences, College of Medicine, Institute of Medical Science, Tyrosine Peptide Multiuse Research Group, Anti-aging Bio Cell Factory Regional Leading Research Center, Gyeongsang National University, Jinju, 52727, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Baek+JH%22">Baek JH</searchLink>; Department of Anatomy and Convergence Medical Sciences, College of Medicine, Institute of Medical Science, Tyrosine Peptide Multiuse Research Group, Anti-aging Bio Cell Factory Regional Leading Research Center, Gyeongsang National University, Jinju, 52727, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Park+H%22">Park H</searchLink>; Department of Anatomy and Convergence Medical Sciences, College of Medicine, Institute of Medical Science, Tyrosine Peptide Multiuse Research Group, Anti-aging Bio Cell Factory Regional Leading Research Center, Gyeongsang National University, Jinju, 52727, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Rehman+NU%22">Rehman NU</searchLink>; College of Pharmacy and Research Institute of Pharmaceutical Sciences, Gyeongsang National University, Jinju, 52828, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Chung+HJ%22">Chung HJ</searchLink>; College of Pharmacy and Research Institute of Pharmaceutical Sciences, Gyeongsang National University, Jinju, 52828, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Lee+DK%22">Lee DK</searchLink>; Department of Physiology and Convergence Medical Sciences, College of Medicine, Institute of Medical Science, Tyrosine Peptide Multiuse Research Group, Gyeongsang National University, Jinju, 52727, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Oh+S%22">Oh S</searchLink>; Department of Medical Science, College of Medicine, Catholic Kwandong University, Incheon 22711, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Kim+HJ%22">Kim HJ</searchLink>; Department of Anatomy and Convergence Medical Sciences, College of Medicine, Institute of Medical Science, Tyrosine Peptide Multiuse Research Group, Anti-aging Bio Cell Factory Regional Leading Research Center, Gyeongsang National University, Jinju, 52727, Republic of Korea.
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  Data: <searchLink fieldCode="JN" term="%22101235568%22">International journal of biological sciences</searchLink> [Int J Biol Sci] 2026 Jan 01; Vol. 22 (2), pp. 553-565. <i>Date of Electronic Publication: </i>2026 Jan 01 (<i>Print Publication: </i>2026).
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        Value: 10.7150/ijbs.123740
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        Text: English
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              Text: 2026 Jan 01
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