View in EDS

Switching from Dupilumab to Upadacitinib in Adults and Adolescents with Moderate-to-Severe Atopic Dermatitis After Inadequate Response to Dupilumab: Efficacy and Safety Results from Period 2 of Phase 3b/4 Study (LEVEL UP).

Saved in:
Bibliographic Details
Title: Switching from Dupilumab to Upadacitinib in Adults and Adolescents with Moderate-to-Severe Atopic Dermatitis After Inadequate Response to Dupilumab: Efficacy and Safety Results from Period 2 of Phase 3b/4 Study (LEVEL UP).
Authors: Bunick CG; Department of Dermatology and Program in Translational Biomedicine, Yale School of Medicine, New Haven, CT, USA. christopher.bunick@yale.edu., Magnolo N; Department of Dermatology, University Hospital Münster, Münster, Germany., Moore A; Baylor University Medical Center, Dallas, TX, USA.; Arlington Research Center, Arlington, TX, USA.; Arlington Center for Dermatology, Arlington, TX, USA., Abe M; Sapporo Skin Clinic, Sapporo, Hokkaido, Japan., Gao X; Department of Dermatology, The 1st Hospital of China Medical University, Shenyang, People's Republic of China., Lynde C; Lynde Institute for Dermatology and Lynderm Research Inc, Markham, ON, Canada., Ibrahim N; AbbVie, Inc, North Chicago, IL, USA., Levy G; AbbVie, Inc, North Chicago, IL, USA., Calimlim BM; AbbVie, Inc, North Chicago, IL, USA., Wu X; AbbVie, Inc, North Chicago, IL, USA., Armendariz Y; AbbVie, Inc, North Chicago, IL, USA., Grada A; AbbVie, Inc, North Chicago, IL, USA., Eyerich K; Department of Dermatology and Venerology, Medical Center, University of Freiburg, Freiburg, Germany.
Source: American journal of clinical dermatology [Am J Clin Dermatol] 2026 Mar; Vol. 27 (2), pp. 391-399. Date of Electronic Publication: 2026 Jan 14.
Publication Type: Journal Article; Clinical Trial, Phase III; Multicenter Study; Randomized Controlled Trial
Journal Info: Publisher: Adis, Springer International Country of Publication: New Zealand NLM ID: 100895290 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1179-1888 (Electronic) Linking ISSN: 11750561 NLM ISO Abbreviation: Am J Clin Dermatol Subsets: MEDLINE
Database: MEDLINE Ultimate
FullText Text:
  Availability: 0
Header DbId: mdl
DbLabel: MEDLINE Ultimate
An: 41533220
AccessLevel: 2
PubType: Academic Journal
PubTypeId: academicJournal
PreciseRelevancyScore: 0
IllustrationInfo
Items – Name: Title
  Label: Title
  Group: Ti
  Data: Switching from Dupilumab to Upadacitinib in Adults and Adolescents with Moderate-to-Severe Atopic Dermatitis After Inadequate Response to Dupilumab: Efficacy and Safety Results from Period 2 of Phase 3b/4 Study (LEVEL UP).
– Name: Author
  Label: Authors
  Group: Au
  Data: <searchLink fieldCode="AU" term="%22Bunick+CG%22">Bunick CG</searchLink>; Department of Dermatology and Program in Translational Biomedicine, Yale School of Medicine, New Haven, CT, USA. christopher.bunick@yale.edu.<br /><searchLink fieldCode="AU" term="%22Magnolo+N%22">Magnolo N</searchLink>; Department of Dermatology, University Hospital Münster, Münster, Germany.<br /><searchLink fieldCode="AU" term="%22Moore+A%22">Moore A</searchLink>; Baylor University Medical Center, Dallas, TX, USA.; Arlington Research Center, Arlington, TX, USA.; Arlington Center for Dermatology, Arlington, TX, USA.<br /><searchLink fieldCode="AU" term="%22Abe+M%22">Abe M</searchLink>; Sapporo Skin Clinic, Sapporo, Hokkaido, Japan.<br /><searchLink fieldCode="AU" term="%22Gao+X%22">Gao X</searchLink>; Department of Dermatology, The 1st Hospital of China Medical University, Shenyang, People's Republic of China.<br /><searchLink fieldCode="AU" term="%22Lynde+C%22">Lynde C</searchLink>; Lynde Institute for Dermatology and Lynderm Research Inc, Markham, ON, Canada.<br /><searchLink fieldCode="AU" term="%22Ibrahim+N%22">Ibrahim N</searchLink>; AbbVie, Inc, North Chicago, IL, USA.<br /><searchLink fieldCode="AU" term="%22Levy+G%22">Levy G</searchLink>; AbbVie, Inc, North Chicago, IL, USA.<br /><searchLink fieldCode="AU" term="%22Calimlim+BM%22">Calimlim BM</searchLink>; AbbVie, Inc, North Chicago, IL, USA.<br /><searchLink fieldCode="AU" term="%22Wu+X%22">Wu X</searchLink>; AbbVie, Inc, North Chicago, IL, USA.<br /><searchLink fieldCode="AU" term="%22Armendariz+Y%22">Armendariz Y</searchLink>; AbbVie, Inc, North Chicago, IL, USA.<br /><searchLink fieldCode="AU" term="%22Grada+A%22">Grada A</searchLink>; AbbVie, Inc, North Chicago, IL, USA.<br /><searchLink fieldCode="AU" term="%22Eyerich+K%22">Eyerich K</searchLink>; Department of Dermatology and Venerology, Medical Center, University of Freiburg, Freiburg, Germany.
– Name: TitleSource
  Label: Source
  Group: Src
  Data: <searchLink fieldCode="JN" term="%22100895290%22">American journal of clinical dermatology</searchLink> [Am J Clin Dermatol] 2026 Mar; Vol. 27 (2), pp. 391-399. <i>Date of Electronic Publication: </i>2026 Jan 14.
– Name: TypePub
  Label: Publication Type
  Group: TypPub
  Data: Journal Article; Clinical Trial, Phase III; Multicenter Study; Randomized Controlled Trial
– Name: TitleSource
  Label: Journal Info
  Group: Src
  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Adis%2C+Springer+International%22">Adis, Springer International </searchLink><i>Country of Publication: </i>New Zealand <i>NLM ID: </i>100895290 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1179-1888 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2211750561%22">11750561 </searchLink><i>NLM ISO Abbreviation: </i>Am J Clin Dermatol <i>Subsets: </i>MEDLINE
PLink https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=mdl&AN=41533220
RecordInfo BibRecord:
  BibEntity:
    Identifiers:
      – Type: doi
        Value: 10.1007/s40257-025-01003-0
    Languages:
      – Code: eng
        Text: English
    PhysicalDescription:
      Pagination:
        StartPage: 391
    Titles:
      – TitleFull: Switching from Dupilumab to Upadacitinib in Adults and Adolescents with Moderate-to-Severe Atopic Dermatitis After Inadequate Response to Dupilumab: Efficacy and Safety Results from Period 2 of Phase 3b/4 Study (LEVEL UP).
        Type: main
  BibRelationships:
    HasContributorRelationships:
      – PersonEntity:
          Name:
            NameFull: Bunick CG
      – PersonEntity:
          Name:
            NameFull: Magnolo N
      – PersonEntity:
          Name:
            NameFull: Moore A
      – PersonEntity:
          Name:
            NameFull: Abe M
      – PersonEntity:
          Name:
            NameFull: Gao X
      – PersonEntity:
          Name:
            NameFull: Lynde C
      – PersonEntity:
          Name:
            NameFull: Ibrahim N
      – PersonEntity:
          Name:
            NameFull: Levy G
      – PersonEntity:
          Name:
            NameFull: Calimlim BM
      – PersonEntity:
          Name:
            NameFull: Wu X
      – PersonEntity:
          Name:
            NameFull: Armendariz Y
      – PersonEntity:
          Name:
            NameFull: Grada A
      – PersonEntity:
          Name:
            NameFull: Eyerich K
    IsPartOfRelationships:
      – BibEntity:
          Dates:
            – D: 01
              M: 03
              Text: 2026 Mar
              Type: published
              Y: 2026
          Identifiers:
            – Type: issn-electronic
              Value: 1179-1888
          Numbering:
            – Type: volume
              Value: 27
            – Type: issue
              Value: 2
          Titles:
            – TitleFull: American journal of clinical dermatology
              Type: main
ResultId 1