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HSP60 Mediates NLRP3 Inflammasome-Dependent Microglial Pyroptosis Via the TLR4/MyD88/NF-κB Signaling Axis After Subarachnoid Hemorrhage.

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Title: HSP60 Mediates NLRP3 Inflammasome-Dependent Microglial Pyroptosis Via the TLR4/MyD88/NF-κB Signaling Axis After Subarachnoid Hemorrhage.
Authors: Hu ZQ; Department of Neurosurgery, The Translational Research Institute for Neurological Disorders of Wannan Medical College, the First Affiliated Hospital of Wannan Medical College (Yijishan Hospital of Wannan Medical College), No.2 West Zheshan Road, Wuhu, Anhui, 241001, China., Ma R; Department of Neurosurgery, The Translational Research Institute for Neurological Disorders of Wannan Medical College, the First Affiliated Hospital of Wannan Medical College (Yijishan Hospital of Wannan Medical College), No.2 West Zheshan Road, Wuhu, Anhui, 241001, China., Zhang H; Department of Neurosurgery, The Translational Research Institute for Neurological Disorders of Wannan Medical College, the First Affiliated Hospital of Wannan Medical College (Yijishan Hospital of Wannan Medical College), No.2 West Zheshan Road, Wuhu, Anhui, 241001, China., Miao J; Department of Neurosurgery, The Translational Research Institute for Neurological Disorders of Wannan Medical College, the First Affiliated Hospital of Wannan Medical College (Yijishan Hospital of Wannan Medical College), No.2 West Zheshan Road, Wuhu, Anhui, 241001, China., Sun JQ; Department of Neurosurgery, Affiliated Hospital of Medical School, Nanjing Drum Tower Hospital, Nanjing University, Nanjing, 210002, China., Yuan J; Department of Neurosurgery, The Translational Research Institute for Neurological Disorders of Wannan Medical College, the First Affiliated Hospital of Wannan Medical College (Yijishan Hospital of Wannan Medical College), No.2 West Zheshan Road, Wuhu, Anhui, 241001, China., Liu J; Department of Neurosurgery, The Translational Research Institute for Neurological Disorders of Wannan Medical College, the First Affiliated Hospital of Wannan Medical College (Yijishan Hospital of Wannan Medical College), No.2 West Zheshan Road, Wuhu, Anhui, 241001, China., Zhang Z; Department of Neurosurgery, The Translational Research Institute for Neurological Disorders of Wannan Medical College, the First Affiliated Hospital of Wannan Medical College (Yijishan Hospital of Wannan Medical College), No.2 West Zheshan Road, Wuhu, Anhui, 241001, China., Xia D; Department of Neurosurgery, The Translational Research Institute for Neurological Disorders of Wannan Medical College, the First Affiliated Hospital of Wannan Medical College (Yijishan Hospital of Wannan Medical College), No.2 West Zheshan Road, Wuhu, Anhui, 241001, China. xiady1981@163.com.
Source: Inflammation [Inflammation] 2026 Jan 12; Vol. 49 (1), pp. 41. Date of Electronic Publication: 2026 Jan 12.
Publication Type: Journal Article
Journal Info: Publisher: Kluwer Academic/Plenum Publishers Country of Publication: United States NLM ID: 7600105 Publication Model: Electronic Cited Medium: Internet ISSN: 1573-2576 (Electronic) Linking ISSN: 03603997 NLM ISO Abbreviation: Inflammation Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: HSP60 Mediates NLRP3 Inflammasome-Dependent Microglial Pyroptosis Via the TLR4/MyD88/NF-κB Signaling Axis After Subarachnoid Hemorrhage.
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  Data: <searchLink fieldCode="AU" term="%22Hu+ZQ%22">Hu ZQ</searchLink>; Department of Neurosurgery, The Translational Research Institute for Neurological Disorders of Wannan Medical College, the First Affiliated Hospital of Wannan Medical College (Yijishan Hospital of Wannan Medical College), No.2 West Zheshan Road, Wuhu, Anhui, 241001, China.<br /><searchLink fieldCode="AU" term="%22Ma+R%22">Ma R</searchLink>; Department of Neurosurgery, The Translational Research Institute for Neurological Disorders of Wannan Medical College, the First Affiliated Hospital of Wannan Medical College (Yijishan Hospital of Wannan Medical College), No.2 West Zheshan Road, Wuhu, Anhui, 241001, China.<br /><searchLink fieldCode="AU" term="%22Zhang+H%22">Zhang H</searchLink>; Department of Neurosurgery, The Translational Research Institute for Neurological Disorders of Wannan Medical College, the First Affiliated Hospital of Wannan Medical College (Yijishan Hospital of Wannan Medical College), No.2 West Zheshan Road, Wuhu, Anhui, 241001, China.<br /><searchLink fieldCode="AU" term="%22Miao+J%22">Miao J</searchLink>; Department of Neurosurgery, The Translational Research Institute for Neurological Disorders of Wannan Medical College, the First Affiliated Hospital of Wannan Medical College (Yijishan Hospital of Wannan Medical College), No.2 West Zheshan Road, Wuhu, Anhui, 241001, China.<br /><searchLink fieldCode="AU" term="%22Sun+JQ%22">Sun JQ</searchLink>; Department of Neurosurgery, Affiliated Hospital of Medical School, Nanjing Drum Tower Hospital, Nanjing University, Nanjing, 210002, China.<br /><searchLink fieldCode="AU" term="%22Yuan+J%22">Yuan J</searchLink>; Department of Neurosurgery, The Translational Research Institute for Neurological Disorders of Wannan Medical College, the First Affiliated Hospital of Wannan Medical College (Yijishan Hospital of Wannan Medical College), No.2 West Zheshan Road, Wuhu, Anhui, 241001, China.<br /><searchLink fieldCode="AU" term="%22Liu+J%22">Liu J</searchLink>; Department of Neurosurgery, The Translational Research Institute for Neurological Disorders of Wannan Medical College, the First Affiliated Hospital of Wannan Medical College (Yijishan Hospital of Wannan Medical College), No.2 West Zheshan Road, Wuhu, Anhui, 241001, China.<br /><searchLink fieldCode="AU" term="%22Zhang+Z%22">Zhang Z</searchLink>; Department of Neurosurgery, The Translational Research Institute for Neurological Disorders of Wannan Medical College, the First Affiliated Hospital of Wannan Medical College (Yijishan Hospital of Wannan Medical College), No.2 West Zheshan Road, Wuhu, Anhui, 241001, China.<br /><searchLink fieldCode="AU" term="%22Xia+D%22">Xia D</searchLink>; Department of Neurosurgery, The Translational Research Institute for Neurological Disorders of Wannan Medical College, the First Affiliated Hospital of Wannan Medical College (Yijishan Hospital of Wannan Medical College), No.2 West Zheshan Road, Wuhu, Anhui, 241001, China. xiady1981@163.com.
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  Data: <searchLink fieldCode="JN" term="%227600105%22">Inflammation</searchLink> [Inflammation] 2026 Jan 12; Vol. 49 (1), pp. 41. <i>Date of Electronic Publication: </i>2026 Jan 12.
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        Value: 10.1007/s10753-025-02442-x
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        Text: English
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      – TitleFull: HSP60 Mediates NLRP3 Inflammasome-Dependent Microglial Pyroptosis Via the TLR4/MyD88/NF-κB Signaling Axis After Subarachnoid Hemorrhage.
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              Text: 2026 Jan 12
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