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Comparative efficacy of immune checkpoint inhibitor combination therapies by metastatic site in metastatic renal cell carcinoma.

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Title: Comparative efficacy of immune checkpoint inhibitor combination therapies by metastatic site in metastatic renal cell carcinoma.
Authors: Toyoda S; Department of Urology, Faculty of Medicine, Kindai University, 377-2, Ohnohigashi, Osaka-Sayama, Osaka, Japan., Inoki L; Department of Urology, Faculty of Medicine, Kindai University, 377-2, Ohnohigashi, Osaka-Sayama, Osaka, Japan., Hashimoto M; Department of Urology, Faculty of Medicine, Kindai University, 377-2, Ohnohigashi, Osaka-Sayama, Osaka, Japan., Fukuokaya W; Department of Urology, The Jikei University School of Medicine, Minato-ku, Tokyo, Japan., Mori K; Department of Urology, The Jikei University School of Medicine, Minato-ku, Tokyo, Japan., Nishimura S; Department of Urology, Dentistry and Pharmaceutical Sciences, Okayama University Graduate School of Medicine, Okayama, Japan., Maenosono R; Department of Urology, Osaka Medical and Pharmaceutical University, Takatsuki, Osaka, Japan., Iwata T; Department of Urology, Dentistry and Pharmaceutical Sciences, Okayama University Graduate School of Medicine, Okayama, Japan., Bekku K; Department of Urology, Dentistry and Pharmaceutical Sciences, Okayama University Graduate School of Medicine, Okayama, Japan., Nukaya T; Department of Urology, Fujita-Health University School of Medicine, Toyoake, Aichi, Japan., Yanagisawa T; Department of Urology, The Jikei University School of Medicine, Minato-ku, Tokyo, Japan., Tsujino T; Department of Urology, Osaka Medical and Pharmaceutical University, Takatsuki, Osaka, Japan., Komura K; Department of Urology, Kawasaki University School of Medicine, Kurashiki, Japan., Takahara K; Department of Urology, Fujita-Health University School of Medicine, Toyoake, Aichi, Japan., Inamoto T; Department of Urology, Hamamatsu University School of Medicine, Hamamatsu, Japan., Azuma H; Department of Urology, Osaka Medical and Pharmaceutical University, Takatsuki, Osaka, Japan., Fujita K; Department of Urology, Faculty of Medicine, Kindai University, 377-2, Ohnohigashi, Osaka-Sayama, Osaka, Japan. kfujita@med.kindai.ac.jp.
Corporate Authors: JK-FOOT study group
Source: Scientific reports [Sci Rep] 2026 Jan 13; Vol. 16 (1), pp. 3303. Date of Electronic Publication: 2026 Jan 13.
Publication Type: Clinical Study; Comparative Study; Journal Article; Multicenter Study
Journal Info: Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101563288 Publication Model: Electronic Cited Medium: Internet ISSN: 2045-2322 (Electronic) Linking ISSN: 20452322 NLM ISO Abbreviation: Sci Rep Subsets: MEDLINE
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  Data: <searchLink fieldCode="AU" term="%22Toyoda+S%22">Toyoda S</searchLink>; Department of Urology, Faculty of Medicine, Kindai University, 377-2, Ohnohigashi, Osaka-Sayama, Osaka, Japan.<br /><searchLink fieldCode="AU" term="%22Inoki+L%22">Inoki L</searchLink>; Department of Urology, Faculty of Medicine, Kindai University, 377-2, Ohnohigashi, Osaka-Sayama, Osaka, Japan.<br /><searchLink fieldCode="AU" term="%22Hashimoto+M%22">Hashimoto M</searchLink>; Department of Urology, Faculty of Medicine, Kindai University, 377-2, Ohnohigashi, Osaka-Sayama, Osaka, Japan.<br /><searchLink fieldCode="AU" term="%22Fukuokaya+W%22">Fukuokaya W</searchLink>; Department of Urology, The Jikei University School of Medicine, Minato-ku, Tokyo, Japan.<br /><searchLink fieldCode="AU" term="%22Mori+K%22">Mori K</searchLink>; Department of Urology, The Jikei University School of Medicine, Minato-ku, Tokyo, Japan.<br /><searchLink fieldCode="AU" term="%22Nishimura+S%22">Nishimura S</searchLink>; Department of Urology, Dentistry and Pharmaceutical Sciences, Okayama University Graduate School of Medicine, Okayama, Japan.<br /><searchLink fieldCode="AU" term="%22Maenosono+R%22">Maenosono R</searchLink>; Department of Urology, Osaka Medical and Pharmaceutical University, Takatsuki, Osaka, Japan.<br /><searchLink fieldCode="AU" term="%22Iwata+T%22">Iwata T</searchLink>; Department of Urology, Dentistry and Pharmaceutical Sciences, Okayama University Graduate School of Medicine, Okayama, Japan.<br /><searchLink fieldCode="AU" term="%22Bekku+K%22">Bekku K</searchLink>; Department of Urology, Dentistry and Pharmaceutical Sciences, Okayama University Graduate School of Medicine, Okayama, Japan.<br /><searchLink fieldCode="AU" term="%22Nukaya+T%22">Nukaya T</searchLink>; Department of Urology, Fujita-Health University School of Medicine, Toyoake, Aichi, Japan.<br /><searchLink fieldCode="AU" term="%22Yanagisawa+T%22">Yanagisawa T</searchLink>; Department of Urology, The Jikei University School of Medicine, Minato-ku, Tokyo, Japan.<br /><searchLink fieldCode="AU" term="%22Tsujino+T%22">Tsujino T</searchLink>; Department of Urology, Osaka Medical and Pharmaceutical University, Takatsuki, Osaka, Japan.<br /><searchLink fieldCode="AU" term="%22Komura+K%22">Komura K</searchLink>; Department of Urology, Kawasaki University School of Medicine, Kurashiki, Japan.<br /><searchLink fieldCode="AU" term="%22Takahara+K%22">Takahara K</searchLink>; Department of Urology, Fujita-Health University School of Medicine, Toyoake, Aichi, Japan.<br /><searchLink fieldCode="AU" term="%22Inamoto+T%22">Inamoto T</searchLink>; Department of Urology, Hamamatsu University School of Medicine, Hamamatsu, Japan.<br /><searchLink fieldCode="AU" term="%22Azuma+H%22">Azuma H</searchLink>; Department of Urology, Osaka Medical and Pharmaceutical University, Takatsuki, Osaka, Japan.<br /><searchLink fieldCode="AU" term="%22Fujita+K%22">Fujita K</searchLink>; Department of Urology, Faculty of Medicine, Kindai University, 377-2, Ohnohigashi, Osaka-Sayama, Osaka, Japan. kfujita@med.kindai.ac.jp.
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