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Model-Based Alternative Dosing Strategies for Subcutaneous Nivolumab to Improve Cost Effectiveness.

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Title: Model-Based Alternative Dosing Strategies for Subcutaneous Nivolumab to Improve Cost Effectiveness.
Authors: Wang Y; Department of Clinical Pharmacy and Toxicology, Leiden University Medical Center, Albinusdreef 2, 2333 ZA, Leiden, The Netherlands., Bukkems LH; Department of Clinical Pharmacy and Toxicology, Leiden University Medical Center, Albinusdreef 2, 2333 ZA, Leiden, The Netherlands., Ter Heine R; Department of Pharmacy, Pharmacology and Toxicology, Radboudumc, Nijmegen, The Netherlands., van Hasselt JGC; Leiden Academic of Drug Research, Leiden, The Netherlands., Koolen SLW; Department of Medical Oncology, Erasmus MC Cancer Institute, Rotterdam, The Netherlands.; Department of Hospital Pharmacy, Erasmus University Medical Center, Rotterdam, The Netherlands., Hendrikx JJMA; Department of Pharmacy and Pharmacology, Netherlands Cancer Institute, Amsterdam, The Netherlands.; Department of Nuclear Medicine, Netherlands Cancer Institute, Amsterdam, The Netherlands., Van der Hulle T; Department of Medical Oncology, Leiden University Medical Center, Leiden, The Netherlands., Kapiteijn E; Department of Medical Oncology, Leiden University Medical Center, Leiden, The Netherlands., Zwaveling J; Department of Clinical Pharmacy and Toxicology, Leiden University Medical Center, Albinusdreef 2, 2333 ZA, Leiden, The Netherlands., Becker A; Department of Pulmonology, Amsterdam University Medical Center, Amsterdam, The Netherlands., van den Heuvel MM; Department of Pulmonology, University Medical Center Utrecht, Utrecht, The Netherlands., Theelen WSME; Department of Thoracic Oncology, Netherlands Cancer Institute, Amsterdam, The Netherlands., Oude Munnink TH; Department of Clinical Pharmacy and Pharmacology, University Medical Center Groningen, Groningen, The Netherlands., Smit EF; Department of Pulmonology, Leiden University Medical Center, Leiden, The Netherlands., Guchelaar HJ; Department of Clinical Pharmacy and Toxicology, Leiden University Medical Center, Albinusdreef 2, 2333 ZA, Leiden, The Netherlands., Moes DJAR; Department of Clinical Pharmacy and Toxicology, Leiden University Medical Center, Albinusdreef 2, 2333 ZA, Leiden, The Netherlands. d.j.a.r.moes@lumc.nl.
Source: Clinical pharmacokinetics [Clin Pharmacokinet] 2026 Apr; Vol. 65 (4), pp. 621-632. Date of Electronic Publication: 2026 Jan 12.
Publication Type: Journal Article
Journal Info: Publisher: Country of Publication: Switzerland NLM ID: 7606849 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1179-1926 (Electronic) Linking ISSN: 03125963 NLM ISO Abbreviation: Clin Pharmacokinet Subsets: MEDLINE
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  Data: Model-Based Alternative Dosing Strategies for Subcutaneous Nivolumab to Improve Cost Effectiveness.
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  Data: <searchLink fieldCode="AU" term="%22Wang+Y%22">Wang Y</searchLink>; Department of Clinical Pharmacy and Toxicology, Leiden University Medical Center, Albinusdreef 2, 2333 ZA, Leiden, The Netherlands.<br /><searchLink fieldCode="AU" term="%22Bukkems+LH%22">Bukkems LH</searchLink>; Department of Clinical Pharmacy and Toxicology, Leiden University Medical Center, Albinusdreef 2, 2333 ZA, Leiden, The Netherlands.<br /><searchLink fieldCode="AU" term="%22Ter+Heine+R%22">Ter Heine R</searchLink>; Department of Pharmacy, Pharmacology and Toxicology, Radboudumc, Nijmegen, The Netherlands.<br /><searchLink fieldCode="AU" term="%22van+Hasselt+JGC%22">van Hasselt JGC</searchLink>; Leiden Academic of Drug Research, Leiden, The Netherlands.<br /><searchLink fieldCode="AU" term="%22Koolen+SLW%22">Koolen SLW</searchLink>; Department of Medical Oncology, Erasmus MC Cancer Institute, Rotterdam, The Netherlands.; Department of Hospital Pharmacy, Erasmus University Medical Center, Rotterdam, The Netherlands.<br /><searchLink fieldCode="AU" term="%22Hendrikx+JJMA%22">Hendrikx JJMA</searchLink>; Department of Pharmacy and Pharmacology, Netherlands Cancer Institute, Amsterdam, The Netherlands.; Department of Nuclear Medicine, Netherlands Cancer Institute, Amsterdam, The Netherlands.<br /><searchLink fieldCode="AU" term="%22Van+der+Hulle+T%22">Van der Hulle T</searchLink>; Department of Medical Oncology, Leiden University Medical Center, Leiden, The Netherlands.<br /><searchLink fieldCode="AU" term="%22Kapiteijn+E%22">Kapiteijn E</searchLink>; Department of Medical Oncology, Leiden University Medical Center, Leiden, The Netherlands.<br /><searchLink fieldCode="AU" term="%22Zwaveling+J%22">Zwaveling J</searchLink>; Department of Clinical Pharmacy and Toxicology, Leiden University Medical Center, Albinusdreef 2, 2333 ZA, Leiden, The Netherlands.<br /><searchLink fieldCode="AU" term="%22Becker+A%22">Becker A</searchLink>; Department of Pulmonology, Amsterdam University Medical Center, Amsterdam, The Netherlands.<br /><searchLink fieldCode="AU" term="%22van+den+Heuvel+MM%22">van den Heuvel MM</searchLink>; Department of Pulmonology, University Medical Center Utrecht, Utrecht, The Netherlands.<br /><searchLink fieldCode="AU" term="%22Theelen+WSME%22">Theelen WSME</searchLink>; Department of Thoracic Oncology, Netherlands Cancer Institute, Amsterdam, The Netherlands.<br /><searchLink fieldCode="AU" term="%22Oude+Munnink+TH%22">Oude Munnink TH</searchLink>; Department of Clinical Pharmacy and Pharmacology, University Medical Center Groningen, Groningen, The Netherlands.<br /><searchLink fieldCode="AU" term="%22Smit+EF%22">Smit EF</searchLink>; Department of Pulmonology, Leiden University Medical Center, Leiden, The Netherlands.<br /><searchLink fieldCode="AU" term="%22Guchelaar+HJ%22">Guchelaar HJ</searchLink>; Department of Clinical Pharmacy and Toxicology, Leiden University Medical Center, Albinusdreef 2, 2333 ZA, Leiden, The Netherlands.<br /><searchLink fieldCode="AU" term="%22Moes+DJAR%22">Moes DJAR</searchLink>; Department of Clinical Pharmacy and Toxicology, Leiden University Medical Center, Albinusdreef 2, 2333 ZA, Leiden, The Netherlands. d.j.a.r.moes@lumc.nl.
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  Data: <searchLink fieldCode="JN" term="%227606849%22">Clinical pharmacokinetics</searchLink> [Clin Pharmacokinet] 2026 Apr; Vol. 65 (4), pp. 621-632. <i>Date of Electronic Publication: </i>2026 Jan 12.
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