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A label-free multi-parameter screening method for predicting the stability of mRNA-LNP formulations.

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Title: A label-free multi-parameter screening method for predicting the stability of mRNA-LNP formulations.
Authors: Sun Y; Institute of Drug Metabolism and Pharmaceutical Analysis, College of Pharmaceutical Sciences, Zhejiang University, Hangzhou 310058, China., Ye CH; Institute of Drug Metabolism and Pharmaceutical Analysis, College of Pharmaceutical Sciences, Zhejiang University, Hangzhou 310058, China; Taizhou Institute of Zhejiang University, Taizhou 317000, China; College of Bioengineering, Zhejiang University of Technology, Hangzhou 310014, China., Gao H; Institute of Drug Metabolism and Pharmaceutical Analysis, College of Pharmaceutical Sciences, Zhejiang University, Hangzhou 310058, China; Taizhou Institute of Zhejiang University, Taizhou 317000, China., Wu SY; Institute of Drug Metabolism and Pharmaceutical Analysis, College of Pharmaceutical Sciences, Zhejiang University, Hangzhou 310058, China., Fang WJ; Institute of Drug Metabolism and Pharmaceutical Analysis, College of Pharmaceutical Sciences, Zhejiang University, Hangzhou 310058, China; Taizhou Institute of Zhejiang University, Taizhou 317000, China; Innovation Center of Translational Pharmacy, Jinhua Institute of Zhejiang University, Jinhua 321000, China. Electronic address: wjfang@zju.edu.cn.
Source: International journal of pharmaceutics [Int J Pharm] 2026 Feb 20; Vol. 691, pp. 126576. Date of Electronic Publication: 2026 Jan 10.
Publication Type: Journal Article
Journal Info: Publisher: Elsevier/North-Holland Biomedical Press Country of Publication: Netherlands NLM ID: 7804127 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1873-3476 (Electronic) Linking ISSN: 03785173 NLM ISO Abbreviation: Int J Pharm Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: A label-free multi-parameter screening method for predicting the stability of mRNA-LNP formulations.
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  Data: <searchLink fieldCode="AU" term="%22Sun+Y%22">Sun Y</searchLink>; Institute of Drug Metabolism and Pharmaceutical Analysis, College of Pharmaceutical Sciences, Zhejiang University, Hangzhou 310058, China.<br /><searchLink fieldCode="AU" term="%22Ye+CH%22">Ye CH</searchLink>; Institute of Drug Metabolism and Pharmaceutical Analysis, College of Pharmaceutical Sciences, Zhejiang University, Hangzhou 310058, China; Taizhou Institute of Zhejiang University, Taizhou 317000, China; College of Bioengineering, Zhejiang University of Technology, Hangzhou 310014, China.<br /><searchLink fieldCode="AU" term="%22Gao+H%22">Gao H</searchLink>; Institute of Drug Metabolism and Pharmaceutical Analysis, College of Pharmaceutical Sciences, Zhejiang University, Hangzhou 310058, China; Taizhou Institute of Zhejiang University, Taizhou 317000, China.<br /><searchLink fieldCode="AU" term="%22Wu+SY%22">Wu SY</searchLink>; Institute of Drug Metabolism and Pharmaceutical Analysis, College of Pharmaceutical Sciences, Zhejiang University, Hangzhou 310058, China.<br /><searchLink fieldCode="AU" term="%22Fang+WJ%22">Fang WJ</searchLink>; Institute of Drug Metabolism and Pharmaceutical Analysis, College of Pharmaceutical Sciences, Zhejiang University, Hangzhou 310058, China; Taizhou Institute of Zhejiang University, Taizhou 317000, China; Innovation Center of Translational Pharmacy, Jinhua Institute of Zhejiang University, Jinhua 321000, China. Electronic address: wjfang@zju.edu.cn.
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  Data: <searchLink fieldCode="JN" term="%227804127%22">International journal of pharmaceutics</searchLink> [Int J Pharm] 2026 Feb 20; Vol. 691, pp. 126576. <i>Date of Electronic Publication: </i>2026 Jan 10.
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        Value: 10.1016/j.ijpharm.2026.126576
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              Text: 2026 Feb 20
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